In this research two analytical methods were developed for the determination of Azelastin as raw material and in Nasal Spray formulation.
The first method was spectrophotometric while the other used the technic of HPLC The first method based on meas
uring the absorbance at λmax 284 nm .
The relationship between the absorbance and the concentration is rectilinear over the range 0.001 – 0.008 g %.
The proposed spectrophotometric method was successfully applied to the determination of Azelastin in nasal spray.
The percentage recoveries were 99.378±1 (10 duplicate readings)1
No interference was noticed from co-formulated drugs.
For the absorbance at λmax the obtained results were in good agreement with which obtained by the Pharmacopeia method.
The substance gave a good separation while the retention time was 1.467 min.
The aim of this study was evaluation the effective of chelating
solutions 17% EDTA, 0.2% Chitosan and 10% Sodium citrate by
comparing the concentrations of chelated calcium ions after
(1min-5min-24h) of application. The study was performed on 45
extracted single-rooted sound human. The sample was randomly
divided into groups (n=3), each group 15 teeth that depend on the
used solution.
Benzoic acid is extensively used in the preservation of food products for maintaining
quality and extending shelf life by inhibiting mould and bacteria growth.
Some previous studies have demonstrated that consumption of excessive amounts of
benzoi
c acid could be a health hazard.
The aim of this study was to detect the presence of benzoic acid and its salts in
some commercial children food like potatochips that labeled "Free of Preservatives" .
Twenty seven samples of potatochips purchased from three different local products
were analyzed for the presence of benzoic acid.
The results revealed the presence of benzoic acid in nine samples and its
concentration was between 100.34-188.65mg/kg.
We have concluded also that TLC is a very convenient method for the
detection of benzoic acid in food products .
Breast cancer is one of the most common cancers in women;
one of nine women will have breast cancer in her life time.
Tamoxifen is the trans-isomer of a triphenylethylene derivative.
The aim of this study is to evaluate the quality and the quantit
y of the
commercial brands of Tamoxifen 10 mg tablets which are registered and
marketed in Yemen.
Fluoride ion is present in high concentration in some regions in Syria. As
fluoride occurs naturally in water, We have studied some methods of fluoride
removal such as Nalgonda technique and activated carbon method.
In Nalgonda technique we add Al
um and lime to the water, and we have
found that fluoride removal efficiency remains constant when the initial
concentrations of fluoride changes, or when the chloride ions exists in water,
but it depends on pH, and get better when the method is investigated in two
steps. In addition, adsorption of fluoride decreases with increasing
sedimentation time, or using Ventilated lime or CaCO3 instead of Ca (OH)2.
In activated carbon method we have done different experiments by using
charcoal of coconut coir, date seeds and olive seeds. And we have found that
olive seeds carbon is better than others, and its fluoride removal efficiency
increases after impregnation with solution of 2% Al2(SO4)3.
Four different brands of black tea and one brand of green tea commonly
available in Syrain markets were tested to measure the level of fluoride
contained in their liquid using four different methods of infusion and utilizing
the spectrophotometer
technology: A. Infusion without boiling. B. Infusion with
boiling. C. Repeated infusion. D. Continuous infusion.
The results have indicated that the average level of fluoride in the samples
of black tea liquid is higher than the one in the green tea sample regardless of
the infusion method used. Also, it was found that the level of fluoride released
from all samples is higher when boiling them in water from 1 to 5 minutes. In
addition, it was proved that the level of fluoride in tea liquids is higher when
it’s prepared using repeated infusion, but it’s lower when the tea has been
prepared using the continuous infusion method. Tea brands (2) and (4) released
the highest level of flouride 7.37mg/L and 5.01mg/L respectively, which are
very high levels comparing to the other brands which released between 1.5mg/L
to 2.7mg/L. To prevent fluoride from reaching poising levels, the total daily
consumption of black tea liquid of brands (2) and (4) should not exceed 1.76L
and 2.58L respectively and to avoid preparing them using the repeated and
countinous infusion methods.
The research was performed by isolating some species of soil- fungi from agricultural soils
handling with different pesticides and fungicides. Where the following fungi were isolated:
Aspergillus niger (The isolates A1 and A2), Fusarium oxysporum (
The isolate F),
Trichoderma harzianum (The isolate T). Also F. solani (The isolate F7) and T. viride (The
isolate T.v) were used, whereas they were taken from high studies laboratory- Science
Faculty- Tishreen University at a previous search.
The research was conducted to assay the ability of the previous fungi to degradation a
number of pesticides, the insecticide "Dolan", the insecticide "Plantocide", the nematicide
"Vydate" and the fungicide "Bayfidan", through the effect of double dose of each
pesticides in the biomass of the studied fungi on PDB medium. In addition to analysis the
results residues of pesticides using Spectrophotometer, and evaluation the pH values.
