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An analytical chromatographic method for determination of total benzalkonium chloride in eye drops preparations samples containing gentamicin sulphate, tobramicin and viscous eye drops samples containing fusidic acid has been developed.
Mixtures of ammonium acetate and ammonium tartrate in the presence of benzyl alkyl dimethyl ammonium chloride (benzalkonium chloride) were used for sealing sulphuric acid anodized aluminium. Mixtures of ammonium acetate and ammonium tartrate exhib ited synergistic sealing effect, which offered excellent durable corrosion protection to the surface coating formed by anodizing the aluminium alloy. Moreover the synergistic effect of benzalkonium chloride with tartrate offered boehmite free sealed surface coating. Quality and durability of the sealed aluminium oxide films have been assessed using standard control sealing quality tests and well-known salt- spray (fog) test (ASTM B 117-97).
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