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Register a new userComparison of Quality of Life after Quadrantectomy and Modified Radical Mastectomy in Breast Cancer Measuring 40 mm or Less
دراسة مقارنة لنوعية الحياة بعد استئصال الثدي الربعي و استئصال الثدي الجذري المعدل في سرطانات الثدي القنوية الغازية ذات القطر 40 ملم أو أقل
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تقييم تأثير المعالجة الجراحية المتبعة في سرطان الثدي في نوعية الحياة، و مقارنة نوعية الحياة بين المريضات اللواتي خضعن لاستئصال الثدي الربعي، و اللواتي خضعن لاستئصال الثدي الجذري المعدل في سرطانات الثدي القنوية الغازية ذات القطر 40 ملم أو أقل.
Assessment of quality of life after surgical treatment in breast surgery patients, and comparing quality of life between quadrantectomy and modified radical mastectomy for invasive ductal carcinoma measuring 40 mm or less.
References used
Althuis MD, Dozier JM, Anderson WF, et al. Global trends in breast cancer incidence and mortality 1973– 1997. Int J Epidemiol. 2005;34(2):405–412
Jatoi I, Proschan MA. Randomized trials of breast-conserving therapy versus mastectomy for primary breast cancer: a pooled analysis of updated results. Am J Clin Oncol. 2005;28(3):289–294
Pandey M, Thomas BC, SreeRekha P, et al. Quality of life determinants in women with breast cancer undergoing treatments with curative intent. World J Surg Oncol. 2005;3:63
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Background& Objective: Determining the risk of distant metastasis in invasive breast cancer patients
with lesions measuring 40 mm or less, and comparing the risk between quadrantectomy with axillary
dissection and modified radical mastectomy with a
xillary dissection.
Materials & Methods: The study was performed prospectively by evaluating a random sample of invasive
breast cancer patients with lesions measuring 40 mm or less, who presented to Al-Byroni University
Hospital in Damascus during one year between 9/8/2009 and 9/8/2010.
Results: Ninety-four breast cancer patients were evaluated. The median age of patients was 54 years.
Excisional biopsy was the most common diagnostic tool (41%), and frozen section was used in 27% of
patients. The tumor was located in the upper lateral quadrant in 65% of patients. The tumor was in stage
one in only 13% of cases, and most tumors were in stage II (63%). Modified radical mastectomy with
axillary dissection was performed in 62 patients (66%), and quadrantectomy with axillary dissection was
performed in 32 patients (34%). The patients were followed for up to 18 months. Distant metastasis were
observed in 8 patients (13%) from the first group and 6 patients (19%) of the second group.
Conclusion: There is no important difference of risk of distant metastasis after modified radical
mastectomy or quadrantectomy in breast cancer lesions measuring 40 mm or less. We recommend
quadrantectomy as the first-line surgical treatment for breast cancer when indicated.
Background: people with cancer experience great changes in their life as a result of disease, treatment and disease prognosis which affect their quality of life .with the goal of investigating breast cancer patient's quality of life during chemother
apy in Tishreen hospital in Latakia..
Methods: 60 patients were invited to complete the European organization of research and treatment quality of life questionnaire version 3 and breast cancer quality of life module during their early stage of chemotherapy.
Results : the results show that the (73.3%) were under the age of fifty and half of them reported total health status score under (50) which reflects low quality of life in addition to impaired psychological ,social, cognitive and role functioning. Also more than 67% of patient suffered from chemotherapy- related side effects as nausea and vomiting, dyspnea, loss of appetite, insomnia, and fatigue. In addition to variance in quality of life scores according to age, marital status, occupation and level of education without changing of it by educational level. In addition to that the majority of patient had impaired sexual function and upset of hair loss and arm symptoms but with positive and optimistic future.
perspective. No significant differences in quality of life scores were found between urban and rural patients. Conclusion. Health care provider should assess routinely cancer patient quality of life during treatment to ascertain of providing appropriate care with supportive services for all patients
recurrence is a major problem which affects 40% of Breast cancer patients . Bcl2 is an antiapoptotic protein which is implicated in many cases of cancer development and cancer resistance to therapy.
Aim of study : investigate the role of Bcl2 in recurrence in Breast cancer patients
In spite of all the advances in health care and medical technology,
provision of quality health care to cancer patients remains one of the
major challenges that health care professionals have to face in the
next years.
this study was conducted to
assess the effect of nursing care on
breast cancer patients quality of life at homes.
by using quazi-experimental design 80 breast cancer patients were
selected (40 experimental group ,40 control group) receiving
chemotherapy recently. Experimental group patients received
supportive psycho-educational interventions consisted of education,
progressive muscle relaxation technique with four supportive range
of motion exercises in addition to emotional support for three
months. While control group patients received routine nursing care
in hospital. The results were assessed for both groups by using
European organization for cancer research and treatment quality of
life questionnaire (EOCRT-QLQ C30) and breast cancer module.
A retrospective study included 25 cases with inflammatory breast cancer. The patients were admitted to AL-Assad University Hospital, Lattakia, Syria (average age 55, and range 49-61 years old). The most common clinical signs and symptoms were: erythe
ma 100%, edema 100%, enlarged axillary nodes 100%, Nipple flattened/inverted 96%, warm Breast 92%, Ridges/thickening of breast 84%, Peau d’orange 88%, painful/tender Breast 88%, and Mass 80%. Mammography findings were: an increase in skin thickness 100%, an increased tissue density in the involved breast 100%, and an asymmetric widening of the sub-cutaneous lymphatic vessels 33.33%. 80% of cases were diagnosed as stage IV. All patients received primary neoadjuvant chemotherapy for three cycles. After that a modified radical breast mastectomy and axillary lymph nodes dissection were performed for all patients. The wound edges were closed primarily after dissecting the skin in 76%, for 4 patients 16% a split-thickness skin grafts were performed, and for 2 patients 8% a Latissimus dorsi pedicled myocutaneous flap was performed.
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