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دراسة العلاقة بين الزنمات واستقلاب السكر والشحوم عند مراجعي مشفى الأسد الجامعي
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الزنمات الجلدية عبارة عن أورام جلدية سليمة شائعة تحدث عادةً على العنق والثنيات الرئيسة عند البالغين. الهدف تحري ومقارنة معدل انتشار الداء السكري, واضطراب شحوم الدم والكوليسترول وقيم الـ LDL والـ HDL عند مرضى الزنمات ومجموعة الشاهد. أجريت دراسة مقارنة (حالة – شاهد) عند أفراد بعمر بين(25 - 70) سنة، ومقارنة 107 حالات عندهم زنمات, بنفس العمر ونفس الجنس مع مجموعة شاهد مكونة من 97 فرداً بدون زنمات. تم انتقاء الحالات والشواهد من المرضى مراجعي العيادة الجلدية في مشفى الأسد الجامعي باللاذقية. خضع كل المرضى لمعيار القيم المخبرية لسكر الدم على الريق والشحوم الثلاثية والكوليسترول والـ LDL والـ HDL. النتائج: وجد لدى مرضى الزنمات تواترٌ أعلى لحدوث الداء السكري وارتفاع في شحوم الدم والكوليسترول وقيم الـ LDL مقارنةً بمجموعة الشاهد (p≤0.0001).وانخفاض قيم الـ HDL عند مرضى الزنمات مقارنةً بمجموعة الشاهد (p≤0.001).كما وجد ارتباط إيجابي بين وجود الزنمات وارتفاع مشعر كتلة الجسم مقارنةً بمجموعة الشاهد (P≤0.0001). بالاعتماد على نتائج دراستنا تبين أن الزنمات الجلدية قد تكون علامة سريرية مفيدة يمكن أن تنبه الأطباء السريريين لضرورة تحري اضطراب شحوم الدم والداء السكري نمط 2 وحدوث الداء القلبي الوعائي عند مرضى الزنمات، وتوجيه مريض الزنمات لتعديل نمط حياته، من حيث تجنب عوامل الخطورة الآنفة الذكر وإجراء الفحوص المخبرية والسريرية بصورة دورية
Skin tags are common benign skin tumors usually occurring on the neck and major flexors of older people. Objective: To investigate and compare the prevalence of diabetes and disorders of triglycerides, cholesterol, LDL, and HDL levels in patients with skin tags and a control group. A case-control study was conducted in individuals between (25-70) years old, comparing cases (n=107) and age-, sex-matched controls (n=97) without skin tag. Cases and controls were recruited from patients consecutively seen at the outpatient dermatology clinic at Al-Assad University Hospital in Lattakia. All patients underwent standard laboratory tests of fasting blood sugar , triglycerides , cholesterol , LDL , and HDL levels. Results: Patients with skin tags had higher frequency of diabetes and higher levels of triglycerides , cholesterol , and LDL than the control group (P <=0.0001) and lower levels of HDL in patients with skin tags than the control group (P<=0.001). A positive correlation was found between the existing of skin tags and high BMI comparing with the control group (P<=0.0001). According to our results, skin tags might be a useful clinical sign that could alert clinicians to screen patients with skin tags for abnormal lipids, type 2 diabetes mellitus, and cardiovascular disease, and guide patients with skin tags to modify their life style, avoiding risk factors and making clinical laboratory check-up periodically
References used
Demir S, et al: Acrochordon and impaired carbohydrate metabolism. Acta Diabetol 2002;39:57
Banik R, Lubach D. Skin tags: localization and frequencies according to sex and age. Dermatologica.4111;174:180-3
Habif: Clinical Dermatology, 4th ed.Copyright © 2004 Mosby, Inc.p456
Kahana M, Grossman E, Feinstein A, et al. Skin tags: a cutaneous marker for diabetes mellitus. Acta Derm Venereol. 4111;67:175-7
Goodheart HP. Surgical pearl: a rapid technique for destroying small skin tags and filiform warts. Dermatol Online J 2003;9:34
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The study included 77 patients admitted to Pediatric Department in AL-ASSAD
University Hospital in Lattakia for doing therapeutic gastroendoscopy between ( Jul
2009-Jul 2014),number of procedures were (195) with age ranging between( 1mon-16 y)
and
The main indication of interventional GI endoscopy in this series was foreign body
extractions, oesophageal stenosis, esophageal varices ligation followed by polyp resection
and Management of rectal prolapse refractory.
-There were" not any complications during therapeutic procedures (94%), and
complet cure percent was high (64,4%), but (26%) of cases are followed up and good
until now, there were Two patients of oesophageal dilatation may need surgical
interference.
The empty sella syndrome (ESS) is an asymptomatic radiological syndrome,
affecting 6% of post-menopausal women and can be seen in all ages.
The results were similar with other studies in many respects, such as a wide
age spectrum including childre
n, and the occurrence of diabetes insipidus in
5.97%.
The results of our study were discordant with other studies with respect to
hyperprolactinemia which reached 58.2% in our study (in other studies did
not exceed 33.7%). No concurrent cases of secretory pituitary adenomas
were found (studies refer to an incidence of acromegaly and Cushing’s
syndrome in 2.6% of ESS for each). We did not record CSF rhinorrhea nor
were visual disturbances seen in our cohort. Patients received symptomatic
treatment and none were referred to surgery.
Introduction 7 Visceral Leishmaniasis( VL )is characterized by a spectrum of
clinical features, with high cure rates in early diagnosis.
Objective: the objective is to describe the clinical and epidemiological features and
laboratory variables of
children with visceral leishmaniasis ,And to define the importance
of a positive direct investigation of the parasite in Bone marrow in the diagnosis of disease
.
Patients and Methods : It was a case series study of )52( cases of Visceral
Leishmaniasis which were hospitalized between June-20 31and June-2014 in Al -Assad
University Hospital ,Latakia
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presented with fever ,common findings in physical examination were(100%) Pallor and
(97%) splenomegaly
The direct investigation of parasite in Bone marrow was positive in )%55( of cases .
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and EUCAST for ESBL.
75 (32%)of total isolates demonstrated MDR (multi drug resistance),62 of resistant bacteria (26% of total) were determined as ESBL producers.
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