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Register a new userLow 25 Hydroxyvitamin D3 levels in healthy Syrians
نقص مستويات 25 هيدروكسي فيتامين د 3 لدى عينة من السوريين الأصحاء
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يرتبط نقص فيتامين د بالإصابة بالعديد من الأمراض منها تلين العظام و الداء القلبي الوعائي و بعض الأمراض المناعية الذاتية، و قد أظهرت دراسات عدة شيوع نقصه في العديد من بلدان العالم و لاسيما المجاورة لسورية. يهدف هذا البحث إلى دراسة المستويات المصلية ل 25 هيدروكسي فيتامين د 3 لدى عينة من السوريين الأصحاء بسبب نقص المعلومات حول واقع فيتامين د في بلادنا.
Hypovitaminosis D is linked to osteomalacia , cardiovascular disease and some autoimmune diseases. Many studies showed that hypovitaminosis D is common worldwide, especially in the neighboring countries. The aim of this study is to determine serum concentrations of 25 hydroxyvitamin D3 in healthy Syrians, since vitamin D status in Syria is unknown.
Artificial intelligence review:
Research summary
تهدف الدراسة إلى تقييم مستويات 25 هيدروكسي فيتامين د3 لدى عينة من السوريين الأصحاء، نظراً لقلة المعلومات المتاحة حول هذا الفيتامين في سوريا. أجريت الدراسة على 304 من مرافقي المرضى في مشفى الأسد الجامعي بدمشق، وتم قياس مستويات 25 هيدروكسي فيتامين د3 في مصل الدم. أظهرت النتائج أن 97.36% من المشاركين يعانون من نقص فيتامين د، و42.43% منهم يعانون من عوز شديد. كانت مستويات الفيتامين أقل لدى الإناث مقارنة بالذكور، وأقل لدى المحجبات مقارنة بغير المحجبات. توصي الدراسة بإجراء دراسات أوسع لتقييم نقص فيتامين د في سوريا بشكل أفضل.
Critical review
دراسة نقدية: على الرغم من أهمية الدراسة في تسليط الضوء على نقص فيتامين د في سوريا، إلا أنها تعاني من بعض القيود. أولاً، العينة المستخدمة قد لا تكون ممثلة بشكل كامل للسكان السوريين ككل، حيث تم اختيار المشاركين من مرافقي المرضى في مشفى واحد. ثانياً، لم يتم استخدام الطريقة المعيارية الذهبية لقياس مستويات فيتامين د، مما قد يؤثر على دقة النتائج. ثالثاً، لم يتم أخذ عوامل أخرى مؤثرة في الاعتبار مثل النظام الغذائي ومستوى النشاط البدني. لذا، من المهم إجراء دراسات أوسع تشمل عينات متنوعة واستخدام طرق قياس أكثر دقة.
Questions related to the research
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ما هو الهدف الرئيسي من الدراسة؟
الهدف الرئيسي هو تقييم مستويات 25 هيدروكسي فيتامين د3 لدى عينة من السوريين الأصحاء نظراً لقلة المعلومات المتاحة حول هذا الفيتامين في سوريا.
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ما هي نسبة المشاركين الذين يعانون من نقص فيتامين د؟
97.36% من المشاركين يعانون من نقص فيتامين د.
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هل كانت هناك فروقات في مستويات فيتامين د بين الجنسين؟
نعم، كانت مستويات الفيتامين أقل لدى الإناث مقارنة بالذكور.
-
ما هي التوصيات التي خلصت إليها الدراسة؟
توصي الدراسة بإجراء دراسات أوسع لتقييم نقص فيتامين د في سوريا بشكل أفضل.
References used
Gallagher M L. Vitamins. Mahan L K, Escott-Stump S. Krause`s Food, Nutrition& Diet Therapy 11TH ed :Saunders ,2004. 83-88
Bringhurst F R,Demay M B , Kronenberg H M. Hormones and disorders of mineral metabolism. Larsen P R, Kronenberg H M, Melmed Sh, Polonsky K S. Williams Textbook of Endocrinology. 10TH ed: Saunders, 2003.1317-1319
Shoback D,Marcus R, Bikle D. Metabolic bone diseases . Greenspan F S, Gardner D G. Basic &Clinical Endocrinology 7TH ed: Mc Graw- Hill Co, 2004.304-311
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