The aim of this study was to control the content of some commercial products containing amino acid (Arginine) available in the local market in addition to other products containing creatine and protein. Three methods were used for quantitative determ
ination of amino acids Kjeldahl method depending on the total content of nitrogen, assay by the visible radiation using Spectrophotometer after ninhydrin derivatization and high performance liquid chromatography with pre-column O-phtadelaldehyde derivatization using fluorescence detector. There were no significant differences in the results obtained by the three used methods. The results revealed that dietary supplements containing creatine and protein were conform to the European pharmacopoeia specifications, regarding products containing arginine used as medication and locally manufactured, they were conform to pharmacopoeia specifications while the illegal dietary supplement containing arginine were not conform.
An analytical chromatographic method for determination of total
benzalkonium chloride in eye drops preparations samples containing
gentamicin sulphate, tobramicin and viscous eye drops samples containing
fusidic acid has been developed.
Additive migration levels in food simulants from polymeric materials that
are intended to be into contact with food can be affected by additive stability
under the migration test conditions. In this work, the stability of four
antioxidants: Butyle
ted hydroxy toluene (BHT), Bisphenol A (BPA),
Pentaerythritol tetrakis (3,5-di-tert-butyl-4-hydroxyhydrocinnamate) (Irganox
1010), and Octadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl) propionate
(Irganox 1076), was studied in aqueous food simulants A, B, C and ethanol 95%
(as a substitute for olive oil- which is a fatty food simulant- simulant D), at
different temperatures 20, 40 and 70 ºC, during 20 days. Samples were
analyzed by high performance liquid chromatography (HPLC) with UV
detector. In general, the studied compounds appeared to be more stable in both
Ethanol (95%) and simulant B than in simulants A and C.
Additive migration levels in food simulants from polymeric materials that
are intended to be into contact with food can be affected by additive stability
under the migration test conditions. In this work, the stability of Dibutyl
adipate (DBA), Di
isobutyl adipate(DIBA), Diisobutyl phthalate (DIBP), Di-noctyl
phthalate (DnOP),and Diethylhexyl sebacate (DEHS).,was studied in
aqueous food simulants A, B, C and ethanol 95% (as a substitute for olive oilwhich
is a fatty food simulant, simulant D), at different temperatures 20, 40 and
70 ºC, during 20 days. Samples were analyzed by high performance liquid
chromatography (HPLC) with UV detector at 270 nm. The stability of the
studied compounds appeared to be least of all in simulant B, then in simulant
A, and finally in simulant C., When temperature and exposure time increase.,
on the other hand, the increase in temperature and exposure time have greatly
less effect on the stability of plasticizers in ethanol %95,as a substitute for olive
oil-which is a fatty food simulant.
Additive migration levels in food simulants from polymeric materials that
are intended to be into contact with food can be affected by additive stability
under the migration test conditions. In this work, the stability of two
plasticizers: Diethyl
hexyl phthalate (DEHP) and Dibutyl phthalate (DBP) was
studies in aqueous food simulants A, B, C and ethanol 95% (as a substitute for
olive oil- which is a fatty food simulant- simulant D), at different temperatures
20, 40 and 70 C0, during 20 days. Samples were analyzed by high performance
liquid chromatography (HPLC) with UV detector.
In general, DEHP and DBP plasticizers appeared to be more stable in both
Ethanol (95%) and simulant C than in simulants A and B, while, they are less
stable, even at low temperatures, in Simulant B than in simulant A .
In the present work, batch electrocoagulation experiments were carried out
to evaluate the removal of polycyclic aromatic hydrocarbon (PAHs) from water
using aluminum electrodes. The effects of initial pH, current density,
electrolysis time, initi
al concentration of PAHs, electrolyte type, and electrolyte
concentration were investigated to achieve the optimal removal efficiency. The
results indicated that the electrocoagulation utilizing the aluminum, as anode
and cathode, was an efficient tool in the reduction of these contaminants. The
treatment process was found to be largely affected by the current density and
the initial composition of water. The removal rate was significantly increased
using NaCl as an electrolyte where indirect oxidation by hypochlorite forming
later during the treatment was occurred. The results demonstrated that the
technical feasibility of the electrocoagulation as a possible and reliable
technique for the treatment of PAHs contaminants in water.
A simple and accurate method was developed for the analysis of
carbinoxamine maleate, dextromethorphan hydrobromide and
pseudoephedrine hydrochloride content in pure form and pharmaceutical
preparations using HPLC. Analysis was conducted on a sili
ca column (6 μm)
with mobile phase consisting of ethanol – ammonium acetate (0.05 M) in rate
[85:15] respectively, and at detection wavelength of 276 nmand flow rate 1ml/ min.
Results were linear (correlation coefficient R > 0.9996) in the range of the
studied concentrations for the active materials. The relative standard
deviations (n=6) of intra and interday assay were 0.931%, 1.527% for
carbinoxamine maleate and 0.717%, 1.058 % for dextromethorphan
hydrobromide and 0.309%, 0.891% for pseudoephedrine hydrochloride,
respectively. This method, proved to be easy, precise and economical, is useful
for quality control of pharmaceutical drugs industrial samples.
A new analytical method has proposed for determination of
five synthetic colorants used in the wine industry (i.e., Tartrazine,
Brilliant Black, Sunset yellow, Brilliant Blue and Erythrosine) by
reversed-phase high-performance liquid chromatograph
y equipped
with Diode Array detector.
Experimental conditions, including spectral properties, limits
of detection and recoveries for these synthetic colorants in detail
were studied and assigned according to the statistical methods
adopted.
