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Register a new userStudy the Hypoglycemic Effect of Ethanolic Extract of Myrtus Communis L In Diabetic Rats
دراسة أثر الخلاصة الكحولية لنبات الآس في خفض سكر الدم عند الجرذان السكرية
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Damascus University ورقة بحثية
Publication date
2013
fields
Pharmacy
and research's language is
العربية
Authors
عصام الناصر( باحث )
Created by
Shamra Editor
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دراسة تأثير الخلاصة الكحولية لأوراق الآس Myrtus communis L في سكر دم للجرذان ذات داء السكر المحدث تجريبياً.
to investigate the effect of Myrtus communis L ethanolic extract in streptozotocine-induced diabetic rats.
References used
Shikhiev AS, Abbasov RM, Mamedova ZA. Composition of Myrtus communis essential oil. Khimiya Prirodnykh Soedinenii. 1978;4:529–530
Satrani B, Farah A, Talbi M. Fractional distillation effect on the chemical composition and antimicrobial activity of Moroccan Myrtle. Acta Bot Gallica. 2006;153:235–242
Romani A, Pinelli P, Mulinacci N, Vincieri FF, Tattini M. Identification and quantification of polyphenols in leaves of Myrtus communis. Chromatographia. 1999;49:17–20
rate research
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to investigate the effect of Pelargonium odoratissimum ethanolic extract (POEE)
in alloxan-induced diabetic rats.
Single nodes and axillary buds excised from adult trees of Myrtle (Myrtus
communis L.) grown in the field under natural conditions at Damascus
countryside (Ain Elfiegh) were used as primary explants, which were surfacedisinfected
by 70% Ethanol an
d Clorox containing 5.25 % Sodium Hypoclorite
with a drop of Tween 20 for different periods and concentrations before being
placed onto MS basal medium. Established cultures were then transferred onto
MS basal medium containing a combination of growth regulators at different
concentrations (BA at 2.22 and 4.44 μM) each with NAA at 0.54, 1.62, 5.4 μM
or 1.47 μM IBA with GA3 at 0.58 μM for all tratments. Multiplication rate of
12.8-fold was achieved every 4 weeks on MS medium supplemented with 4.44
μM BA with 1.47 μM IBA and GA3 at 0.58 μM.
This research was carried out to determine the quantity of essential oil extracted
from myrtle Myrtus communis L leaves, by hydro distillation, and to identify the
major and minor components, besides to determine its quantities in the essential oil
by Gas Chromatography-Mass Spectrometry GC-MS. The samples were collected
on November 2013 from eight different climatic locations (Aleppo, Zarzour, Alzenea,
Katra AL-Rayhan, Al- Rayhana, Kasab, Mashta al-Holou and Mosiaf). The
quantity and composition of the essential oil were estimated on the basis of the
leaves dry weight. Oil quantity varied between the studied genotypes from different
locations, which range from 0.46 to 0.55 ml, with non-significant differences.
Eighteen compounds were identified in myrtle essential oil, and there were
significant differences in 13 compounds. 1,8-Cineole performed the highest rate
(18.85%) compared with other components, followed by α-Pinene (16.93%). While
the lowest percentage was (0.31%) of Myrcene. The
The specific aim of this study was to investigate the effects of
Methalonic Extract of Fenugreek and Nigella Sativa On Glucose
Levels In Blood In Diabetic Male Rabbits. The experiment was
carried out on(42) At Diabetic Male Rabbits divided into(7) groups
(6) animals of each.
A known weight of Abrus seeds powder were soaked in cِhloroformmethanol
(2:1) and extracted for 18 hours, the mixture then filtrated and reextracted
with equal volume of water and evaporated to dryness. The crude
extract is regarded as cِhloroform
-methanol extract of Abrus Seeds (crab's eye).
Chloroform-methanol extract was analyzed by HPLC and GC-MS
chromatography for identification and purification of the extract components.
Trigonelline and Abrine were isolated, a solution of a definite concentration
was made from crab's eye extract and its pure components, trigonelline and
Abrine, then oral administration of this solution of a definite concentration
were given to the Alloxan diabetic rats.
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