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Register a new userRisk factors for contrast induced nephropathy among patients undergoing coronary angiography or percutaneous coronary intervention
عوامل الخطر لاعتلال الكلية المحدث بالمادة الظليلة عند مرضى تصوير الأوعية الإكليلية الظليل و التداخل الإكليلي
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Tishreen University ورقة بحثية
Publication date
2018
fields
Medicine
and research's language is
العربية
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Shamra Editor
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الوقاية هي الأساس في تقليل نسبة حدوث اعتلال الكلية المحدث بالمادة الظليلة (CIN) و تبدأ بالتعرف على المرضى ذوي الخطورة العالية. الهدف: التعرف على عوامل الخطر المختلفة لحدوث CIN عند مرضى تصوير الأوعية الإكليلية الظليل و التداخل الإكليلي. المواد و الطرق: دراسة مستقبلية تحليلية شملت 156 مريضاً أُحذت لهم قصة مرضية مع تقييم مخبري و صُنفوا لمجموعتين تبعاً لحدوث CIN الذي عُرف بحدوث ارتفاع في قيمة كرياتينين المصل بعد 48-72 ساعة من القثطرة القلبية بمقدار 25% أو أكثر من القيمة الأساسية قبل الإجراء. النتائج: تم التعرف على عدة عوامل خطر مستقلة لحدوث CIN:العمر 70 سنة أو أكثر (OR:4.11, P:0.004), كمية المادة الظليلة > 200 مل (OR:3.2,P:0.01), فقر الدم (OR:2.7,P:0.01), القثطرة القلبية العاجلة (OR:3.3,P:0.02), اعتلال الكلية السكري (OR:4.9,P:0.04). الخلاصة: تحمل القثطرة القلبية العاجلة و زيادة كمية المادة الظليلة و المرضى المسنون و المصابون بفقر الدم و مرضى اعتلال الكلية السكري خطورة اكبر لحدوث CIN.
Prevention is the key to reduce the incidence of Contrast-induced nephropathy (CIN) and it begins with identification of the high risk patients. Aim: Identifying the different risk factors for CIN . Methods: This is a prospective analytical study that has included 156 patients, all underwent an objective exam, hematochemical measurements. The patiemts were divided into two groups depending on the incidence of CIN defined as an increase in creatinine level equal or more than 25% from baseline values within 48-72 hours after the coronary procedure. Results: Several independent risk factors for CIN were identified: age equal or more 70 year (OR:4.11, P:0.004( , contrast volume more than 200 ml )OR:3.2,P:0.01(, anemia (OR:2.7,P:0.01), urgent cardiac catheterization) OR:3.3,P:0.02(,diabetic nephropathy (OR:4.9,P:0.04). Conclusion: . Increased contrast volume ,urgent cardiac catheterization elderly patients , anemia and diabetic nephropathy are associated with increased risk for CIN.
References used
Barrett,B; Parfrey,P. Prevention of nephrotoxicity induced by radiocontrast agents. The New England Journal of Medicine, vol. 331, no. 21, 1994 , 1449–1450
Detrenis,S; Meschi,M; Musini,S; Savazzi,G. Lights and shadows on the pathogenesis of contrast-induced nephropathy: state of the art. Nephrol Dial Transplant. 2005,20:1542
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The aim of this study is to investigate the potential role of previous
Chlamydia Pneumoniae Infection on restenosis rate after Percutaneous
Transluminal Coronary balloon angioplasty.
Our data didn’t confirm the relationship between prior Chlamydia
Pneumoniae Infection and restenosis after PTCA. The results didn’t
support the use of antibiotics before or after PTCA to reduce the restenosis
after PTCA.
Purpose: Lacunar infarcts is an important stroke subgroup with unique clinical and
pathologic features, but risk factors for lacunar infarcts have been rarely documented. To
address this matter, we studied 65 patients had lacunar infarction at Depa
rtment of
Neurology , Tishreen University Hospital , Lattakia , Syria , and 65 controls during the
period between May 2017 – May 2018 .
Methods: We obtained information concerning risk factor exposure status among the
patients by a structured questionnaire , we recorded age , sex , blood pressure , glucose ,
heart diseases , cigarette smoking , alcohol drinking , physical exercise for patiens and
controls .We do laboratory tests and ECG and echocardiography and CT brain or MRI .
Results: Significantly increasing the risk of lacunar stroke were hypertension
(P-value=0.0001) and (OR=9.9), Current smokers (P-value=0.002) and (OR=5.2), diabetes
(P-value=0.001) and (OR=5.3) , whereas frequent physical exercise was associated with a
significantly decreased risk) P-value=00001( and (OR=2.6). There was no risk of
lacunar stroke associated with heart disease (P-value=0.6) (OR=0.8) , high cholesterol (Pvalue=
1) and (OR=1) , alcohol drinking (P-value=0.7) and (OR=0.8).
Conclusions: Patients with hypertension or diabetes, current smokers, those who
have not heart disease, are at a higher risk of lacunar stroke, whereas those who undertake
regular physical exercise may be at lower risk.
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on, ventricular arrhythmias and sudden cardiac death. Lack of angiographic recognition from clinicians is a major factor of under-diagnosis. With the advent of new imaging modalities, particularly with intracoronary imaging, there has been improved diagnosis of SCAD. The aim of this paper is to review the epidemiology, etiology, presentation, diagnosis and management of SCAD.
This study was preformed to evaluate early results of Stenting PTCA by
determinig complications in the first 24 hrs after Stenting PTCA, we excluded
patients without stents.
Stenting PTCA was performed to 60 patients between 31/8/1998 and 31/2/199
9
and we monitored patients for 24 hrs.
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