This study tries to assess the potential anti-atherosclerotic role of adiponectin. It includes 54 patients at Al-Assad University Hospital in Lattakia, who are candidates for catheterization, and control group of 25 individuals.
Serum adiponectin
levels have been measured in both groups, and levels of hs-CRP have been also measured in both groups and compared with adiponectin levels. Catheterization has been done to the patients group and the results of angiography are categorized to mild, moderate, and severe coronary artery disease (CAD) according to the SYNTAX SCORE
The study concludes that serum adiponectin levels are higher in patients with mild CAD(23.86 μg/ml) compared to patients with moderate to severe CAD (13.62 μg/ml);(p=0.001<0.05). The average serum adiponectin levels in control group was (17.1μg/ml). There was no statistically significant of the relation between the concentration of hs-CRP and the concentration of adiponectin .However, there was a statistically significant difference between the average concentration of hs-CRP in the patients group (7.1 mg/l) and the control group (2.7 mg/l); (P=0.003<0.05).
Background: primary percutaneous coronary intervention PCI is the treatment of
choice in civilized countries for acute myocardial infarction, the aim of the treatment here
is the revascularization as soon as possible. Patients and methods: it is re
trospective study
of 133 patients of acute MI have been divided into two subgroups. The first subgroup has
been treated with streptokinase infusion, and the other subgroup has beet treated by PCI.
We monitored the patients within hospitalization , reinfarction, mortality, cardiogenic
shock, heart failure, also we recorded the time needed to apply the method of treatment and
Timi score by diagnostic cardiac catheterization after applying the treatment.
Aim of study: to compare between streptokinase and PCI in our hospitals to know
which way is better in which we can give the best medical care for this critical patients.
Results: 63 patients undergo to pci and 70 patients undergo to streptokinase therapy.
Streptokinase group had higher rates in mortality for noncardiac reasons 100%,
cardiogenic shock 60% , reinfarction 81%, mortality for cardiac reasons 80%, while it was
faster in applying the treatment and equal to pci in timi score. While pci group has higher
rated in hospitalization for cardiac reasons 70% and in cases that has new congestive heart
failure 63%, and nearly equal to streptokinase group in timi score.
Conclusion: pci was better in mortality and cardiogenic shock and reinfarction than
streptokinase but it was worse in hospitalization for cardiac reasons and congestive heart
failure cases . pci was too late than streptokinase in applying the treatment . we notice that
the two methods of treatment was nearly equal in timi score.
Prevention is the key to reduce the incidence of Contrast-induced nephropathy (CIN) and it
begins with identification of the high risk patients.
Aim: Identifying the different risk factors for CIN .
Methods: This is a prospective analytical study
that has included 156 patients, all
underwent an objective exam, hematochemical measurements. The patiemts were divided
into two groups depending on the incidence of CIN defined as an increase in creatinine
level equal or more than 25% from baseline values within 48-72 hours after the coronary
procedure.
Results: Several independent risk factors for CIN were identified: age equal or more 70
year (OR:4.11, P:0.004( , contrast volume more than 200 ml )OR:3.2,P:0.01(, anemia
(OR:2.7,P:0.01), urgent cardiac catheterization) OR:3.3,P:0.02(,diabetic nephropathy
(OR:4.9,P:0.04).
Conclusion: . Increased contrast volume ,urgent cardiac catheterization elderly patients ,
anemia and diabetic nephropathy are associated with increased risk for CIN.
