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Register a new userMorphological Studying of Urinary Bladder Specimens During 3 Years in Al-Assad University Hospital in Lattakia
دراسة مورفولوجيّة لعيّنات المثانة خلال 3 سنوات في مشفى الأسد الجامعي في اللّاذقية
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Tishreen University ورقة بحثية
Publication date
2015
fields
Medicine
and research's language is
العربية
Authors
عيسى يوسف أحمد( باحث )
Created by
Shamra Editor
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الأورام المثانية الخبيثة هي من الأورام الأكثر شيوعاً عبر العالم، تشخيص سرطانه المثانة في مراحل تطورها المتقدم يدفع الطبيب إلى اختيار استئصال المثانة الجذري، من العناوين المدروسة التشخيص الدقيق و التنميط النسيجي و تحديد درجة و مرحلة الورم المثاني، بغية الحصول على علاج و إنذار أفضل. تمت الدراسة المورفولوجية لعينات المثانة بالطرق الروتينية. فكان عدد الخزع 250 مأخوذة من 194 مريض (منهم ذكور 172، إناث 22). الأورام ذات الدرجة المنخفضة 41 و العالية 149 ورماً. بالرغم من أن عدد الأورام المشخصة في المراحل المبكرة 138 و المتأخرة 66، فإنّه يجب دوماً الحرص على التشخيص الباكر لأجل حياة أفضل بعد المعالجة. قد يكون من المفيد في المستقبل التحرّي و البحث عن أسباب غلبة المرضى الذكور في أورام المثانة، و كذلك تبيان دور الالتهابات المثانية المختلفة في تطور سرطانه المثانة.
The urinary bladder malignant neoplasms are the member of the most common malignancies through the world. The diagnosis of bladder carcinoma in its late advanced development evokes the surgeon to radical cystectomy. The studying points are the correct diagnosis, histological types, histological grade and pathological stage of the disease, in order to achieve the best treatment and prognosis. The morphological examination of bladder biopsies were done routinely, the total biopsies were 250, obtained from 194 patients (172 male, 22 female). The low grade tumor were 41, and high grade 149.although the early stage diagnosis were 138, and the late stage 66, always we must detect the lesion early for the best life after the treatment. may be useful in the future study and detect the reason of predominance the male gender in bladder tumor, also we hope, that we can discover the role of inflammation in arising the neoplasm of bladder.
Artificial intelligence review:
Research summary
تناولت هذه الدراسة المورفولوجية عينات من المثانة خلال ثلاث سنوات في مشفى الأسد الجامعي في اللاذقية. الأورام المثانية الخبيثة تُعد من أكثر الأورام شيوعاً في العالم، وتشخيصها في مراحل متقدمة يدفع الأطباء إلى استئصال المثانة الجذري. تم تحليل 250 خزعة من 194 مريضاً (172 ذكور و22 إناث)، حيث كانت الأورام ذات الدرجة المنخفضة 41 والعالية 149. تم تشخيص 138 حالة في المراحل المبكرة و66 حالة في المراحل المتأخرة. تشير النتائج إلى أهمية التشخيص المبكر لتحسين فرص العلاج والإنذار. كما أوصت الدراسة بضرورة البحث عن أسباب ارتفاع نسبة الإصابة بين الذكور ودور الالتهابات المثانية في تطور السرطان.
Critical review
دراسة نقدية: على الرغم من أهمية الدراسة في تسليط الضوء على الأورام المثانية الخبيثة، إلا أنها تفتقر إلى بعض الجوانب الحيوية مثل تحليل العوامل البيئية والوراثية التي قد تكون مؤثرة في ارتفاع نسب الإصابة بين الذكور. كما أن الدراسة لم تتناول بشكل كافٍ دور الفحص الخلوي للبول كأداة تشخيصية مساعدة. بالإضافة إلى ذلك، كان من الممكن تعزيز الدراسة بمزيد من البيانات الإحصائية حول العوامل المسببة للالتهابات المثانية وعلاقتها بتطور السرطان.
Questions related to the research
-
ما هي نسبة الأورام المثانية ذات الدرجة العالية في الدراسة؟
كانت نسبة الأورام المثانية ذات الدرجة العالية 149 من أصل 250 خزعة، أي حوالي 59.6%.
-
كم عدد المرضى الذين تم تشخيصهم في المراحل المبكرة من المرض؟
تم تشخيص 138 مريضاً في المراحل المبكرة من المرض.
-
ما هي التوصيات التي قدمتها الدراسة لتحسين التشخيص والعلاج؟
أوصت الدراسة بضرورة التشخيص المبكر باستخدام وسائل متنوعة، والتحري عن الخلايا الشاذة في البول، والبحث عن أسباب ارتفاع نسبة الإصابة بين الذكور ودور الالتهابات المثانية في تطور السرطان.
-
ما هي الفئة العمرية الأكثر عرضة للإصابة بالأورام المثانية وفقاً للدراسة؟
الفئة العمرية الأكثر عرضة للإصابة بالأورام المثانية هي بين 60 و79 سنة، حيث شكلت 58.47% من الحالات.
References used
KUMAR, V.; ABUL, K.A.; FAUSTO, N. Robbins and Cotran Pathologic Basis of Disease. 7th ed., Elsevier Saunders, International Ed., 2005, 1525
ROSAI, J. Rosai and Ackerman's Surgical Pathology. 8th ed., Mosby, USA & London, 2004, 2977
ADES, T; BROWN, E ;ROSARIO,M.D.ABRAHAMS,N.A.; HUDES, G.R. ; SEXTON, W.J. Bladder Cancer Treatment Guideline For Patients, Version Iii/December 2007, American Cancer Society, National Comprehensive Cancer Network, USA, 2007, 71
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