Prevention is the key to reduce the incidence of Contrast-induced nephropathy (CIN) and it
begins with identification of the high risk patients.
Aim: Identifying the different risk factors for CIN .
Methods: This is a prospective analytical study
that has included 156 patients, all
underwent an objective exam, hematochemical measurements. The patiemts were divided
into two groups depending on the incidence of CIN defined as an increase in creatinine
level equal or more than 25% from baseline values within 48-72 hours after the coronary
procedure.
Results: Several independent risk factors for CIN were identified: age equal or more 70
year (OR:4.11, P:0.004( , contrast volume more than 200 ml )OR:3.2,P:0.01(, anemia
(OR:2.7,P:0.01), urgent cardiac catheterization) OR:3.3,P:0.02(,diabetic nephropathy
(OR:4.9,P:0.04).
Conclusion: . Increased contrast volume ,urgent cardiac catheterization elderly patients ,
anemia and diabetic nephropathy are associated with increased risk for CIN.
Purpose: Lacunar infarcts is an important stroke subgroup with unique clinical and
pathologic features, but risk factors for lacunar infarcts have been rarely documented. To
address this matter, we studied 65 patients had lacunar infarction at Depa
rtment of
Neurology , Tishreen University Hospital , Lattakia , Syria , and 65 controls during the
period between May 2017 – May 2018 .
Methods: We obtained information concerning risk factor exposure status among the
patients by a structured questionnaire , we recorded age , sex , blood pressure , glucose ,
heart diseases , cigarette smoking , alcohol drinking , physical exercise for patiens and
controls .We do laboratory tests and ECG and echocardiography and CT brain or MRI .
Results: Significantly increasing the risk of lacunar stroke were hypertension
(P-value=0.0001) and (OR=9.9), Current smokers (P-value=0.002) and (OR=5.2), diabetes
(P-value=0.001) and (OR=5.3) , whereas frequent physical exercise was associated with a
significantly decreased risk) P-value=00001( and (OR=2.6). There was no risk of
lacunar stroke associated with heart disease (P-value=0.6) (OR=0.8) , high cholesterol (Pvalue=
1) and (OR=1) , alcohol drinking (P-value=0.7) and (OR=0.8).
Conclusions: Patients with hypertension or diabetes, current smokers, those who
have not heart disease, are at a higher risk of lacunar stroke, whereas those who undertake
regular physical exercise may be at lower risk.
introduction: Diabetes mellitus is a global epidemic and a leading cause for
increasing mortality and morbidity. Although prevention and care policies exist, diabetes
continues to be a global public health problem with serious consequences. Aim: To
assess
the educational needs on diabetes among patients, level of knowledge and patient specific
characteristics that are associated with this knowledge. Method: A descriptive study was
conducted among 50 patients who entered Tishreen university between May 2017 and
December 2017. Questionnaire on different domains of diabetes such as general
knowledge, complications, treatment, life style, symptoms and prevention. Each statement
was given a score of one if it was answered correctly and zero for a wrong answer. Out of a
total score, a score of seventy percent and above was considered good knowledge ,
between thirty percent and seventy considered moderate, less than thirty considered poor
knowledge . Results: more than half, were > 50 years (54%), (54%) were males, 46% were
female. Most of educational needs were: regarding of insulin, its kinds, sides effects,
methods of prevention of diabetic foot and care it. The level of knowledge of diabetes was
moderate 63%.
Recommendation: Awareness regarding all the aspects of diabetes mellitus needs to
be increased for better control of the disease and its complications. Future studies about
effect of education program on improvement of knowledge and self care, especially about
the diabetic foot.
Background: Diabetes mellitus is a leading public health problem with increasing
incidence and long term complications. These complications are mainly a consequence of
macro-vascular and microvascular damages of the target organs. The incidence of
several
pulmonary abnormalities during the course of Diabetes Mellitus because the presence of
an extensive microvascular circulation and abundant connective tissue in the lungs , raises
the possibility that lung tissue may be a target organ in diabetic patients.
Objectives: This research is designed to study the impact of DM and both the
duration of the disease and the glycemic control on pulmonary function tests.
Methodology: This is a cross-sectional study carried out on 75 patients with type II
diabetes mellitus patients at Tishreen University Hospital in the period between October
2015 and October 2016 .We compared with a control group consisted of 75 non diabetic
healthy persons . Measurement of HbA1C , fasting plasma glucose
(FPG) , and spirometry were made to all subjects and the following pulmonary function
parameters were recorded: Forced Expiratory Volume in the first second (FEV1), Forced
Vital Capacity (FVC), and Forced Expiratory Volume percent (FEV1/ FVC%) . Results
were analyzed by calculating Mean ± SD, using X2 test , Karl Pearson correlation and
ANOVA test.
Results: The mean FEV1, FVC, FEV1/FVC% values were low in diabetics (p value
<0.05) compared to healthy non-diabetics (control group). Also, uncontrolled diabetics
show a greater decrease in these values than controlled diabetics. There was a greater
decrease in these values in patients with long period of disease .
Conclusion: The findings of the present study suggest that, the lung is a target organ
for damage in DM and diabetics show a decrease in PFTs with a restrictive pattern lesion
compared with non-diabetics . And this deterioration is exaggerated in uncontrolled
diabetics and with the long duration of DM .
Type 2 Diabetes mellitus T2DM has been suggested to be the most common
metabolic disorder associated with magnesium deficiency which has many adverse
outcomes. The aim of this study was to evaluate plasma Mg in 126 T2DM patients
recruited from Dia
betes Centre in Lattakia, compare them to 70 healthy individuals, and
assess the correlation between plasma Mg and HbA1c as a glycemic control biomarker.
Magnesium was measured using xylidyl blue colorimetric method. HbA1c was measured
using ion-exchange resin separation. The SPSS 19.0 software was used for statistical
analysis. Mean plasma Mg concentrations of the diabetics was significantly lower than
controls (P=0.0001). Plasma magnesium was negatively correlated with HbA1c (r=-0.5,
P=0.0002). Plasma magnesium was below the normal reference range (1.9-2.5 mg/dL) in
47.6% of diabetics and 28.6% of controls. In conclusion, it is important to monitor Mg
levels in both T2DM patients and non-diabetics and take procedures to correct
hypomagnesaemia states.
Background: Diabetes mellitus type2 (T2DM) and thyroid dysfunction (TD) are the
two most common endocrine disorders in clinical practice. The unrecognized TD may
adversely affect the metabolic control and add more risk to an already predisposing
s
cenario for cardiovascular diseases. The objective of this study was to investigate the
prevalence of TD in patients with type2 diabetes mellitus.
Objective: To determine the prevalence and patterns of thyroid dysfunction in
patients with type2 diabetes mellitus.
Material and methods: Study included total 362 subjects (204 type2 diabetic patients
and 158 healthy non diabetic subjects). Agroup of type2 diabetic patients and control group
were evaluated for thyroid dysfunction by testing TSH and FT4 when TSH was abnormal.
The correlation of prevalence of thyroid disorder with gender distribution, age distribution,
duration of diabetes, BMI, treatment, fasting plasma glucose (FPG), serum triglyceride and
serum cholesterol was then done in diabetic patients. The observations and interpretations
were recorded and results obtained were statistically analyzed.
Results: The prevalence of thyroid dysfunction among type2 diabetic patients was
found to be 13,2%. In the control group, the prevalence of thyroid dysfunction was 6,3%.
There was a significant difference between diabetics and control subjects p= 0,031.The
most frequently TD in type2 diabetic patients was subclinical hypothyroidism (8,3%).
Thyroid dysfunction was significantly correlated with gender (women > man), age < 60
years, FPG > 130mg/dl, TG > 150mg/dl and insulin treatment in type2 diabetic patients.
Conclusion: Screening of thyroid dysfunction shoud be done in all Type2 diabetic
patients.
This study aimed to evaluate the clinical and microbiological effect
of fluoride in drinking water on the severity of chronic periodontitis
and its effect on the relationship between diabetes and periodontitis.
Gestational Diabetes Mellitus (GDM) is one of the most common complications
during pregnancy. The prevalence of gestational diabetes (GDM) is increasing all over the
world. Hence, the impact of GDM on maternal and infant health is an important topi
c of
research.
Objective:
The aim of the study was to determine the prevalence of GDM, and to assess the
impact of universal screening to detect Gestational diabetes mellitus.
Subjects and methods:
A representative sample of 760 pregnant women who attended the antenatal
department of Al Assad Hospital in Lattakia were surveyed during the period from June
1st, 2013 to December 1st, 2014. The questionnaire covered variables related maternal age,
gestational age, BMI, and women underwent the diagnostic tests for GDM. 73 pregnant
women had positive results.
The research try to defined the Temperament Models of sample of diabetes type II In The City Of Lattakia, as well as to identify differences in the differences between the mean responses of patients with diabetes type II on a scale of Temperament Mod
els to the variables (sex, place of residence). Use the search descriptive analytical method. Application a scale of Temperament Models on the sample included (350) male and female patients, for the year 2013/2014. Pilot sample consisted of (50) patients, Reliability was established by Cronbach – Alpha Reliability at lest (0.75), and (0.869) by Spearman-Brown. Results showed that the field of the power to cease operations was the most spreading between Diabetes patients, and came after the dynamic operations of Neurotic field, at last the force in the excitement field, there are statistically significant differences according to six in favor of female, there are no statistically significant differences according to place of residence.
Skin tags are common benign skin tumors usually occurring on the neck and major flexors of older people. Objective: To investigate and compare the prevalence of diabetes and disorders of triglycerides, cholesterol, LDL, and HDL levels in patients wit
h skin tags and a control group. A case-control study was conducted in individuals between (25-70) years old, comparing cases (n=107) and age-, sex-matched controls (n=97) without skin tag. Cases and controls were recruited from patients consecutively seen at the outpatient dermatology clinic at Al-Assad University Hospital in Lattakia. All patients underwent standard laboratory tests of fasting blood sugar , triglycerides , cholesterol , LDL , and HDL levels.
Results: Patients with skin tags had higher frequency of diabetes and higher levels of triglycerides , cholesterol , and LDL than the control group (P <=0.0001) and lower levels of HDL in patients with skin tags than the control group (P<=0.001). A positive correlation was found between the existing of skin tags and high BMI comparing with the control group (P<=0.0001).
According to our results, skin tags might be a useful clinical sign that could alert clinicians to screen patients with skin tags for abnormal lipids, type 2 diabetes mellitus, and cardiovascular disease, and guide patients with skin tags to modify their life style, avoiding risk factors and making clinical laboratory check-up periodically