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Register a new userStudy of Empty Sella Syndrome in Al-Assad University Hospital
دراسة متلازمة السرج التركي الفارغ في مشفى الأسد الجامعي بدمشق
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يونس محمد قبلان( باحث )
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السرج التركي الفارغ البدئي متلازمة شعاعية لا عرضية عادة، تصيب 6 % من النساء بعـد الإياس، يمكن أن تشاهد في جميع الأعمار. تشابهت بعض نتائج دراستنا مع الدراسات العالمية في كثير من الأمور، كوجودها بمختلـف الأعمار و لاسيما عند الأطفال، و ترافقها مع البيلة التفهة بنسبة 97.5 % و اختلفت عنها مـن حيث زيادة نسبة فرط البرولاكتين، التي بلغت بدراستنا 2.58 % (في حين لا تتجاوز 7.33% بالدراسات الأخرى)، لم نصادف حالات من الأورام النخامية المفرزة (تذكر الدراسات وجود ضخامة النهايات و متلازمة كوشيغ بنسبة 6.2 % لكل منهما ) لم نصادف أي حالة سيلان سائل دماغي شوكي من الأنف، كما لم نسجل اضطرابات بصرية لدى مرضانا تلقى المرضى معالجة عرضية و لم نضطر لإرسال أي من مرضانا للجراحة.
The empty sella syndrome (ESS) is an asymptomatic radiological syndrome, affecting 6% of post-menopausal women and can be seen in all ages. The results were similar with other studies in many respects, such as a wide age spectrum including children, and the occurrence of diabetes insipidus in 5.97%. The results of our study were discordant with other studies with respect to hyperprolactinemia which reached 58.2% in our study (in other studies did not exceed 33.7%). No concurrent cases of secretory pituitary adenomas were found (studies refer to an incidence of acromegaly and Cushing’s syndrome in 2.6% of ESS for each). We did not record CSF rhinorrhea nor were visual disturbances seen in our cohort. Patients received symptomatic treatment and none were referred to surgery.
Artificial intelligence review:
Research summary
تتناول هذه الدراسة متلازمة السرج الفارغ (ESS) في مستشفى الأسد الجامعي، وهي متلازمة إشعاعية غير عرضية تؤثر على 6% من النساء بعد انقطاع الطمث ويمكن رؤيتها في جميع الأعمار. شملت الدراسة 67 مريضًا تم تشخيصهم بـ ESS الأولي، حيث تم استبعاد حالات ESS الثانوي. كان متوسط عمر المرضى 29.3 عامًا، مع نطاق عمري من 7 إلى 53 عامًا. كانت النسبة الأكبر من المرضى من الإناث (76.11%) مقارنة بالذكور (23.88%). من بين المرضى الذين تقل أعمارهم عن 18 عامًا، كان هناك 10 حالات تأخر في النمو، و5 حالات من خلل في الغدة النخامية الأمامية، ووجود السرج الفارغ في التصوير بالرنين المغناطيسي. كانت السمنة موجودة في 80.39% من النساء و25% من الرجال. كانت الصداع موجودة في 53.73% من المرضى. أظهرت النتائج تباينًا مع الدراسات الأخرى فيما يتعلق بفرط برولاكتين الدم، حيث وصلت نسبته إلى 58.2% في هذه الدراسة مقارنة بـ 33.7% في الدراسات الأخرى. لم تُسجل حالات من الأورام النخامية الإفرازية أو تسرب السائل النخاعي أو اضطرابات بصرية في هذه الدراسة. تلقى المرضى علاجًا عرضيًا ولم يُحال أي منهم إلى الجراحة.
Critical review
دراسة نقدية: تقدم هذه الدراسة نظرة شاملة ومفصلة حول متلازمة السرج الفارغ (ESS) في مستشفى الأسد الجامعي، وتسلط الضوء على العديد من الجوانب الهامة مثل التوزيع العمري والجنساني والأعراض المصاحبة. ومع ذلك، يمكن توجيه بعض النقد البنّاء لتحسين الدراسة. أولاً، كان من المفيد توفير مزيد من التفاصيل حول منهجية البحث وكيفية اختيار العينة لضمان تمثيلها الدقيق للسكان. ثانيًا، كان من الممكن تضمين مقارنة أكثر تفصيلًا مع الدراسات السابقة لتوضيح أسباب التباين في النتائج، خاصة فيما يتعلق بفرط برولاكتين الدم. وأخيرًا، كان من الممكن تقديم توصيات أكثر وضوحًا للعلاج والمتابعة لتحسين إدارة المرضى في المستقبل.
Questions related to the research
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ما هي النسبة المئوية للنساء المصابات بالسمنة في هذه الدراسة؟
النسبة المئوية للنساء المصابات بالسمنة في هذه الدراسة هي 80.39%.
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ما هو متوسط عمر المرضى الذين شملتهم الدراسة؟
متوسط عمر المرضى الذين شملتهم الدراسة هو 29.3 عامًا.
-
هل تم تسجيل أي حالات من الأورام النخامية الإفرازية في هذه الدراسة؟
لم تُسجل أي حالات من الأورام النخامية الإفرازية في هذه الدراسة.
-
ما هي نسبة المرضى الذين يعانون من الصداع في هذه الدراسة؟
نسبة المرضى الذين يعانون من الصداع في هذه الدراسة هي 53.73%.
References used
Bjerre P. The empty sella : A reappraisal of etiology and pathogenesis. Acta Neurol Scand 1990; 130 (Suppl): 1-25
Schaeffer JP: Some points in the regional anatomy of the optic pathway with special reference to tumors of the hypophysis cerebri and resulting ocular changes. Anat Rec 28:243--279, 1924
Empty Sella Syndrome. Journal, Indian Academy of Clinical Medicine Vol. 2, No. 3 July-September 2001
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Introduction 7 Visceral Leishmaniasis( VL )is characterized by a spectrum of
clinical features, with high cure rates in early diagnosis.
Objective: the objective is to describe the clinical and epidemiological features and
laboratory variables of
children with visceral leishmaniasis ,And to define the importance
of a positive direct investigation of the parasite in Bone marrow in the diagnosis of disease
.
Patients and Methods : It was a case series study of )52( cases of Visceral
Leishmaniasis which were hospitalized between June-20 31and June-2014 in Al -Assad
University Hospital ,Latakia
Results 52 7 7 children were included in this study .Majority of the patients (92%)
presented with fever ,common findings in physical examination were(100%) Pallor and
(97%) splenomegaly
The direct investigation of parasite in Bone marrow was positive in )%55( of cases .
The study included 77 patients admitted to Pediatric Department in AL-ASSAD
University Hospital in Lattakia for doing therapeutic gastroendoscopy between ( Jul
2009-Jul 2014),number of procedures were (195) with age ranging between( 1mon-16 y)
and
The main indication of interventional GI endoscopy in this series was foreign body
extractions, oesophageal stenosis, esophageal varices ligation followed by polyp resection
and Management of rectal prolapse refractory.
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complet cure percent was high (64,4%), but (26%) of cases are followed up and good
until now, there were Two patients of oesophageal dilatation may need surgical
interference.
Compliance of health care workers to adhere to correct hand hygiene is reported to
be poor in many countries although the techniques involved in hand hygiene are simple.
This study yielded interesting findings regarding knowledge and behavior among
a sample
of 30 nurses in Al-assad university hospital in Lattakia. Nurses received a self administered
paper questionnaire on knowledge and practices of hand hygiene at their workplace and
were observed during their work. Only (14 %) of participants had very good knowledge
about hand hygiene, with a significant difference in the level of knowledge according to
the level of education as respondents with university degree were more likely to correctly
identify the proper way of hand hygiene compared to those nurses who have a lower level
of education. On the other hand, the overall hand hygiene compliance among nurses is
30%. Some of the key parameters associated with noncompliance have been clearly
identified. Hand washing hygiene is a cheap and primary infection control procedure.
Therefore, the study suggests some improvement by continuous education during shifts,
seminars and posters, ensuring the availability of adequate hand washing utilities like soap,
water taps, drying tissues and reducing work load to improve nurse to patient ratio.
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