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Life style modification and its role in Controlling Diabetes Mellitus type 2 in Syria

تعديل نمط الحياة ودوره في ضبط الداء السكري من النمط الثاني في سورية

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 Publication date 2014
and research's language is العربية
 Created by Shamra Editor




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Blood glucose control reduces the microvascular and macrovascular complications in patients with diabetes mellitus type II. According to the American Diabetes Association, less than a half of those with diabetes achieve optimal control of blood glucose and target values of HbA1c. Life style modifications is one of the preferences of diabetes management because the potential relationship between diet and diabetic control. So nutrition therapy which given by dietitian and generally lifestyle modifications are considered mainly integrated to traditional medication for disease. The study included 104 patients with diabetes type II (HbA1c 8% ± 1.07, BMI 26.45 ± 2.69, fasting blood glucose 148.25 ± 33.76) given diabetes self-management education program and divided into two groups. The first group was treated with glibenclamide only and the second was treated with a combination of glibenclamide and metformin. After three months monitoring, 103 patients Completed the study. Therapeutic efficacy was evaluated considering HbA1c ≤ 6.5% as a target value. The necessary statistical study to analyze the data and evaluate the statistical significance of the results was made. The results indicate that the treatment supported with life style modifications was more effective than traditional therapy and patient education at blood glucose control in patients with diabetes mellitus type II and improve their health.


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Research summary
تتناول الدراسة التي أجرتها الباحثة الصيدلانية فرح هاشم عمران تأثير تعديل نمط الحياة على ضبط الداء السكري من النمط الثاني في سوريا. تشير الدراسة إلى أن ضبط غلوكوز الدم بشكل محكم يقلل من اختلاطات الأوعية الدموية الصغيرة والكبيرة لدى مرضى السكري. تم تقسيم 104 مرضى إلى مجموعتين: الأولى تعالج بالغليبنكلاميد فقط، والثانية تعالج بمشاركة الغليبنكلاميد مع الميتفورمين. بعد متابعة لمدة ثلاثة أشهر، أظهرت النتائج أن تعديل نمط الحياة وتثقيف المرضى لهما دور كبير في تحسين ضبط غلوكوز الدم وتحسين الحالة العامة للمرضى. تم تقييم الفعالية العلاجية باستخدام مقايسة الخضاب الغلوكوزي HbA1c واعتماد القيمة < 6.5% كقيمة هدف. أظهرت النتائج أن المعالجة المدعومة بتعديل نمط الحياة كانت أكثر فعالية من العلاج التقليدي في ضبط غلوكوز الدم وتحسين صحة المرضى بشكل عام. الدراسة تؤكد على أهمية التغذية العلاجية والنشاط البدني كجزء من إدارة مرض السكري.
Critical review
تعد هذه الدراسة خطوة مهمة في فهم تأثير تعديل نمط الحياة على ضبط الداء السكري من النمط الثاني. ومع ذلك، هناك بعض النقاط التي يمكن تحسينها. أولاً، كان من الممكن أن تكون الدراسة أكثر شمولية إذا تم تضمين مجموعة أكبر من المرضى ومن مختلف المناطق الجغرافية في سوريا. ثانياً، لم يتم تناول تأثير العوامل النفسية والاجتماعية على التزام المرضى بتعديل نمط حياتهم، وهو جانب مهم يمكن أن يؤثر على النتائج. ثالثاً، كان من الأفضل تضمين فترة متابعة أطول لتقييم الاستدامة الطويلة الأمد للتغييرات في نمط الحياة. وأخيراً، كان من الممكن توضيح المزيد من التفاصيل حول البروتوكولات الغذائية والرياضية المستخدمة لتكون الدراسة أكثر شفافية وقابلة للتكرار.
Questions related to the research
  1. ما هو الهدف الرئيسي من الدراسة؟

    الهدف الرئيسي من الدراسة هو مقارنة تأثير تعديل نمط الحياة على فعالية استراتيجيتين علاجيتين معتمدتين عالمياً لتدبير الداء السكري من النمط الثاني في سوريا.

  2. ما هي المعايير المستخدمة لتقييم الفعالية العلاجية في الدراسة؟

    تم تقييم الفعالية العلاجية باستخدام مقايسة الخضاب الغلوكوزي HbA1c واعتماد القيمة < 6.5% كقيمة هدف.

  3. ما هي النتائج الرئيسية التي توصلت إليها الدراسة؟

    أظهرت النتائج أن المعالجة المدعومة بتعديل نمط الحياة وتثقيف المرضى كانت أكثر فعالية من العلاج التقليدي في ضبط غلوكوز الدم وتحسين صحة المرضى بشكل عام.

  4. ما هي التوصيات التي قدمتها الدراسة بناءً على النتائج؟

    توصي الدراسة بأهمية تضمين تعديل نمط الحياة والتغذية العلاجية والنشاط البدني كجزء من إدارة مرض السكري لتحسين ضبط غلوكوز الدم والحالة الصحية العامة للمرضى.


References used
Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care. Jan 2003;26 Suppl 1:S5-20
Pittas A.pathophysiology of endocrinology, diabetes and metabolism. open course ware – tufts university.2005
Lebovitz H .Therapy for Diabetes Mellitus and Related Disorders. American Diabetes Association. June 2009;660-65
American Diabetes Association. Nutrition recommendations and interventions for diabetes: a position statement of the American Diabetes Association. Diabetes Care. 2008;31:S61-S78
Wing RR, Lang W, Wadden TA, Safford M, Knowler WC, Bertoni AG, et al. Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with type 2 diabetes. Diabetes Care. Jul 2011;34(7):1481-6
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