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Register a new userStudy the Hypoglycemic Effect of PelargoniumOdoratissimum in Diabetic Rats In Comparison With Oral Hypoglycemic Agents
تحري تأثير نبات العطرة عند الجرذان السكرية و مقارنته بخافضات السكر الفموية
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دراسة تأثير الخلاصة الكحولية لأوراق العطرة Pelargonium odoratissimum في سكر دم للجرذان ذات داء السكر المحدث تجريبياً.
to investigate the effect of Pelargonium odoratissimum ethanolic extract (POEE) in alloxan-induced diabetic rats.
References used
Bennett WL, Odelola OA, Wilson LM, Bolen S, Selvaraj S, Robinson KA, Bass EB, Puhan MA. Evaluation of guideline recommendations on oral medications for type 2 diabetes mellitus: a systematic review. Ann Intern Med. 2012; 156: 27-36
Noble D, Mathur R, Dent T, Meads C, Greenhalgh T. Risk models and scores for type 2 diabetes: systematic review. BMJ. 2011, 28;343:d7163
Norm R.C. Campbell, MD FRCPC. Hypertension in people with type 2 diabetes. Can Fam Physician. 2011; 57(9): 997–1002
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to investigate the effect of Myrtus communis L ethanolic extract in
streptozotocine-induced diabetic rats.
Glimepiride, glipizide, glyburide and repaglinide belong to two classes of oral glucose lowering agents, sulfonylureas and meglitinides, which are used to help control blood sugar levels in patients with type 2 diabetes.
The study has been done with Wister Rats have disease by 0.1 ml
Complete Freund Adjuvent in right foot. At day 14 we gave
Rosuvastatin (5- 20) mg/ kg PO and Dexamethazone 0.05 mg/kg
IM until the day 28. At day 28 the joints have been studied
hyst
ologically.
This study was conducted on twenty white rats were distributed into five
groups and injected over a month and a half at different doses (ranging
from 150 - 950 mg / kg) of cimetidine.
Introduction: Ileus commonly occurs after abdominal surgery, and is associated
with complications and increased length of hospital stay. Post-operative ileus (POI) is an
important reason for remaining patients not permit oral (NPO) in post-operativ
e period.
The tradition was that when patients passed flatus, they were ready to consume a liquid
diet, and then a solid food diet was gradually introduced. This approach was taken to avoid
aspiration, gastric and intestinal distension, and anastomotic dehiscence. Although studies
demonstrated that the conventional strict feeding regimens were not necessary, many
surgeons still hesitated to allow early oral feeding. There has been concern that early oral
intake would result in vomiting and severe paralytic ileus with subsequent aspiration
pneumonia, wound dehiscence and anastomotic leakage. This belief has become surgical
dogma, unsupported by scientific evidence. Aim: to investigates the effect of early oral
postoperative carbohydrates feeding on postoperative outcome. Material and
methods: forty abdominal surgery patients were randomly assigned to early oral
postoperative feeding group (20) or traditional feeding group (20). In the early feeding
group (study group), patients were initially started on clear fluid only 16 h after surgery
and progressed to liquids (after 24 h) and then soft and regular diet in next day (after 48 h).
In the post-operative period, the patients were visited each 12 h and clinical signs and
symptoms such as, time of passed flatus and moved their bowels, nausea and vomiting, and
the length hospital stay were assessed. Conclusions: This study showed that early oral
postoperative carbohydrates feeding group passed flatus and moved their bowels much
sooner than the control group thus reducing the duration of POI and hospital stay, but there
is no increase in occurrence of of nausea and vomiting between tow groups.
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