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هرمية الداء السكري أثناء الحمل
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يعد الداء السكري الاضطراب الغدي الأكثر شيوعا الذي يحدث أثناء الحمل. و إن نسبة انتشاره تزداد و في كل أنحاء العالم. و نتيجة لتأثير الداء السكري على كل من الأم و الجنين فهو يعد موضوعا جديرا بالدراسة. هدف البحث و مبرراته: تحديد معدل انتشار الداء السكري أثناء الحمل للتأكيد على اختبارات المسح في الكشف عن الداء السكري أثناء الحمل. مواد البحث و طرائقه: النتائج: شملت الدراسة 760حاملا من مراجعات قسم التوليد و أمراض النساء في مشفى الأسد الجامعي في اللاذقية خلال الفترة الممتدة من حزيران 2013 حتى كانون الأول 2014, حيث تم استجواب المريضات و تسجيل المعلومات المتعلقة بكل من عمر الحامل و العمر الحملي و مشعر الكتلة، إضافة للاختبارات اللازمة لتشخيص الداء السكري أثناء الحمل. 73 حاملا حققت معايير إيجابية لتشخيص الداء السكري.
Gestational Diabetes Mellitus (GDM) is one of the most common complications during pregnancy. The prevalence of gestational diabetes (GDM) is increasing all over the world. Hence, the impact of GDM on maternal and infant health is an important topic of research. Objective: The aim of the study was to determine the prevalence of GDM, and to assess the impact of universal screening to detect Gestational diabetes mellitus. Subjects and methods: A representative sample of 760 pregnant women who attended the antenatal department of Al Assad Hospital in Lattakia were surveyed during the period from June 1st, 2013 to December 1st, 2014. The questionnaire covered variables related maternal age, gestational age, BMI, and women underwent the diagnostic tests for GDM. 73 pregnant women had positive results.
References used
GETAHUN,D.; NATH,C.; ANANTH,C.V.; CHAVEZ,M.R.; SMULIAN,J.C. Gestational diabetes in the United States: temporal trends 1989 through 2004. Am J Obstet Gynecol, 2008,VOL 198,e5,s:525
AMERICAN DIABETES ASSOCIATION. Diagnosis and Classification of Diabetes Mellitus. Diabetes Care, 2013, VOL36, SUPPL.1:S 71
MOKDAD,A.H.; FORD,E.S.; BOWMAN,B.A.; ET AL. Diabetes trends in the US: 1990-1998. Diabetes Care, 2000, 23:1278-1283
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This study examined 64 patients who visited The New Maternity Hospital at
Damascus University. Those patients were divided almost equally between the
three types of diabetes.
Blood sugar was well controlled by : Diet in 20.3%, insulin in 70.3% and
9.4% of
patients reported or came at delivery; So they recieved no treatment.
The results were:
1. Obesity was the major combined risk factor among all patients.
2. The ideal time to deliver patients was between 38-40 weeks, the rate of
stillbirth rises sharply when patients passe their EDD.
3. The rate of cesarean sections rose to 60.9% in diabetic patients compared to
15.8% in non diabetic patients.
4. Perinatal Morbidity and mortality rose (16 0% Vs 7.7 0%) due to increase
in rate of congenital anomalies (7.8% Vs 2%) also due to macrosomia
(21.3%) associated with immaturity leading to failure of the newborn to
adapt with extra-uterine life.
Clinicians are occasionally faced with the dilemma of
managing pregnant patients who require ongoing anticoagulation.
Examples include women with mechanical heart valves, venous
thromboembolism, and chronic atrial fibrillation.
Methods : A prospe
ctive study randomly assigned 33 pregnant women aged
between 22 and 43 years (average; 28.4); to receive either fractionated
heparin: Enoxaparin (The 1st group, n = 17) or unfractionated heparin (The
second group, n=16).
In both groups, patients were given heparin (fractionated or unfractionated)
during the 1st trimester and last month of pregnancy, and took warfarin
between the 4th and 8th month.
Background: Diabetes mellitus is a leading public health problem with increasing
incidence and long term complications. These complications are mainly a consequence of
macro-vascular and microvascular damages of the target organs. The incidence of
several
pulmonary abnormalities during the course of Diabetes Mellitus because the presence of
an extensive microvascular circulation and abundant connective tissue in the lungs , raises
the possibility that lung tissue may be a target organ in diabetic patients.
Objectives: This research is designed to study the impact of DM and both the
duration of the disease and the glycemic control on pulmonary function tests.
Methodology: This is a cross-sectional study carried out on 75 patients with type II
diabetes mellitus patients at Tishreen University Hospital in the period between October
2015 and October 2016 .We compared with a control group consisted of 75 non diabetic
healthy persons . Measurement of HbA1C , fasting plasma glucose
(FPG) , and spirometry were made to all subjects and the following pulmonary function
parameters were recorded: Forced Expiratory Volume in the first second (FEV1), Forced
Vital Capacity (FVC), and Forced Expiratory Volume percent (FEV1/ FVC%) . Results
were analyzed by calculating Mean ± SD, using X2 test , Karl Pearson correlation and
ANOVA test.
Results: The mean FEV1, FVC, FEV1/FVC% values were low in diabetics (p value
<0.05) compared to healthy non-diabetics (control group). Also, uncontrolled diabetics
show a greater decrease in these values than controlled diabetics. There was a greater
decrease in these values in patients with long period of disease .
Conclusion: The findings of the present study suggest that, the lung is a target organ
for damage in DM and diabetics show a decrease in PFTs with a restrictive pattern lesion
compared with non-diabetics . And this deterioration is exaggerated in uncontrolled
diabetics and with the long duration of DM .
Background: Diabetes mellitus type2 (T2DM) and thyroid dysfunction (TD) are the
two most common endocrine disorders in clinical practice. The unrecognized TD may
adversely affect the metabolic control and add more risk to an already predisposing
s
cenario for cardiovascular diseases. The objective of this study was to investigate the
prevalence of TD in patients with type2 diabetes mellitus.
Objective: To determine the prevalence and patterns of thyroid dysfunction in
patients with type2 diabetes mellitus.
Material and methods: Study included total 362 subjects (204 type2 diabetic patients
and 158 healthy non diabetic subjects). Agroup of type2 diabetic patients and control group
were evaluated for thyroid dysfunction by testing TSH and FT4 when TSH was abnormal.
The correlation of prevalence of thyroid disorder with gender distribution, age distribution,
duration of diabetes, BMI, treatment, fasting plasma glucose (FPG), serum triglyceride and
serum cholesterol was then done in diabetic patients. The observations and interpretations
were recorded and results obtained were statistically analyzed.
Results: The prevalence of thyroid dysfunction among type2 diabetic patients was
found to be 13,2%. In the control group, the prevalence of thyroid dysfunction was 6,3%.
There was a significant difference between diabetics and control subjects p= 0,031.The
most frequently TD in type2 diabetic patients was subclinical hypothyroidism (8,3%).
Thyroid dysfunction was significantly correlated with gender (women > man), age < 60
years, FPG > 130mg/dl, TG > 150mg/dl and insulin treatment in type2 diabetic patients.
Conclusion: Screening of thyroid dysfunction shoud be done in all Type2 diabetic
patients.
This research was done as a collaboration work between Tishreen University and the
General Commission for Scientific Agricultural Research in Karahta research station for
improvement of Shami goats and Der Al-Hajar station to set tables for normal
values of
some blood and chemical parameters in Awassi sheep during pregnancy to predict any
nutrition or health disorders. Forty seven Awassi ewes in the same age (in the third season)
were used for that purpose. Blood sample were collected from all ewes every month of the
pregnancy period. Thealanine aminotransferase (ALT),the aspartate aminotransferase
(AST), the alkaline phosphatase (ALP), the glucose (Glu) were analyzed.
Results indicated the existence of significant changes (P<0.05) between the
increase and decrease in all indicators studied throughout The study period, which shows
the change in functional status of liver in conjunction with stage of pregnancy.The overall
average of the effectiveness of enzymes (2.05-26.47), (32.65-181.40) and (11.17-79.76)
U/l for each of the ALP, ALT and AST, respectively, and total concentration of glucose
(37,50-95.20 mg/dl) throughout the study period.
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