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Register a new userPrevalence of EBV in lymphoma Patients and its relationship with histopathological type at Oncology Unit – Tishreen University Hospital
دراسة معدل الإصابة بفيروس ابيشتاين بار EBV عند مرضى اللمفومات و علاقته بالنمط النسيجي في مركز معالجة الأورام في مشفى تشرين الجامعي
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Tishreen University ورقة بحثية
Publication date
2018
fields
Medicine
and research's language is
العربية
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Shamra Editor
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فيروس إبشتاين-بار(EBV) هو فيروس من عائلة فيروسات الهربس (الحلأ) , من أكثر الفيروسات التي تصيب البشر و يشتهر بتسببه بكثرة وحيدات النوى الخمجية, و يتهم بإحداثه عدد من الإمراضيات من بينها اللمفوما و التي تعد إحدى الآفات الخبيثة التي تحدث على حساب الخلايا اللمفاوية البائية أو التائية. و تقسم اللمفومات بشكل عام إلى: 1- لمفوما هودجكن Hodgkin 's Lymphoma 2- لمفوما لا هودجكن Non - Hodgkin 's Lymphoma أجریت ھذه الدراسة بین عامي 2016 - 2017 , في مشفى تشرين الجامعي - قسم الطب النووي , حيث بعد أن تم تشخيص اللمفوما سريريا و بالتشريح المرضي لكل مريض (أخذنا عينة دم و اجراء اختبار ELISA لتحري أضداد المستضد النووي من النوع IgG )(2) شملت الدراسة 57 مريضا منهم 31 ذكر( 54.4%) و 26 أنثى (45.6(% لم توجد أهمية إحصائية للإصابة باللمفوما حسب الجنس (P= 0.7) , كانت أعلى نسبة إصابة بين عمري 25-50 سنة كان عدد مرضى لمفوما هودجكن 26مريض 45.6% ولاهودجكن 31مريض 54.4% إن الإصابة بفيروس EBV تؤهب للإصابة باللمفومات P=0.004)), كما أن الإصابة ب EBV لاترجح للإصابة بنوع معين من اللمفوما (هودجكن-لاهودجكن) حيث (P=0.6) لاحظنا وجود علاقة بين نوع لمفوما هودجكن والإصابة بفيروس EBV حيث ((P=0.034 حيث الإصابة ترجح نوع Nodular sclerosis و Mixed cellularity Type
EBV virus is a herpes virus which affects human and causes Mononucleosis Infection and may play a role in lymphoma. lymphoma has two types (H or NH) This study was performed between 2016-2017 at Tishreen University Hospital – Oncology department; we took blood samples and performed ELISA Test (Anti EBNA IgG) to all patients with lymphoma. 57 patients (31 male 54.4% and 26 female 45.6%) with lymphoma. Sex doesn't has statistical significance on lymphoma 25-50 year was the most age group affected by lymphoma We have 26 patients with Hodgkin lymphoma 45.6% and 31 patient with nonHodgkin lymphoma 54.4% In our study EBV disease found to have a role in causing lymphoma (P=0.004) but it doesn't cause a specific type of lymphoma (P=0.06). We noticed a relationship between the type of Hodgkin lymphoma and EBV disease (P=0.034) especially Nodular sclerosis and Mixed cellularity type but we didn't notice this relationship in nonhodgkin lymphoma.
References used
MUHAMMAD AZHAR, HAFEEZ UD DIN, IQBAL MUHAMMAD, SHOAIB NAIYAR HASHMI, FARHAN AKHTAR. Frequency Of Epstein-Barr Virus In Classical Hodgkin Lymphoma. Azhar. VOL 28, NO 2 (2016)<<PUBMED
JOHN S. GREENSPAN, B.D.S., PH.D., DEBORAH GREENSPAN, B.D.S., EVELYNE T. LENNETTE, PH.D., etc. Replication of Epstein–Barr Virus within the Epithelial Cells of Oral Hairy Leukoplakia, an AIDS-Associated Lesion. N Engl J Med 1985; 313:1564-1571December 19, 1985
ALAA FADHIL ALWAN1, NIDAL KARIM AL- RAHAL2, ZEYAD AHMED SHABEEB3 . Incidence of Epstein Barr Virus infection in newly diagnosed non-Hodgkin lymphoma in the national center of hematology-single center study. Iraqi Journal of Cancer and Medical Genetics Volume 7 - Number 1 – 2014 , 21
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يقوم هذا البحث باجراء دراسة وبائية للأنماطو تحت الأنماط النسيجية للمفومالاهودجكن المشاهدة في مشفى مركزي تعليمي هو مشفى المواساة و ذلك في العقد اللمفاوية و في الأعضاء خارج العقد اللمفاوية بشكل بدئي أو توضعات ثانوية و معرفة نسبها و توزعها في كل الأعمار
و القاء الضوء على أهمية و دور التلوينات المناعية النسيجية الكيميائية في وضع تشخيص نهائي و ذلك وفقا لتصنيف عام 2008.
introduction: Diabetes mellitus is a global epidemic and a leading cause for
increasing mortality and morbidity. Although prevention and care policies exist, diabetes
continues to be a global public health problem with serious consequences. Aim: To
assess
the educational needs on diabetes among patients, level of knowledge and patient specific
characteristics that are associated with this knowledge. Method: A descriptive study was
conducted among 50 patients who entered Tishreen university between May 2017 and
December 2017. Questionnaire on different domains of diabetes such as general
knowledge, complications, treatment, life style, symptoms and prevention. Each statement
was given a score of one if it was answered correctly and zero for a wrong answer. Out of a
total score, a score of seventy percent and above was considered good knowledge ,
between thirty percent and seventy considered moderate, less than thirty considered poor
knowledge . Results: more than half, were > 50 years (54%), (54%) were males, 46% were
female. Most of educational needs were: regarding of insulin, its kinds, sides effects,
methods of prevention of diabetic foot and care it. The level of knowledge of diabetes was
moderate 63%.
Recommendation: Awareness regarding all the aspects of diabetes mellitus needs to
be increased for better control of the disease and its complications. Future studies about
effect of education program on improvement of knowledge and self care, especially about
the diabetic foot.
Chemotherapy drugs cannot tell the difference between of normal cells and cancer
cells. This means normal cells are damaged and this results in side effects, This damage
does not stop in the patient who receiving treatment but also extends to all e
mployees in
the health care sitting. Nurses are the main groups that are exposed to these drugs in
hospital setting Generally, the occupational activities that pose to greatest risk of exposure
are the preparation ,Transporting cytotoxic drugs, administration of antineoplastic agents,
cleaning of chemotherapy spills, and handling of waste. Nurses require specialized
knowledge and skills in order to ensure safety for both patients life and for their own safety
of the jobs. Because of available a lot of chemotherapy guidelines we Must assess
knowledge and skills nursing staff and assess the extent of their commitment to these
guidelines.
Objective: The objectives of this study were to assessment of knowledge and skill
of oncology nurses in chemotherapy administration.
The purpose of the study was to assess the role of the head nurses in managing the performance of the nursing staff at Tishreen University Hospital from the point of view of the nursing staff and the head nurses. The sample that have been used was av
ailable of the head nurses and the simple randomness of the nursing staff and was composed of 55.5% of head nurses and their number was (30) head nurses And 50% of the nursing staff participating in the Tishreen University Hospital during the application of the research and their number was (300) nurse. An improved tool for gathering information was used based on recent research literatures, and data were collected and analyzed using SPSS version 20. The most important results: The assessment of the role of head nurses in managing staff performance at Tishreen University Hospital in general was in a good level.
Torsion of the spermatic cord (torsion of the testis) is an important surgical
urologic emergency most commonly seen in adolescent males. It causes
strangulation of the blood supply to the testis. Unless treatment is done in
accurate time testicul
ar ischemia, functional disorders, atrophy even death
of the testis may occur. So it is an important and risky lesion necessitates
suitable management. 22 cases of testicular torsion were studied at
ALASSAD University Hospital (University of Tishreen ) during 3 years and
3 months .Diagnostic was confirmed by symptoms and clinical examination:
Acute and sudden testicular pain happened in all cases (100%), testicular
swelling was found in (95%), retracted testis with horizontal orientation in
(100%), anterior epididymal position in (100%). Colored Doppler
sonography was done in (90.9%). Surgical detorsion with contra- lateral
orchiopexy was achieved in all cases without orchiectomy.
In conclusion, testicular torsion is supposed to be suspected in all cases of
testicular, acute, sudden pain, in adolescent male and this can be verified by
complementary exameninatios as: color Doppler sonography and scintillation scan without washing time, and all cases should to be followed
up in the future.
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