Do you want to publish a course? Click here

Life style modification and its role in Controlling Diabetes Mellitus type 2 in Syria

تعديل نمط الحياة ودوره في ضبط الداء السكري من النمط الثاني في سورية

1958   3   18   0 ( 0 )
 Publication date 2014
and research's language is العربية
 Created by Shamra Editor




Ask ChatGPT about the research

Blood glucose control reduces the microvascular and macrovascular complications in patients with diabetes mellitus type II. According to the American Diabetes Association, less than a half of those with diabetes achieve optimal control of blood glucose and target values of HbA1c. Life style modifications is one of the preferences of diabetes management because the potential relationship between diet and diabetic control. So nutrition therapy which given by dietitian and generally lifestyle modifications are considered mainly integrated to traditional medication for disease. The study included 104 patients with diabetes type II (HbA1c 8% ± 1.07, BMI 26.45 ± 2.69, fasting blood glucose 148.25 ± 33.76) given diabetes self-management education program and divided into two groups. The first group was treated with glibenclamide only and the second was treated with a combination of glibenclamide and metformin. After three months monitoring, 103 patients Completed the study. Therapeutic efficacy was evaluated considering HbA1c ≤ 6.5% as a target value. The necessary statistical study to analyze the data and evaluate the statistical significance of the results was made. The results indicate that the treatment supported with life style modifications was more effective than traditional therapy and patient education at blood glucose control in patients with diabetes mellitus type II and improve their health.


Artificial intelligence review:
Research summary
تتناول الدراسة التي أجرتها الباحثة الصيدلانية فرح هاشم عمران تأثير تعديل نمط الحياة على ضبط الداء السكري من النمط الثاني في سوريا. تشير الدراسة إلى أن ضبط غلوكوز الدم بشكل محكم يقلل من اختلاطات الأوعية الدموية الصغيرة والكبيرة لدى مرضى السكري. تم تقسيم 104 مرضى إلى مجموعتين: الأولى تعالج بالغليبنكلاميد فقط، والثانية تعالج بمشاركة الغليبنكلاميد مع الميتفورمين. بعد متابعة لمدة ثلاثة أشهر، أظهرت النتائج أن تعديل نمط الحياة وتثقيف المرضى لهما دور كبير في تحسين ضبط غلوكوز الدم وتحسين الحالة العامة للمرضى. تم تقييم الفعالية العلاجية باستخدام مقايسة الخضاب الغلوكوزي HbA1c واعتماد القيمة < 6.5% كقيمة هدف. أظهرت النتائج أن المعالجة المدعومة بتعديل نمط الحياة كانت أكثر فعالية من العلاج التقليدي في ضبط غلوكوز الدم وتحسين صحة المرضى بشكل عام. الدراسة تؤكد على أهمية التغذية العلاجية والنشاط البدني كجزء من إدارة مرض السكري.
Critical review
تعد هذه الدراسة خطوة مهمة في فهم تأثير تعديل نمط الحياة على ضبط الداء السكري من النمط الثاني. ومع ذلك، هناك بعض النقاط التي يمكن تحسينها. أولاً، كان من الممكن أن تكون الدراسة أكثر شمولية إذا تم تضمين مجموعة أكبر من المرضى ومن مختلف المناطق الجغرافية في سوريا. ثانياً، لم يتم تناول تأثير العوامل النفسية والاجتماعية على التزام المرضى بتعديل نمط حياتهم، وهو جانب مهم يمكن أن يؤثر على النتائج. ثالثاً، كان من الأفضل تضمين فترة متابعة أطول لتقييم الاستدامة الطويلة الأمد للتغييرات في نمط الحياة. وأخيراً، كان من الممكن توضيح المزيد من التفاصيل حول البروتوكولات الغذائية والرياضية المستخدمة لتكون الدراسة أكثر شفافية وقابلة للتكرار.
Questions related to the research
  1. ما هو الهدف الرئيسي من الدراسة؟

    الهدف الرئيسي من الدراسة هو مقارنة تأثير تعديل نمط الحياة على فعالية استراتيجيتين علاجيتين معتمدتين عالمياً لتدبير الداء السكري من النمط الثاني في سوريا.

  2. ما هي المعايير المستخدمة لتقييم الفعالية العلاجية في الدراسة؟

    تم تقييم الفعالية العلاجية باستخدام مقايسة الخضاب الغلوكوزي HbA1c واعتماد القيمة < 6.5% كقيمة هدف.

  3. ما هي النتائج الرئيسية التي توصلت إليها الدراسة؟

    أظهرت النتائج أن المعالجة المدعومة بتعديل نمط الحياة وتثقيف المرضى كانت أكثر فعالية من العلاج التقليدي في ضبط غلوكوز الدم وتحسين صحة المرضى بشكل عام.

  4. ما هي التوصيات التي قدمتها الدراسة بناءً على النتائج؟

    توصي الدراسة بأهمية تضمين تعديل نمط الحياة والتغذية العلاجية والنشاط البدني كجزء من إدارة مرض السكري لتحسين ضبط غلوكوز الدم والحالة الصحية العامة للمرضى.


References used
Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care. Jan 2003;26 Suppl 1:S5-20
Pittas A.pathophysiology of endocrinology, diabetes and metabolism. open course ware – tufts university.2005
Lebovitz H .Therapy for Diabetes Mellitus and Related Disorders. American Diabetes Association. June 2009;660-65
American Diabetes Association. Nutrition recommendations and interventions for diabetes: a position statement of the American Diabetes Association. Diabetes Care. 2008;31:S61-S78
Wing RR, Lang W, Wadden TA, Safford M, Knowler WC, Bertoni AG, et al. Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with type 2 diabetes. Diabetes Care. Jul 2011;34(7):1481-6
rate research

Read More

Type 2 Diabetes mellitus T2DM has been suggested to be the most common metabolic disorder associated with magnesium deficiency which has many adverse outcomes. The aim of this study was to evaluate plasma Mg in 126 T2DM patients recruited from Dia betes Centre in Lattakia, compare them to 70 healthy individuals, and assess the correlation between plasma Mg and HbA1c as a glycemic control biomarker. Magnesium was measured using xylidyl blue colorimetric method. HbA1c was measured using ion-exchange resin separation. The SPSS 19.0 software was used for statistical analysis. Mean plasma Mg concentrations of the diabetics was significantly lower than controls (P=0.0001). Plasma magnesium was negatively correlated with HbA1c (r=-0.5, P=0.0002). Plasma magnesium was below the normal reference range (1.9-2.5 mg/dL) in 47.6% of diabetics and 28.6% of controls. In conclusion, it is important to monitor Mg levels in both T2DM patients and non-diabetics and take procedures to correct hypomagnesaemia states.
This study aims to compare between two globally approved strategies to manage diabetes type II in Syria, by comparing their effectiveness in patients with diabetes type II who are treated in the national program of diabetes Clinics in Damascus and in vestigate their glucose control. The first strategy includes glibenclamide as a monotherapy and the second includes a combination of glibenclamide and metformin.
Background: Diabetes mellitus type2 (T2DM) and thyroid dysfunction (TD) are the two most common endocrine disorders in clinical practice. The unrecognized TD may adversely affect the metabolic control and add more risk to an already predisposing s cenario for cardiovascular diseases. The objective of this study was to investigate the prevalence of TD in patients with type2 diabetes mellitus. Objective: To determine the prevalence and patterns of thyroid dysfunction in patients with type2 diabetes mellitus. Material and methods: Study included total 362 subjects (204 type2 diabetic patients and 158 healthy non diabetic subjects). Agroup of type2 diabetic patients and control group were evaluated for thyroid dysfunction by testing TSH and FT4 when TSH was abnormal. The correlation of prevalence of thyroid disorder with gender distribution, age distribution, duration of diabetes, BMI, treatment, fasting plasma glucose (FPG), serum triglyceride and serum cholesterol was then done in diabetic patients. The observations and interpretations were recorded and results obtained were statistically analyzed. Results: The prevalence of thyroid dysfunction among type2 diabetic patients was found to be 13,2%. In the control group, the prevalence of thyroid dysfunction was 6,3%. There was a significant difference between diabetics and control subjects p= 0,031.The most frequently TD in type2 diabetic patients was subclinical hypothyroidism (8,3%). Thyroid dysfunction was significantly correlated with gender (women > man), age < 60 years, FPG > 130mg/dl, TG > 150mg/dl and insulin treatment in type2 diabetic patients. Conclusion: Screening of thyroid dysfunction shoud be done in all Type2 diabetic patients.
Background: Diabetes mellitus is a leading public health problem with increasing incidence and long term complications. These complications are mainly a consequence of macro-vascular and microvascular damages of the target organs. The incidence of several pulmonary abnormalities during the course of Diabetes Mellitus because the presence of an extensive microvascular circulation and abundant connective tissue in the lungs , raises the possibility that lung tissue may be a target organ in diabetic patients. Objectives: This research is designed to study the impact of DM and both the duration of the disease and the glycemic control on pulmonary function tests. Methodology: This is a cross-sectional study carried out on 75 patients with type II diabetes mellitus patients at Tishreen University Hospital in the period between October 2015 and October 2016 .We compared with a control group consisted of 75 non diabetic healthy persons . Measurement of HbA1C , fasting plasma glucose (FPG) , and spirometry were made to all subjects and the following pulmonary function parameters were recorded: Forced Expiratory Volume in the first second (FEV1), Forced Vital Capacity (FVC), and Forced Expiratory Volume percent (FEV1/ FVC%) . Results were analyzed by calculating Mean ± SD, using X2 test , Karl Pearson correlation and ANOVA test. Results: The mean FEV1, FVC, FEV1/FVC% values were low in diabetics (p value <0.05) compared to healthy non-diabetics (control group). Also, uncontrolled diabetics show a greater decrease in these values than controlled diabetics. There was a greater decrease in these values in patients with long period of disease . Conclusion: The findings of the present study suggest that, the lung is a target organ for damage in DM and diabetics show a decrease in PFTs with a restrictive pattern lesion compared with non-diabetics . And this deterioration is exaggerated in uncontrolled diabetics and with the long duration of DM .
comments
Fetching comments Fetching comments
Sign in to be able to follow your search criteria
mircosoft-partner

هل ترغب بارسال اشعارات عن اخر التحديثات في شمرا-اكاديميا