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Bioeffect of some Syrian Myrtus communis L. leaves extracts in the growth of some pathogenic microorganisms

التأثير الحيوي لبعض مستخلصات أوراق نبات الآس الشائع السوري .L communis Myrtus في نمو بعض الأحياء الدقيقة الممرضة

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 Publication date 2012
  fields Biology
and research's language is العربية
 Created by Shamra Editor




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Bioeffect of some Syrian Myrtus communis L. leaves extracts in growth of some pathogenic microorganisms, which were isolated from Al-Assad hospital laboratory in Lattakia, was tested by disc diffusion method. Results showed that cold and hot water extracts have antibacterial activity against all Gram positive and negative bacteria, and pathogenic Candida albicans except Klebsiella pneumoniae. All organic extracts have antibacterial activity against Proteus vulgaris, Entrococcus faecium, Staphylococcus aureus and Staphylococcus albus. Pseudomonas aeruginosa and Pseudomonas fluorescens were affected by most of the organic extracts, and the most bioactivity was by methanol extract, and all inhibition zones of extracts were bigger than inhibition zones by control antibiotics. Serratia marcescens and Acinetobacter calcoaceticus were affected by methanol (with highest inhibition zone 37.33 and 27.33 mm respectively), ethanol, acetone and ethyl acetate extracts, but resistant to the others. Klebsiella pneumoniae affected by ethanol extract only with inhibition zone 20.33 mm. Results of bioactivity according to a various solvents used in this study demonstrate that Syrian Myrtus communis L. leaves extracts have antimicrobial activity, so expected to be potential sources of natural antibacterial and antifungal products against some pathogenic bacteria and fungi in the future.


Artificial intelligence review:
Research summary
تتناول هذه الدراسة تأثير مستخلصات أوراق نبات الآس الشائع السوري Myrtus communis L. على نمو بعض الأحياء الدقيقة الممرضة. تم اختبار المستخلصات باستخدام طريقة الانتشار بواسطة الأقراص على عينات معزولة من مختبر مستشفى الأسد الجامعي في اللاذقية. أظهرت النتائج أن المستخلصات المائية الباردة والساخنة تمتلك فعالية مضادة للبكتيريا السلبية والإيجابية غرام والفطريات الممرضة Candida albicans باستثناء بكتيريا Klebsiella pneumoniae. كما أظهرت المستخلصات العضوية فعالية ضد بكتيريا Proteus vulgaris وEntrococcus faecium وStaphylococcus aureus وStaphylococcus albus، وكانت بكتيريا Pseudomonas aeruginosa وPseudomonas fluorescens حساسة لمعظم المستخلصات العضوية. كان مستخلص الميتانول الأكثر فعالية، حيث كانت أقطار حلقات تثبيط النمو الميكروبي أكبر مقارنة بالمضادات الحيوية المستخدمة كشاهدة. تشير الدراسة إلى أن مستخلصات أوراق نبات الآس الشائع يمكن أن تكون مصدراً محتملاً للمضادات الحيوية الطبيعية ضد بعض البكتيريا والفطريات الممرضة في المستقبل.
Critical review
دراسة نقدية: على الرغم من أن الدراسة تقدم نتائج مشجعة حول فعالية مستخلصات أوراق نبات الآس الشائع، إلا أن هناك بعض النقاط التي تحتاج إلى مزيد من التوضيح. أولاً، لم يتم توضيح التركيزات الدقيقة للمستخلصات المستخدمة في الاختبارات، مما يجعل من الصعب تكرار الدراسة بدقة. ثانياً، لم يتم اختبار تأثير المستخلصات على مجموعة واسعة من الأحياء الدقيقة الممرضة، مما يحد من تعميم النتائج. ثالثاً، لم يتم مناقشة الآثار الجانبية المحتملة أو السمية للمستخلصات على الكائنات الحية الأخرى، وهو أمر مهم قبل التفكير في استخدامها كعلاج. وأخيراً، كان من المفيد إجراء مقارنة بين فعالية المستخلصات المختلفة لتحديد أي منها الأكثر فعالية بشكل قاطع.
Questions related to the research
  1. ما هي الأحياء الدقيقة التي أظهرت مقاومة للمستخلصات المائية والعضوية؟

    بكتيريا Klebsiella pneumoniae أظهرت مقاومة للمستخلصات المائية والعضوية باستثناء مستخلص الإيتانول.

  2. ما هو المستخلص الأكثر فعالية في تثبيط نمو الأحياء الدقيقة الممرضة؟

    كان مستخلص الميتانول الأكثر فعالية في تثبيط نمو الأحياء الدقيقة الممرضة.

  3. هل كانت هناك أي أحياء دقيقة حساسة للمستخلصات المائية الباردة فقط؟

    نعم، بكتيريا Escherichia coli كانت حساسة للخلاصة المائية الباردة ولكنها أظهرت مقاومة للخلاصة المائية الساخنة.

  4. ما هي الفطريات التي تم اختبارها في هذه الدراسة؟

    تم اختبار فطريات Candida albicans في هذه الدراسة.


References used
-Chanthaphon, S.; Chanthachum, S. and Hongpattarakere, T., 2008. Antimicrobial activities of essential oils and crude extracts from tropical Citrus spp. against food-related microorganisms. Songklanakarin J. Sci. Technol., Vol. 30, pp. 125-131
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