Several appearances were assigned in duodenum during endoscopy in patients with celiac disease, this study was conducted to determine the diagnostic value of some endoscopic markers in celiac patients in order to be used in the clinical diagnosis of
the disease an additional factor supporting the diagnosis. The study included 504 children reviewed the different symptoms (failure to thrive, chronic diarrhea or constipation, unexplained anemia, weight loss), and underwent an upper gastrointestinal endoscopy. Four markers were evaluated in the second and third part of the duodenum are: scalloping, reduction of duodenal folds, nodular mucosal pattern, and chronic inflammation (punctate whitish spots) . Celiac disease was diagnosed at 123 patients, which was based on the result of the pathology biopsy taken during endoscopy, the patients ranged in age from 6 months to 15 years. Scalloping was the highest sensitivity and specificity marker of 89% ,96 % respectively. Diagnostic values for these signs in general ( 91% sensitivity, 76% specific, positive predictive value 56 %, and negative predictive value 97% ). We observed that the presence of celiac disease, as well as histological grade rating by Marsh classification respect to the existence of endoscopic markers.
