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Register a new userStudy of risk factors in patients with lacunar infarcts
دراسة عوامل الخطورة عند مرضى الاحتشاءات الفجوية
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Tishreen University ورقة بحثية
Publication date
2018
fields
Medicine
and research's language is
العربية
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Shamra Editor
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الهدف : الاحتشاءات الفجوية نمط من النشبات الدماغية تمتلك مظاهر سريرية و إمراضية فريدة ، و لكن عوامل الخطورة لهذه الاحتشاءات نادراً ما تكون مدروسة .لذلك قمنا بدراسة 65 مريض لديهم احتشاءات فجوية في قسم الأمراض العصبية في مشفى تشرين الجامعي في اللاذقية و 65 شاهد في الفترة الممتدة بين أيار 2017 حتى أيار 2018 . الطرائق : لقد حصلنا على عوامل الخطورة عند المرضى بواسطة استبيان منظم و قمنا بتسجيل العمر ، الجنس ، ضغط الدم ، السكر ، وجود أمراض قلبية ، التدخين ، الكحول ، التمارين الرياضية عند المرضى و الشهود . كما قمنا بإجراء تحاليل مخبرية و ECG و أيكو قلب و CT دماغ أو MRI دماغ . النتائج: لوحظ زيادة الاحتشاءات الفجوية عند المرضى الذين لديهم ارتفاع توتر شرياني (P-value=0.0001) و (OR=9.9) ، المدخنين (P-value=0.002) و (OR=5.2) ، و مرضى الداء السكري (P-value=0.001) و (OR=5.3) ، بينما كان هناك نقص في حدوث الاحتشاءات الفجوية لدى الرياضيين (0.002P-value=) و (OR=2.6) . لم يكن هناك خطر لحدوث الاحتشاءات الفجوية عند المرض الذين لديهم أمراض قلبية (P-value=0.6) و (OR=0.8) ، فرط كولسترول الدم (P-value=1) و (OR=1)، الكحوليين (P-value=0.7) و (OR=0.8) . الاستنتاج : المرضى الذين لديهم فرط توتر شرياني أو داء سكري أو المدخنين أو الذين ليس لديهم أمراض قلبية يملكون خطر عالٍ للاحتشاءات الفجوية ، بينما الذين يمارسون التمارين الرياضية بشكل مستمر هم أقل خطر لحدوث الاحتشاءات الفجوية .
Purpose: Lacunar infarcts is an important stroke subgroup with unique clinical and pathologic features, but risk factors for lacunar infarcts have been rarely documented. To address this matter, we studied 65 patients had lacunar infarction at Department of Neurology , Tishreen University Hospital , Lattakia , Syria , and 65 controls during the period between May 2017 – May 2018 . Methods: We obtained information concerning risk factor exposure status among the patients by a structured questionnaire , we recorded age , sex , blood pressure , glucose , heart diseases , cigarette smoking , alcohol drinking , physical exercise for patiens and controls .We do laboratory tests and ECG and echocardiography and CT brain or MRI . Results: Significantly increasing the risk of lacunar stroke were hypertension (P-value=0.0001) and (OR=9.9), Current smokers (P-value=0.002) and (OR=5.2), diabetes (P-value=0.001) and (OR=5.3) , whereas frequent physical exercise was associated with a significantly decreased risk) P-value=00001( and (OR=2.6). There was no risk of lacunar stroke associated with heart disease (P-value=0.6) (OR=0.8) , high cholesterol (Pvalue= 1) and (OR=1) , alcohol drinking (P-value=0.7) and (OR=0.8). Conclusions: Patients with hypertension or diabetes, current smokers, those who have not heart disease, are at a higher risk of lacunar stroke, whereas those who undertake regular physical exercise may be at lower risk.
References used
MART-VILALTA JL, ARBOIX A, MOHR JP. Lacunes. In: Stroke. Pathophysiology, Diagnosis, and Management. Mohr JP, Choi DW, Grotta JC, Weir B, Wolf PhA (Eds). Churchill–Livingstone, PA, USA, 2004, 275–299
FISHER CM. Lacunar strokes and infarcts: a review. Neurology 32(8): 1982; 871-6
FISHER CM. Lacunes: Small, Deep Cerebral Infarcts. Neurology 15: 1965; 774-84
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coronary artery abnormalities in 20-25 percent of untreated children.
The aim of this study was to determine the type of heart lesion and the coron
ary risk factors and to
identify patients with high risk in order to take the necessary measures to reduces morbidity and
morbidity.
Materials & Methods: We studied 70 children, aged 3 month to 10 years, who met the criteria for the
diagnosis of KD, two thirds were males.
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were classified as follows: diffuse ectasia (5) cases 33.3%, coronary artery aneurysms 10 cases (66.6%).
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year or more than 5 years, male gender, fever lasting more than 10 days or recurrence of fever after an a
febrile period, lower hemoglobin, lower platelet count, higher white cell count , lower albumin level and
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months in approximately 60% of patients where (6) aneurysms regressed spontaneously and the two large
aneurysms became smaller. One patient with giant aneurysm had developed coronary stenosis and needed
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aneurysms were resolved at follow up of 2-3 years.
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Aim: Identifying the different risk factors for CIN .
Methods: This is a prospective analytical study
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level equal or more than 25% from baseline values within 48-72 hours after the coronary
procedure.
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