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Lichen (Lecanora epibryon) collected from Arshany reservation at Idleb city was taken for screening antibacterial activity. Acetone was used as solvent for extraction of active compounds from lichen. The activity of extract was tested against thre e isolated infectious bacteria (Pseudomonas sp., Salmonella sp., Klebsiella sp.) by cytotoxicity assay using MTT test. Acetone extract of lichen showed antibacterial activity against all test organisms, but Salmonella sp. was highly susceptible to the extract even at low concentration.
The study aims to determine the Seroprevalence of anti-H. pylori antibodies in patients with peptic complaints using indirect immunofluorescence assay (IFA), and compare serology with histological examination of biopsies from upper gastrointestinal e ndoscopy to evaluate the sensitivity and specificity of this assay. The Study sample included 120 participants divided into two groups: 69 patients with peptic complaints who underwent upper GI endoscopy in Al-Assad Hospital in Lattakia (average age 47 years old), and 51 volunteers without peptic complaints (average age 33 years old). The study was conducted in the period between February 2011 and March 2012. Indirect immunofluorescence assay (IFA) was used to study the seroprevalence of anti-H. pylori antibodies and fluorescence intensity in the two groups. The results showed that 63 of the patients group (91.3%) and 39 of volunteers (76.47%) are anti-H. pylori antibodies positive. The comparison of serology with histological examination of biopsies showed a sensitivity and specificity of 78% and 80% respectively in the presence of moderate and strong degree of fluorescence. The results reveal the importance of IFA as a non-invasive screening test besides the endoscopy, and the utility of this technique for the epidemiologic studies in a local setting.
Hypovitaminosis D is linked to osteomalacia , cardiovascular disease and some autoimmune diseases. Many studies showed that hypovitaminosis D is common worldwide, especially in the neighboring countries. The aim of this study is to determine serum concentrations of 25 hydroxyvitamin D3 in healthy Syrians, since vitamin D status in Syria is unknown.
Breast cancer is one of the most common cancers in women; one of nine women will have breast cancer in her life time. Tamoxifen is the trans-isomer of a triphenylethylene derivative. The aim of this study is to evaluate the quality and the quantit y of the commercial brands of Tamoxifen 10 mg tablets which are registered and marketed in Yemen.
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