The wide geographical spread and the exponential growth of the numbers of goats
around the world clearly demonstrate the ability of these ruminants to adapt to
harsh climates and grazing land. The aim of this study was to assess the genetic
divers
ity of 42 samples of Syrian goats from many domestication stations including
Jabali, Shami and hybrid (hybridization between both Shami and Jabali). The study
was done by DNA extraction of these samples, application of SSR technology using
7 microstellite markers. The alleles number of markers were 29 alleles, at a rate of
4.1 allele for each genetic locus. The number of alleles of each locus ranged from 3
alleles in genetically markers (BMS1714, INRAD07, SRCRSP09) to 8 alleles at the
genetic marker SRCRSP01. The rate of allele-frequency across all studied genetic
sites ranged from 0.071429 with the molecular size of 210 bp for the McM527
genetic site to 0.97619 with a molecular size of 55 bp for the SRCRSP09 genetic site.
Hepcidin-25 is a peptide hormone plays an important role in
regulating the systematic iron homeostasis. This paper was
conducted to study the correlations of Hepcidin with some iron
status markers and red cell indices among patients with iron
def
iciency anemia (IDA) and healthy controls in Damascus. Our
study comprised 20 IDA patients (Hb≤11 g/dl for men and
women,Tsat≤20% and ferritin <30 ng/dl) and 10 healthy non
IDA controls. Complete hemogram was performed, iron status
markers (serum iron, total iron binding capacity and ferritin)
were measured and transferrin saturation was calculated .
The aim of this research is to shed light on the simultaneous
interpretation of textual discourse markers from English into Arabic.
The research corpus consists of three political speeches by US
president Barack Obama. In his speeches, textual dis
course markers
are intentionally used and have certain functions, so some examples
are chosen to compare original English texts to their Arabic
interpreted counterparts and to show what happens to these markers
in the process of simultaneous interpretation.
The research aimed to evaluate the genetic diversity and the genetic
relationship between 16 Hordeum vulgare genotypes (variaties and new lines),
using SSR markers. 32 primer pairs were used in the analysis, five of them
amplified primers monomorp
hic alleles, while the remaining primers detected
different alleles. A total of 126 polymorphic alleles were revealed by the 27
primer pairs. The number of different alleles detected on alocus ranged from 2
to 11with a mean of 4.66 alleles per locus. The polymorphic information content
(PIC) values ranged from 0.21 to 0.88 with a mean value of 0.49, and the gene
diversity ranged from 0.23 to 0.89 with a mean value of 0.53.The dendrogram
was established using SSR data clustered into three major groups. The smallest
genetic relationship was observed between line39 and line38 . The results proved
the efficiency of SSR markers in the estimation of genetic diversity and in the
clustering of the barley genotypes in Syria.
Several appearances were assigned in duodenum during endoscopy in patients with celiac disease, this study was conducted to determine the diagnostic value of some endoscopic markers in celiac patients in order to be used in the clinical diagnosis of
the disease an additional factor supporting the diagnosis. The study included 504 children reviewed the different symptoms (failure to thrive, chronic diarrhea or constipation, unexplained anemia, weight loss), and underwent an upper gastrointestinal endoscopy. Four markers were evaluated in the second and third part of the duodenum are: scalloping, reduction of duodenal folds, nodular mucosal pattern, and chronic inflammation (punctate whitish spots) . Celiac disease was diagnosed at 123 patients, which was based on the result of the pathology biopsy taken during endoscopy, the patients ranged in age from 6 months to 15 years. Scalloping was the highest sensitivity and specificity marker of 89% ,96 % respectively. Diagnostic values for these signs in general ( 91% sensitivity, 76% specific, positive predictive value 56 %, and negative predictive value 97% ). We observed that the presence of celiac disease, as well as histological grade rating by Marsh classification respect to the existence of endoscopic markers.
The objective of this study was to characterize and determine the genetic
variation among twelve cultivars and four rootstocks, belonging to Amygdalus
genus in Syria using the simple sequence repeats (SSRs) marker. It was found
that 154 alleles we
re identified by using 26 primer pairs, and the proportion of
the specific ones was 30.52%. In addition, it was revealed that all the studied
SSR loci produced polymorphic alleles. The average of PIC, He and Ho were
0.58, 0.61, 0.31, respectively.
Samples of Capparis spinosa plant were collected from 6 sites in Aleppo and Lattakia
provinces. The genetic variations were studied using the AFLP technique in order to determine the
genotypes of the studied types using 3 primers, which showed ampl
ification. Statistical analyses
were conducted using the dissimilarity coefficient and genetic diversity coefficient. The A.C.P. and
the statistical -F were calculated, and the similarity dendrogram was constructed. The results
showed the following:
The presence of a certain number of specific alleles (descriminates) for each province.
The presence of genetic and reproductive isolation deterrent to gene flow between the two
provinces.
The heterozygoty average was a little higher in Lattakia (0.486) than in Aleppo (0.481). The
mean of genetic diversity coefficient of primers and individuals was a little higher in Aleppo
(0.677) than in Lattakia (0.653). The population mean was very close: (0.759) in Aleppo and
(0.760) in Lattakia. This may be explained on the basis of silent and specific alleles due to deletion
mutations, different selective effects as well as the reproduction system in the two cities.
The greatest genetic distance in Aleppo was (0.381) noted between (Al Dahea and Al Shekh
saaed), and in Lattakia (0.38) noted between (Al Amroniah and Jabla). However, the greatest
genetic similarity in Aleppo was (0.637) noted between (Al Shekh Saaed and Turkman Bareh), and
in Lattakia (0.675) noted between (Wata Deirzenon and Jabla). The variation between these values
was graduated.
The study of statistical –F showed the effect of the similarity factor in some populations.
This was more significant in Aleppo than in Lattakia, which indicates that the reproduction system
is more closed in Aleppo, and this refers as well to inbreeding or self pollination which showed
high genetic variations in these populations when compared with Lattakia.
The results of this study helped in determining primers that can be used as molecular
markers in a breeding program for Capparis spinosa as a medicinal plant. This technique showed
high efficiency in studying the similarity relationships between these two cities.
Cancer stem cells in solid tumors are a "rare" group of cells and
their role in carcinogenesis has been proven during the past few
years. The pursuit for specific oral epithelial stem cell surface
markers leads to the identification of markers su
ch as CD44
and Bmi-1. The combination between CD44 which has been
considered a potential prognostic marker for cancer stem cells in
Head and Neck Squamous Cell Carcinoma (HNSCC), and Bmi-1
the pluripotency stemness marker may lead to identify the cells
sharing the properties of both markers and could give a closer look
into its appearance and density in the tissue. The aim of this study
was to study the percent of cells stained positive for both markers
and the histological grade of (HNSCC) and the anatomic location
of the tumor. Statistical analysis showed that higher density of
positive stained cells for both markers was in the severe grade of
the tumor, whereas the second higher ratio was in the mild grade
then the moderate , there was no significant association between the density of cells and the anatomical location. Our results suggest that the two markers together could be used as prognostic factors for patients with even mild grade SCC, which might help in prediction of recurrence.
Ephedra is a dioecious, drought- and frost-resistant, perennial, evergreen shrub
with high medicinal value due to its content of ephedrine alkaloids. It became quite clear throughout
referential studies that this significant medical plant which is spontaneously widespread in Syria and there
have been an increased international demand on it hasn’t been studied yet.
Recent studies has focused on the impact of periodontal disease on the general
health like cardiovascular disease and hypertension and their interactions. We aimed to study several
vascular thrombotic markers levels in patients with chronic periodo
ntitis and hypertension.
Periodontitis in hypertensives was associated with an elevation in platelets count and
fibrinogen concomitantly with an increase in blood glucose levels and body mass index,in addition to
greater pocket probing depth and clinical attachment loss, compared with periodontitis only.These results
shed the light on periodontitis as a risk indicator for hypertension and thrombotic propensity in
susceptible individuals.
