Effects of age, sex and genetic factors on chronic periodontitis severity in Syrian Patients

Chronic periodontitis (CP) is an inflammatory disease, characterized by gingivitis, and affecting tooth supporting tissues, forming periodontal pockets with associated attachment loss, alveolar bone resorption. It is common in adults, but can also occur at any age. The rate of disease progression may be influenced by local, systemic conditions, and/or environmental factors that alter the normal host response to bacterial plaque, and affect the susceptibility to disease.It is suggested that periodontitis is partially associated by genetic factors, that many genes are involved in inflammation susceptibility, mainly include the vitamin D receptor (VDR) gene that is implicated in bone metabolism and the host immune response. 80 Syrian subjects were recruited for vitamin D receptor gene polymorphism study, and allocated in two groups: 50 diagnosed with CP and mean age was (64 ± 0.722) years, 30 matched controls. DNA was isolated from peripheral blood cells, and genotyping was performed by polymerase chain reaction (PCR) method and restriction fragment length polymorphism analysis (RFLP) by using FokI enzyme. By using Chi square test, no significant differences were found between the study groups in the frequencies of alleles and genotypes at FokI position of VDR gene, age and sex. These findings suggest that the investigated factors are not associated with periodontal disease in this studied sample of Syrian population.

A clinical study to evaluate the effect of hyaluronic acid on periodontal infra-bony pockets during four months

Esterified hyaluronic acid has emerged into the periodontal regenerative therapy recently, but there is still a need for more research of its role in periodontal treatments, therefore the goal of this clinical study is to assess its role in the treatment of periodontal infrabony defects in comparison to open curettage.

A Comparative Clinical And Laboratory Study Of Diabetic And Non-Diabetic Chronic Periodontitis Patient In The Eastern District Of Hama

This study aimed to evaluate the clinical and microbiological effect of fluoride in drinking water on the severity of chronic periodontitis and its effect on the relationship between diabetes and periodontitis.

Treatment of Class II Furcation Defects Using Bovine-Derived Xenograft (BDX) With or Without Platelet-Rich Plasma (PRP)

The study aimed to Compare the effect of combination Platelet Rich Plasma with bovine derived xenograft and bovine derived xenograft alone in treatment of human class II furcation defects in mandibular molars. Twenty systemically healthy patients, aged 32 to 58 years with chronic periodontitis participated in the study . Each patient had 2 buccal mandibular class II furcation defects (first or second molars) were randomizely treated either with : bovine – derived xenograft with Platelet – Rich plasma, or with bovine - derived xenograft alone.

A Comparison Of The Efficiency Of Er:YAG Laser To Ultrasonic scaling In Chronic Periodontitis Treatment

The aim of the study is comparison of the efficiency of Er:YAG Laser with Ultrasonic scaling in Chronic Periodontitis Treatment.

Role of Interleukin 1 Genes in Atherosclerosis and Chronic Periodontitis in Syrian Population

The role of Interleukin-1 genes in the association between chronic periodontitis and atherosclerosis has been under debate. The purpose of this study is to compare the existence of interleukin1 genes polymorphism in the chronic periodontitis subjects with and without atherosclerosis.

Evaluating Thrombotic Markes in Chronic Periodontitis with Hypertension

Chronic Periodontitis is accompanied with subacute systemic inflammatory responses and a procoagulant state which manifests in changes of some serological vascular thrombotic markers levels. This study aimed to evaluate several vascular thrombotic markers levels in patients with chronic periodontitis.

Studying Thrombotic Markes in Chronic Periodontitis with Hypertension

Recent studies has focused on the impact of periodontal disease on the general health like cardiovascular disease and hypertension and their interactions. We aimed to study several vascular thrombotic markers levels in patients with chronic periodontitis and hypertension. Periodontitis in hypertensives was associated with an elevation in platelets count and fibrinogen concomitantly with an increase in blood glucose levels and body mass index,in addition to greater pocket probing depth and clinical attachment loss, compared with periodontitis only.These results shed the light on periodontitis as a risk indicator for hypertension and thrombotic propensity in susceptible individuals.

A Comparative of the Efficiency of Er:YAG Laser to Scaling and Root Planing in Chronic Periodontitis Treatment

Many methods are used to treat Periodontitis such as scaling and root planing (SRP) with hand instruments, Sonic and Ultrasonic instruments. Recently, lasers are used in periodontal. The aim of the study is to compare the Efficiency of Er:YAG Laser Combined with Scaling and Root Planing in Chronic Periodontitis Treatment.

Clinical Follow-Up of Aggressive Periodontitis after Comprehensive Periodontal Therapy Supported by Systematic Metronidazol and Amoxicillin

The outcomes of aggressive peiodontitis therapy (AgP) are not always successful. The aim of the study is to assess the improvement of periodontal status of AgP after surgical periodontal therapy supported by systemic dosages of metronidazol and amoxicillin.