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Worldwide, iron deficiency anemia (IDA) is the most common nutritional deficiency, and its management remains a challenge in many cases.(OIT)Oral iron therapy, in appropriate doses and for a sufficient duration, is an effective first-line strategy for most patients. But some patients do not experiencean optimal response to(OIT).The need is still current and clinically relevant for predictors of response to OIT. Hepcidin-25, a major regulator of iron metabolism, may be use as a reliable guide for the use of iron and be one of them.112 patientswith IDA were enrolled in this follow up clinical trial, Selected from two university, hospitals in Damascus between JUNE2015 and JUNE2016. For patients who met the inclusion criteria, Baseline CBC, iron studies, and serum hepcidin-25 were measured, and then they received a 14-day course of oral iron (ferrous gluconate 325mg/ 3 times daily). Patients who achieved <1g/dl increase in Hb in 14 days were categorized as “nonresponders”. Screening hepcidin levels were (40.18± 86.35) versus (6.37±10.37)(p= 0.041(innonresponders versus responders to oral iron trial. HepcidinCutoff of >14.3 ng/ml, showed sensitivity of 40%,specificity of 90.2%, andpositive predictive value of 60% andnegative predictive value of 80% for predicting nonresponsiveness to oral iron.We conclude that serum hepcidin25predicts poorly nonresponsivenesstooral iron therapy in IDA patients, but it is superior to ferritin and TSAT for this purpose.
Hepcidin-25 is a peptide hormone plays an important role in regulating the systematic iron homeostasis. This paper was conducted to study the correlations of Hepcidin with some iron status markers and red cell indices among patients with iron def iciency anemia (IDA) and healthy controls in Damascus. Our study comprised 20 IDA patients (Hb≤11 g/dl for men and women,Tsat≤20% and ferritin <30 ng/dl) and 10 healthy non IDA controls. Complete hemogram was performed, iron status markers (serum iron, total iron binding capacity and ferritin) were measured and transferrin saturation was calculated .
This study aimed to evaluate the effect of associating the application of Erbium-YAG laser with rapid palatal expansion in adult patients. Twenty four subjects aged between 13 - 21 years were randomly assigned to either laser group (n=12) and cont rol - traditional treatment with RPE- group (n=12). Laser group patients were undergone mucosal-bony perforations along midpalatal suture for three interventions (one a month) by Erbium-YAG laser, and two bands hyrax expander were cemented for all patients of groups. Impressions were taken for all patients and dental changes post activation and retention phases were collected and compared for both groups.
The current study aimed to examine the effects of the modified tandem appliance on the dimensions of the airways. Pretreatment and post-treatment cephalograms of twelve patients with maxillary deficiency, (7 girls, 5 boys; mean age 8±0.5 years), w ho were seeking treatment at the Department of Orthodontics, Damascus University, were studied. These patients were treated using the modified tandem appliance with rapid maxillary expansion.
Solar and wind energy is considered as one of the best renewable energy resources because it Available and economical . We can take advantage of these two resources of renewable energy in Katina area in Homs for designing and building a bilateral r esources (solar-wind) electric power system, depending on the daily bending of the wind speed and the solar radiation intensity in the studied area. This research studies the design of a hybrid wind and solar system by selecting its components that available in the local market in terms of their nominal, technical specifications, based on the technical and economic studies and the corresponding international standards. The obtained results showed that we have approximately (1246.7 Kw/Year) surplus during the year for the benefit of consumers, which makes the system economically feasible for investment, as explained in research needs an additional resource to feed the load and charge the energy-savings with (3360.2 w/day) that constituting (50.4 %) of the volume of the load in addition to the practical results provides a theoretical database, whether for the researcher or the investor in the field of renewable energies, particularly in terms of the efficiency of selecting the system’s components.
Background& Objective: Selective IgA deficiency is the most common primary immunodeficiency in humans. Its prevalence ranges from 1 in 100 to 1 in 1000 in among Arab populations. The majority of patients with selective IgA deficiency are asymptomat ic. The remaining present with recurrent upper and lower respiratory tract infections, recurrent gastrointestinal infections, otitis media, sinusitis, celiac disease, giardiasis, allergic disorders and some autoimmune diseases. to highlight the clinical manifestations and laboratory findings of Selective IgA deficiency in our study, and to compare it with medical literature. To study the bacterial complications and their prevalence. Materials & Methods: A retrospective study was carried out in Damascus University Children’s Hospital on sixteen child diagnosed as Selective IgA deficiency, in a period of the last ten years (from 2000 till September 2010). Results: most cases in our study were among males, failure to thrive was found in 75%, hepatosplenomegaly in one third, the most prominent infectious complications were: recurrent pneumonia (in 87.5% of cases), recurrent GI infections (in 75% of cases) and UTI’s in (50%)of cases. On the other hand, the celiac disease was found in (25%) of our patients, which is much higher than described in medical literature. In general, the infectious complications had a good response to antibacterial therapy, and the IgA levels became normal in one patient, when he reached the age of eleven years. Conclusion: there is no information in medical literature about the association of selective IgA deficiency with hepatomegaly, splenomegaly, failure to thrive and an increased prevalence of urinary tract infections, therefore, it is necessary to conduct researches about this association.
Field experiment was conducted during the season (2011 – 2012) at Bhanine village in Tartous city. Maize seeds of Ghouta 82 variety were planted in plastic pots filled with calcareous soil .Treatments including three levels of B (0, 3, and 6 kg.ha− 1) and four levels of Zn (0, 8, 16 and 24 kg.ha−1) added to the soil, in a completely randomized block design with three replications, to study the effect of different levels of boron and zinc and their interactions on maize content of some nutrients. Results of this study showed that there was a clear effect of B and Zn and their interactions in soil on leaf content of Mn, Fe and Cu. High amounts of zinc in the soil had a clear effect on reduced leaves content of B and increased its content of K. The presence of a of B in the soil, assisted to increasing of leaf N content. There was a significant effect of B and Zn interaction on leaf content of Zn, and no effect on leaf P content.
The study included 184 patients with type 2 diabetes referred to the specialist clinic or admitted in the sections of Al-Assad University Hospital in Damascus during the years 2012-2013. The patients were divided into three groups: Group A: a group of patients with diabetes is not treated with Metformin, 72 patients (39,1%). Group B: a group of patients with diabetes is treated with Metformin for more than 18 months, 72 patients (39,1%). Group C: a group of patients with diabetes is treated with Metformin for less than 6 months, 40 patients (21,8%). This study showed that 43,5% of the patients have Vit B12 deficiency: 32,6% of patients with diabetes treated with Metformin compared with 10,9% non treated with Metformin. The patients who were treated with Metformin (112 patients) were divided by dose intake and then depending on the duration of treatment into two groups for each category and shown an inverse correlation between duration and dose of therapy with metformin and levels of Vit B12. We also found that despite the increased risk of Vit B12 deficiency in patients with diabetes treated with Metformin but this was not associated with the occurrence of symptoms such as megaloplastic anemia and neurological symptoms.
Hypovitaminosis D is linked to osteomalacia , cardiovascular disease and some autoimmune diseases. Many studies showed that hypovitaminosis D is common worldwide, especially in the neighboring countries. The aim of this study is to determine serum concentrations of 25 hydroxyvitamin D3 in healthy Syrians, since vitamin D status in Syria is unknown.
Chin area is considered as a suitable donor site for autogenous bone grafts for alveolar ridge reconstruction before dental implantation. Despite the common use of chin bone grafts, some neurosensory deficiency of the of the lower lip, chin area , gingiva and lower anterior teeth may occur. Purpose: Evaluation of neurosensory deficiency of the lower lip, chin area , gingiva and lower anterior teeth following chin bone harvesting for posterior mandibular alveolar ridge reconstruction.
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