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Register a new userDetection of E. coli in Different Body Samples and Its Sensitivity to Antibiotics
التحري عن الإشريكية القولونية في العينات المرضية المختلفة و حساسيتها للصادات الحيوية
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Aِl-Baath University ورقة بحثية
Publication date
2017
fields
Life Science
and research's language is
العربية
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Shamra Editor
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تم جمع 204 عيّنة من عينات الجسم المختلفة خلال عام 2016 توزعت على الشكل التالي : 133 عيّنة من البول ، 37 عيّنة من حروق و جروح ، 10 عيّنات من أذن و بلعوم ، 12 عيّنة من البراز ، 8 عيّنات من السائل الدماغي الشوكي (CSF), عيّنات من الدم . أوضحت الدراسة سيادة سلبيات الغرام و قد بلغ عدد عزلاتها 136 بنسبة 67 % مقابل إيجابيات الغرام التي بلغ عدد عزلاتها 68 بنسبة %33 و سيطرت الإشريكية القولونية بنسبة 39.68 % من مجموع عزلات الجراثيم سلبية الغرام. أظهرت الدراسة زيادة نسبة مقاومة الإشريكية القولونية لنوع أو أكثر من الصادات الحيوية ، فقد بلغت مقاومتها 100 % للجيل الثاني و الثالث و الرابع من السيفالوسبورينات. كما أظهرت الدراسة بوضوح ظهور مقاومة لصادات نوعية و فعالة مثل الإيميبينيم.
204 samples were collected from various body samples during the year 2016. These 204 samples distributed as follows: 133 from urine , 37 swabs of wounds and burns, 10 swabs from the ear and pharynx, 12 from feces, 8 from CSF, 4 from blood. This study distinctly showed that gram negative bacilli were the most isolates 136 (67%) while 68 isolates (33%) were gram positive bacteria . E. coli dominated (39.68%) of the total gram negative bacilli. This study distinctly showed an increase in the ratio of E. coli resistance to one or more types of antibiotics , we found that E. coli resistance to all antibiotics except specific and expensive antibiotics, and we found that its complete resistance to the second ,third and fourth generation of cephalosporins , resistance to specific and antibiotics such as Imipenem.
References used
Abduzaimovic A, Rebic V, et al. (2016). Antibiotic resistance in urinary isolates of e. coli. Journal of the academy of medical science Bosnia and Herzegovina. Vol. 28, no. 6, p. 416- 419
Akingbade O, Balogun S O, et al. (2014). Resistant plasmid profile analysis of multidrug resistant e. coli isolated from urinary tract infection in Abeokuta, Nigeria. African health sciences, vol. 14, no. 4
Asit kumar chakraborty. (2016). Multidrug-resistance genes in bacteria and 21st century problems associated with antibiotic therapy. Biotechnol Ind J, vol. 12, no. 12, p. 114
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Twenty plant and animal food samples were collected from
different commercial stores. These samples were placed in a
sterilezed plastic bags not to be polluted and were moved to the
laboratory in special thermal containers to be tested.
The solid
samples were processed in the Digester to study each
sample separately , while the liquid samples were tested
immediately after being diluted.
After that they were studied with biochemical tests to identify the
type of germ that existed.
Bacterial pathogens associated with urinary tract infection were
studied. The study examined 120 urine samples taken from the middle
of the urinary flow of patients with symptoms of urinary tract infection.
عندما تكتسب الجراثيم مقاومة للعقاقير الصادة لها تتقلص الخيارات المتاحة لمعالجة ما تسببه من أمراض والواقع أن هذه الظاهرة باتت ظاهرة عالمية تشمل طائفة عريضة من الجراثيم الممرضة
This research aims to investigate the effectiveness of anti-bacteria shown by the extracts prepared from
per carps of different types of Punica granatum ( L) ( from the family Punicaceae), which grow in Syria
against Escherichia coli (E.coli) biotype (1), which were resistant to studied antibiotics.
20 antibiotics were monitored for their sales for six months, through official
prescriptions in six drug stores throughout Lattakia. Percent proportions of
sale for each antibiotic were reported. These statistical data were correlated
with laborat
ory studies on screening these antibiotics on different bacterial
strains that collected from different laboratories and hospitals of Lattakia.
The purpose of this continuous study is to undertake an assessment of levels
of antibiotic resistance by local isolated bacteria, and to determine the
factors influencing the offspring of that resistance.
1430 medical prescriptions were reported, 965 of them (i.e.: 67, 48%)
contained one or more antibiotic. In addition, there were 340 cases of nonofficial
sales of some distinct antibiotics.
275 of bacterial strains were isolated from clinical specimens (mostly were
as urogenital, pharyngeal, wounds, and burns infections). These strains
distributed as follow: 183 (i.e.: 66, 54%), were Enterobacteriaceae strains.
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