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Skin tags are common benign skin tumors usually occurring on the neck and major flexors of older people. Objective: To investigate and compare the prevalence of diabetes and disorders of triglycerides, cholesterol, LDL, and HDL levels in patients wit h skin tags and a control group. A case-control study was conducted in individuals between (25-70) years old, comparing cases (n=107) and age-, sex-matched controls (n=97) without skin tag. Cases and controls were recruited from patients consecutively seen at the outpatient dermatology clinic at Al-Assad University Hospital in Lattakia. All patients underwent standard laboratory tests of fasting blood sugar , triglycerides , cholesterol , LDL , and HDL levels. Results: Patients with skin tags had higher frequency of diabetes and higher levels of triglycerides , cholesterol , and LDL than the control group (P <=0.0001) and lower levels of HDL in patients with skin tags than the control group (P<=0.001). A positive correlation was found between the existing of skin tags and high BMI comparing with the control group (P<=0.0001). According to our results, skin tags might be a useful clinical sign that could alert clinicians to screen patients with skin tags for abnormal lipids, type 2 diabetes mellitus, and cardiovascular disease, and guide patients with skin tags to modify their life style, avoiding risk factors and making clinical laboratory check-up periodically
Blood glucose control reduces the microvascular and macrovascular complications in patients with diabetes mellitus type II. According to the American Diabetes Association, less than a half of those with diabetes achieve optimal control of blood gluc ose and target values of HbA1c. Life style modifications is one of the preferences of diabetes management because the potential relationship between diet and diabetic control. So nutrition therapy which given by dietitian and generally lifestyle modifications are considered mainly integrated to traditional medication for disease. The study included 104 patients with diabetes type II (HbA1c 8% ± 1.07, BMI 26.45 ± 2.69, fasting blood glucose 148.25 ± 33.76) given diabetes self-management education program and divided into two groups. The first group was treated with glibenclamide only and the second was treated with a combination of glibenclamide and metformin. After three months monitoring, 103 patients Completed the study. Therapeutic efficacy was evaluated considering HbA1c ≤ 6.5% as a target value. The necessary statistical study to analyze the data and evaluate the statistical significance of the results was made. The results indicate that the treatment supported with life style modifications was more effective than traditional therapy and patient education at blood glucose control in patients with diabetes mellitus type II and improve their health.
The diabetic foot ulcers considers a serious complications that related to diabetes, ulcers required medical and nursing care, that started with determine the degree of ulcer and applying Dressing which is from responsibility of nurses. There are man y kinds of dressing for grade 1&2 diabetic foot ulcers such as dry and honey dressing, aim of the study: Assessment the effect of applying the dry and honey dressings on the healing of grade (1&2) diabetic foot ulcers. Material and Methods: The study conducted in the Diabetes Mellitus Center in Lattakia city. A convenient sample of 40 adult diabetic patients whose meet the sample selection criteria were chosen. The sample divided randomly to two equal groups either the first group who subjected to dry dressing technique, or to the second group who subjected to honey dressing technique. Dressing changed for six weeks. Results: At the end of the study: (45%) of patients had complete ulcer healing, (35%) had partial healing and (20%) had no ulcer wound healing in the dry dressing group. Whereas (85%) of patients had complete ulcer healing and (15%) had partial healing. Conclusions: Honey dressing had statistical significant effects on the healing of grade (1&2) diabetic foot ulcers.
A known weight of Abrus seeds powder were soaked in cِhloroformmethanol (2:1) and extracted for 18 hours, the mixture then filtrated and reextracted with equal volume of water and evaporated to dryness. The crude extract is regarded as cِhloroform -methanol extract of Abrus Seeds (crab's eye). Chloroform-methanol extract was analyzed by HPLC and GC-MS chromatography for identification and purification of the extract components. Trigonelline and Abrine were isolated, a solution of a definite concentration was made from crab's eye extract and its pure components, trigonelline and Abrine, then oral administration of this solution of a definite concentration were given to the Alloxan diabetic rats.
Background: Diabetes mellitus is a leading public health problem with increasing incidence and long term complications. These complications are mainly a consequence of macro-vascular and microvascular damages of the target organs. The incidence of several pulmonary abnormalities during the course of Diabetes Mellitus because the presence of an extensive microvascular circulation and abundant connective tissue in the lungs , raises the possibility that lung tissue may be a target organ in diabetic patients. Objectives: This research is designed to study the impact of DM and both the duration of the disease and the glycemic control on pulmonary function tests. Methodology: This is a cross-sectional study carried out on 75 patients with type II diabetes mellitus patients at Tishreen University Hospital in the period between October 2015 and October 2016 .We compared with a control group consisted of 75 non diabetic healthy persons . Measurement of HbA1C , fasting plasma glucose (FPG) , and spirometry were made to all subjects and the following pulmonary function parameters were recorded: Forced Expiratory Volume in the first second (FEV1), Forced Vital Capacity (FVC), and Forced Expiratory Volume percent (FEV1/ FVC%) . Results were analyzed by calculating Mean ± SD, using X2 test , Karl Pearson correlation and ANOVA test. Results: The mean FEV1, FVC, FEV1/FVC% values were low in diabetics (p value <0.05) compared to healthy non-diabetics (control group). Also, uncontrolled diabetics show a greater decrease in these values than controlled diabetics. There was a greater decrease in these values in patients with long period of disease . Conclusion: The findings of the present study suggest that, the lung is a target organ for damage in DM and diabetics show a decrease in PFTs with a restrictive pattern lesion compared with non-diabetics . And this deterioration is exaggerated in uncontrolled diabetics and with the long duration of DM .
introduction: Diabetes mellitus is a global epidemic and a leading cause for increasing mortality and morbidity. Although prevention and care policies exist, diabetes continues to be a global public health problem with serious consequences. Aim: To assess the educational needs on diabetes among patients, level of knowledge and patient specific characteristics that are associated with this knowledge. Method: A descriptive study was conducted among 50 patients who entered Tishreen university between May 2017 and December 2017. Questionnaire on different domains of diabetes such as general knowledge, complications, treatment, life style, symptoms and prevention. Each statement was given a score of one if it was answered correctly and zero for a wrong answer. Out of a total score, a score of seventy percent and above was considered good knowledge , between thirty percent and seventy considered moderate, less than thirty considered poor knowledge . Results: more than half, were > 50 years (54%), (54%) were males, 46% were female. Most of educational needs were: regarding of insulin, its kinds, sides effects, methods of prevention of diabetic foot and care it. The level of knowledge of diabetes was moderate 63%. Recommendation: Awareness regarding all the aspects of diabetes mellitus needs to be increased for better control of the disease and its complications. Future studies about effect of education program on improvement of knowledge and self care, especially about the diabetic foot.
Purpose: Lacunar infarcts is an important stroke subgroup with unique clinical and pathologic features, but risk factors for lacunar infarcts have been rarely documented. To address this matter, we studied 65 patients had lacunar infarction at Depa rtment of Neurology , Tishreen University Hospital , Lattakia , Syria , and 65 controls during the period between May 2017 – May 2018 . Methods: We obtained information concerning risk factor exposure status among the patients by a structured questionnaire , we recorded age , sex , blood pressure , glucose , heart diseases , cigarette smoking , alcohol drinking , physical exercise for patiens and controls .We do laboratory tests and ECG and echocardiography and CT brain or MRI . Results: Significantly increasing the risk of lacunar stroke were hypertension (P-value=0.0001) and (OR=9.9), Current smokers (P-value=0.002) and (OR=5.2), diabetes (P-value=0.001) and (OR=5.3) , whereas frequent physical exercise was associated with a significantly decreased risk) P-value=00001( and (OR=2.6). There was no risk of lacunar stroke associated with heart disease (P-value=0.6) (OR=0.8) , high cholesterol (Pvalue= 1) and (OR=1) , alcohol drinking (P-value=0.7) and (OR=0.8). Conclusions: Patients with hypertension or diabetes, current smokers, those who have not heart disease, are at a higher risk of lacunar stroke, whereas those who undertake regular physical exercise may be at lower risk.
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