An analytical chromatographic method for determination of total
benzalkonium chloride in eye drops preparations samples containing
gentamicin sulphate, tobramicin and viscous eye drops samples containing
fusidic acid has been developed.
Mixtures of ammonium acetate and ammonium tartrate in the presence of
benzyl alkyl dimethyl ammonium chloride (benzalkonium chloride) were used
for sealing sulphuric acid anodized aluminium.
Mixtures of ammonium acetate and ammonium tartrate exhib
ited
synergistic sealing effect, which offered excellent durable corrosion protection
to the surface coating formed by anodizing the aluminium alloy. Moreover the
synergistic effect of benzalkonium chloride with tartrate offered boehmite free
sealed surface coating.
Quality and durability of the sealed aluminium oxide films have been
assessed using standard control sealing quality tests and well-known
salt- spray (fog) test (ASTM B 117-97).