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Study of the Anti Bacterial Effect of the Pericarps of Many Varieties of Punica Granatum on E.Coli Biotype (1) Which Reveal Resistance Toward Many Antibiotics

دراسة التأثير المضاد لقشر ضروب مختلفة لنبات الرمان في جراثيم الإشريكية القولونية النمط الحيوي (1) التي أبدت مقاومة للعديد من الصادات الحيوية

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 Publication date 2011
and research's language is العربية
 Created by Shamra Editor




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This research aims to investigate the effectiveness of anti-bacteria shown by the extracts prepared from per carps of different types of Punica granatum ( L) ( from the family Punicaceae), which grow in Syria against Escherichia coli (E.coli) biotype (1), which were resistant to studied antibiotics.


Artificial intelligence review:
Research summary
تتناول هذه الدراسة تأثير المستخلصات المحضرة من قشور أنواع مختلفة من نبات الرمان على جراثيم الإشريكية القولونية النمط الحيوي (1) التي أبدت مقاومة للعديد من الصادات الحيوية. تم جمع 843 عينة حليب من أبقار مصابة بالتهاب الضرع في سوريا، وتم تحديد الجراثيم باستخدام منابت مختلفة واختبارات كيميائية حيوية. تم استخراج قشور الرمان باستخدام الماء، الكحول المطلق، والإيثر، وتم اختبار فعالية هذه المستخلصات ضد الجراثيم باستخدام طريقة الانتشار من الأقراص الورقية. أظهرت النتائج أن نسبة جراثيم الإشريكية القولونية النمط (1) كانت 33.35% من العينات، وأن المستخلصات المحضرة من قشور الرمان أظهرت فعالية مضادة لهذه الجراثيم، في حين لم تظهر الصادات الحيوية المدروسة أي تأثير مضاد. توصي الدراسة بإجراء بحوث إضافية لدراسة تأثير أنواع الرمان الأخرى على الجراثيم المقاومة للصادات الحيوية وتحديد المكونات الفعالة وتركيزاتها لإيجاد بدائل علاجية فعالة.
Critical review
دراسة نقدية: تقدم هذه الدراسة إسهامًا مهمًا في البحث عن بدائل طبيعية للصادات الحيوية التقليدية التي تواجه مشكلة مقاومة الجراثيم. ومع ذلك، هناك بعض النقاط التي يمكن تحسينها. أولاً، كان من الأفضل تضمين عدد أكبر من العينات لتأكيد النتائج بشكل أكبر. ثانيًا، لم يتم تحديد المكونات الفعالة في مستخلصات الرمان بشكل دقيق، مما يجعل من الصعب تحديد الآلية التي تعمل بها هذه المستخلصات. أخيرًا، كان من الممكن توسيع نطاق الدراسة لتشمل أنواعًا أخرى من الجراثيم المقاومة للصادات الحيوية لتقديم صورة أكثر شمولية.
Questions related to the research
  1. ما هي نسبة جراثيم الإشريكية القولونية النمط (1) من العينات الكلية؟

    كانت نسبة جراثيم الإشريكية القولونية النمط (1) 33.35% من العينات الكلية.

  2. ما هي الطرق المستخدمة لاستخلاص قشور الرمان في الدراسة؟

    تم استخلاص قشور الرمان باستخدام الماء، الكحول المطلق، والإيثر باستخدام جهاز سوكسلية وجهاز مبخر التخلية الدوار.

  3. هل أظهرت الصادات الحيوية المدروسة أي تأثير مضاد على الجراثيم؟

    لم تظهر الصادات الحيوية المدروسة أي تأثير مضاد على الجراثيم.

  4. ما هي التوصيات التي قدمتها الدراسة؟

    توصي الدراسة بإجراء بحوث إضافية لدراسة تأثير أنواع الرمان الأخرى على الجراثيم المقاومة للصادات الحيوية وتحديد المكونات الفعالة وتركيزاتها لإيجاد بدائل علاجية فعالة.


References used
Pradeep B.V, Manojbabu M.K, Palaniswam M. Antibacterial Activity of Punica granatum L. against Gastro Intestinal Tract Infection Causing Organisms. Ethnobotanical Leaflets 12: 1085-89. 2008
Nair R ، Chanda S .Antibacterial Activity Of Punica Granatum In Different Solvents. Indian Journal of Pharmaceutical science. Vol.67( 2) ، 239-243، 2005
Ahmet D, Ozgen M, Kenan S.Antimicrobial Activity of Six Pomegranate (Punica granatum L.) Varieties and Their Relation to Some of Their Pomological and Phytonutrient Characteristics. Molecules 2009، 14(5)، 1808- 1817
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