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Background: people with cancer experience great changes in their life as a result of disease, treatment and disease prognosis which affect their quality of life .with the goal of investigating breast cancer patient's quality of life during chemother apy in Tishreen hospital in Latakia.. Methods: 60 patients were invited to complete the European organization of research and treatment quality of life questionnaire version 3 and breast cancer quality of life module during their early stage of chemotherapy. Results : the results show that the (73.3%) were under the age of fifty and half of them reported total health status score under (50) which reflects low quality of life in addition to impaired psychological ,social, cognitive and role functioning. Also more than 67% of patient suffered from chemotherapy- related side effects as nausea and vomiting, dyspnea, loss of appetite, insomnia, and fatigue. In addition to variance in quality of life scores according to age, marital status, occupation and level of education without changing of it by educational level. In addition to that the majority of patient had impaired sexual function and upset of hair loss and arm symptoms but with positive and optimistic future. perspective. No significant differences in quality of life scores were found between urban and rural patients. Conclusion. Health care provider should assess routinely cancer patient quality of life during treatment to ascertain of providing appropriate care with supportive services for all patients
Background: A cancer patient demands information, not only to assist him to understand the disease and its treatment, but also to allow him to interpret the negative events and action taken, through the course of disease, so that the threat inherent from the diagnosis and treatment becomes lessened. Methods: With the goal of studying the information needs and source of information of women with breast cancer who were receiving chemotherapy, 60 patients were invited to complete a self-administered questionnaire which consists of 47 item about information needs and 3 questions about sources of information with three choices (personnel, printed materials and mass media). They fill it at the early stage of their chemotherapy treatment. Results :The results showed that the majority of patients reported high level of information needs. Cancer and its spread, treatment, and side effects of chemotherapy as well as its management were priority information needs, in addition to the possibility of cancer occurrence among sisters and daughters. Results also demonstrated that the patients depended on doctors and other patients as sources of information more than on nurses and the internet. Conclusion: Findings indicate that there is a need for the provision of education program that addresses patients' information needs. Moreover, there is a necessity for ascertaining the role of educational nursing in affording holistic nursing care for breast cancer patien
A retrospective study included 25 cases with inflammatory breast cancer. The patients were admitted to AL-Assad University Hospital, Lattakia, Syria (average age 55, and range 49-61 years old). The most common clinical signs and symptoms were: erythe ma 100%, edema 100%, enlarged axillary nodes 100%, Nipple flattened/inverted 96%, warm Breast 92%, Ridges/thickening of breast 84%, Peau d’orange 88%, painful/tender Breast 88%, and Mass 80%. Mammography findings were: an increase in skin thickness 100%, an increased tissue density in the involved breast 100%, and an asymmetric widening of the sub-cutaneous lymphatic vessels 33.33%. 80% of cases were diagnosed as stage IV. All patients received primary neoadjuvant chemotherapy for three cycles. After that a modified radical breast mastectomy and axillary lymph nodes dissection were performed for all patients. The wound edges were closed primarily after dissecting the skin in 76%, for 4 patients 16% a split-thickness skin grafts were performed, and for 2 patients 8% a Latissimus dorsi pedicled myocutaneous flap was performed.
Breast cancer is the second leading cause of death of women in the world. The early detection gives a better chance to cure it. Physicians diagnose breast tumors by analyzing the characteristics of the lesion in ultrasound images. Shape data, provi ded by a tumor contour, is important to physicians in making diagnostic decisions. However, due to the increasing use of technology in medicine, a computer aided detection systems (CAD) have been built to help the expert. This research focuses on using a level-set method as an effective lesion segmentation method for breast ultrasound images. By applying non-local means filter on image, the unwanted speckle noise will be removed and the image's important details will be preserved. Then the initial contours are sketched using the GUI in order to apply level-set method which delineates the contour of the lesion in breast ultrasound image. The proposed method was found to determine the breast tumor contours that are very similar to manual-sketched contours (about 96%).
Background& Objective: Determining the risk of distant metastasis in invasive breast cancer patients with lesions measuring 40 mm or less, and comparing the risk between quadrantectomy with axillary dissection and modified radical mastectomy with a xillary dissection. Materials & Methods: The study was performed prospectively by evaluating a random sample of invasive breast cancer patients with lesions measuring 40 mm or less, who presented to Al-Byroni University Hospital in Damascus during one year between 9/8/2009 and 9/8/2010. Results: Ninety-four breast cancer patients were evaluated. The median age of patients was 54 years. Excisional biopsy was the most common diagnostic tool (41%), and frozen section was used in 27% of patients. The tumor was located in the upper lateral quadrant in 65% of patients. The tumor was in stage one in only 13% of cases, and most tumors were in stage II (63%). Modified radical mastectomy with axillary dissection was performed in 62 patients (66%), and quadrantectomy with axillary dissection was performed in 32 patients (34%). The patients were followed for up to 18 months. Distant metastasis were observed in 8 patients (13%) from the first group and 6 patients (19%) of the second group. Conclusion: There is no important difference of risk of distant metastasis after modified radical mastectomy or quadrantectomy in breast cancer lesions measuring 40 mm or less. We recommend quadrantectomy as the first-line surgical treatment for breast cancer when indicated.
The aime of this study is to assess the effect of a multimodal group exercise intervention, as an adjunct to conventional care, on fatigue, physical capacity, general wellbeing, physical activity, and quality of life in patients with breast cancer wh o were undergoing adjuvant chemotherapy. The study was conducted in Tishreen university hospital in Lattakia the participants were 164 women with breast cancer. Supervised exercise comprising high intensity cardiovascular and resistance training, relaxation and body awareness training, massage, nine hours weekly for six weeks in addition to conventional care, compared with conventional care. The intervention group showed an estimated improvement at six weeks for the primary outcome, fatigue, of −6.8 (−12.3 to −0.9), P=0.02. Significant effects were seen on vitality for physical functioning 2,5 (-0,4 to 5,2), role physical 4,5 (-1,8 to 11,1), role emotional -0,3 (-4,0 to 3,3), and mental health 1,9 (-2,5 to 6,1) scores. No significant effect was seen on global health status/quality of life. A supervised multi modal exercise intervention including high and low intensity components was feasible and could safely be used in patients with breast cancer who were receiving adjuvant chemotherapy or treatment for advanced disease. The intervention reduced fatigue and improved vitality, muscular strength, and physical and functional activity, and emotional wellbeing, but not quality of life.
112 patients with suspected breast lesions were investigated using Scintimammography with 99mTc-MIBI, mammography and magnetic resonance to compare the diagnostic accuracy of Scintimammography with that of mammography and magnetic resonance in the d etecting of primary breast cancer. Excisional biopsy was taken after 7-10 days of Scintimammography. 70 patients were diagnosed with breast cancer; 55 palpable and 15 non-palpable lesions, while 42, 30 palpable and 12 non-palpable were diagnosed as benign lesions. The sensitivity of the three methods were high and approximate (89% by Scintimammography, 90% by mammography and 94% by magnetic resonance), while Scintimammography showed higher specificity (86%) versus 21% for mammography and 50% for magnetic resonance. The high specificity in addition to high positive (91%) and negative (82%) predictive values of Scintimammography resulted in a highly accurate diagnostic (87%) method compared to mammography (64%) and magnetic resonance (78%) procedures. Through the complementary use of Scintimammography it is possible to increase the sensitivity for the detection of breast cancer. In patients in whom the status of a palpable breast mass remains unclear, Scintimammography may help to reduce the amount of unnecessary biopsies.
In spite of all the advances in health care and medical technology, provision of quality health care to cancer patients remains one of the major challenges that health care professionals have to face in the next years. this study was conducted to assess the effect of nursing care on breast cancer patients quality of life at homes. by using quazi-experimental design 80 breast cancer patients were selected (40 experimental group ,40 control group) receiving chemotherapy recently. Experimental group patients received supportive psycho-educational interventions consisted of education, progressive muscle relaxation technique with four supportive range of motion exercises in addition to emotional support for three months. While control group patients received routine nursing care in hospital. The results were assessed for both groups by using European organization for cancer research and treatment quality of life questionnaire (EOCRT-QLQ C30) and breast cancer module.
Breast cancer is the most widespread types of cancer among women. An efficient diagnosis in its early stage can give women a better chance of full recovery. Calcification is the important sign for early breast cancer detection. Mammography is the m ost effective method for breast cancer early detection using low radiation doses. The studies improved the sensitivity of mammogram from 15% to 30% based on Computer Auto-Detection CAD systems, which are used as a “second opinion” to alert the radiologist to structures that, otherwise, might be overlooked. This article summarizes the various methods adopted for micro-calcification cluster detection and compares their performance. Moreover, reasons for the adoption of a common public image database as a test bench for CAD systems, motivations for further CAD tool improvements, and the effectiveness of various CAD systems in a clinical environment are given.
Assessment of quality of life after surgical treatment in breast surgery patients, and comparing quality of life between quadrantectomy and modified radical mastectomy for invasive ductal carcinoma measuring 40 mm or less.
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