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Blood glucose control reduces the microvascular and macrovascular complications in patients with diabetes mellitus type II. According to the American Diabetes Association, less than a half of those with diabetes achieve optimal control of blood gluc ose and target values of HbA1c. Life style modifications is one of the preferences of diabetes management because the potential relationship between diet and diabetic control. So nutrition therapy which given by dietitian and generally lifestyle modifications are considered mainly integrated to traditional medication for disease. The study included 104 patients with diabetes type II (HbA1c 8% ± 1.07, BMI 26.45 ± 2.69, fasting blood glucose 148.25 ± 33.76) given diabetes self-management education program and divided into two groups. The first group was treated with glibenclamide only and the second was treated with a combination of glibenclamide and metformin. After three months monitoring, 103 patients Completed the study. Therapeutic efficacy was evaluated considering HbA1c ≤ 6.5% as a target value. The necessary statistical study to analyze the data and evaluate the statistical significance of the results was made. The results indicate that the treatment supported with life style modifications was more effective than traditional therapy and patient education at blood glucose control in patients with diabetes mellitus type II and improve their health.
This study was conducted in the laboratories of the Faculty of Science In the spring on 2013, after being subjected to gavage for 4 weeks through a standard diet supplemented fat by 3% to two groups (6animales per group) the experimental group beca me aqueous extract 150 mg/kg Body weight for 4weeks while the control group became standard food and tap water ad libitum. The Blood samples were collected each week, and then the serum samples were taken to the biochemical tests to determine total cholesterol, triglycerides and glucose levels in biochemistry laboratory of the Institute of Intermediate medical in Tishreen University.
In this study, we have investigated the functional relationship between blood glucose levels and induced locomotor activity both with and without the adrenal hormone Corticosterone tacking in consideration the well-known interaction with the serotonergic system.
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