Skin tags are common benign skin tumors usually occurring on the neck and major flexors of older people. Objective: To investigate and compare the prevalence of diabetes and disorders of triglycerides, cholesterol, LDL, and HDL levels in patients wit
h skin tags and a control group. A case-control study was conducted in individuals between (25-70) years old, comparing cases (n=107) and age-, sex-matched controls (n=97) without skin tag. Cases and controls were recruited from patients consecutively seen at the outpatient dermatology clinic at Al-Assad University Hospital in Lattakia. All patients underwent standard laboratory tests of fasting blood sugar , triglycerides , cholesterol , LDL , and HDL levels.
Results: Patients with skin tags had higher frequency of diabetes and higher levels of triglycerides , cholesterol , and LDL than the control group (P <=0.0001) and lower levels of HDL in patients with skin tags than the control group (P<=0.001). A positive correlation was found between the existing of skin tags and high BMI comparing with the control group (P<=0.0001).
According to our results, skin tags might be a useful clinical sign that could alert clinicians to screen patients with skin tags for abnormal lipids, type 2 diabetes mellitus, and cardiovascular disease, and guide patients with skin tags to modify their life style, avoiding risk factors and making clinical laboratory check-up periodically
The role of Interleukin-1 genes in the association between chronic periodontitis
and atherosclerosis has been under debate. The purpose of this study is to compare the existence of
interleukin1 genes polymorphism in the chronic periodontitis subjects with and without atherosclerosis.
