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The association of defect patterns of basic semen parameters in sperms of infertile men caused by Oligozoospermia

ارتباط أنماط الخلل في المعايير الأساسية للسائل المنوي في نطاف الذكور المصابة بالعقم الناتج عن قلة النطاف

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 Publication date 2012
and research's language is العربية
 Created by Shamra Editor




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Determination of infertility cause and the quality of sperms in semen are the most important factors when we want to choose the suitable method of therapy of assisted reproduction techniques, which has been proven to be the most effective method today in the treatment of many cases of male infertility, and it allows to choose the best sperm for Intracytoplasmic sperm injection technique (ICSI). In our study we tried to find a relationship between one of the semen parameters with the other basic parameters, we studied the concentration motility and morphology of sperms of 23 infertile men with oligozoospermia, and 5 control cases for fertile men.


Artificial intelligence review:
Research summary
تتناول هذه الدراسة العلاقة بين أنماط الخلل في معايير السائل المنوي والنطاف لدى الذكور المصابين بالعقم الناتج عن قلة النطاف. تم تحليل 23 عينة من مرضى يعانون من قلة النطاف و5 عينات شاهدة من أفراد غير عقيمين. تم تقييم تركيز النطاف، حركتها، وشكلها باستخدام معايير منظمة الصحة العالمية، بالإضافة إلى الفحص الخلوي للسائل المنوي لتحديد نسبة التشوهات الشكلية. أظهرت النتائج أن هناك ارتباطاً معنوياً بين الخلل في هذه المعايير، حيث تزداد نسبة النطاف المشوهة وتقل نسبة النطاف ذات الحركة المتطورة كلما قل تركيز النطاف. كما بينت الدراسة وجود علاقة عكسية بين نسبة النطاف المشوهة ونسبة النطاف ذات الحركة المتطورة إلى الأمام. تشير النتائج إلى أن العقم يرتبط بترافق أنماط الخلل في معايير السائل المنوي، مما يستدعي إجراء تحاليل أكثر تعمقاً لتحديد السبب الأساسي للعقم واختيار الطريقة الملائمة للعلاج.
Critical review
تقدم الدراسة معلومات قيمة حول العلاقة بين معايير السائل المنوي والعقم الناتج عن قلة النطاف، إلا أنها تعتمد على عينة صغيرة نسبياً مما قد يؤثر على تعميم النتائج. كما أن الدراسة لم تأخذ في الاعتبار العوامل البيئية والجغرافية بشكل كافٍ، والتي قد تؤثر على معايير السائل المنوي. بالإضافة إلى ذلك، كان من الممكن أن تكون الدراسة أكثر شمولاً إذا تضمنت تحليلات جينية للنطاف لفهم أعمق للخلل الوظيفي. على الرغم من هذه النقاط، فإن الدراسة تسهم بشكل كبير في فهم العلاقة بين معايير السائل المنوي والعقم الذكري وتدعو إلى إجراء المزيد من الأبحاث في هذا المجال.
Questions related to the research
  1. ما هي العلاقة بين تركيز النطاف ونسبة النطاف المشوهة؟

    توجد علاقة عكسية بين تركيز النطاف ونسبة النطاف المشوهة، حيث تزداد نسبة النطاف المشوهة كلما قل تركيز النطاف.

  2. ما هي أهم معايير السائل المنوي التي تم دراستها في هذه البحث؟

    تم دراسة تركيز النطاف، حركتها، وشكلها باستخدام معايير منظمة الصحة العالمية، بالإضافة إلى الفحص الخلوي للسائل المنوي لتحديد نسبة التشوهات الشكلية.

  3. كيف تؤثر قلة النطاف على حركة النطاف؟

    تؤدي قلة النطاف إلى انخفاض نسبة النطاف ذات الحركة المتطورة إلى الأمام، مما يقلل من قدرة النطاف على الإخصاب.

  4. ما هي التوصيات التي خلصت إليها الدراسة؟

    توصي الدراسة بإجراء تحاليل أكثر تعمقاً لتحديد السبب الأساسي للعقم واختيار الطريقة الملائمة للعلاج، مشيرة إلى أهمية تحليل معايير السائل المنوي بشكل شامل لتقييم حالة الخصوبة لدى الذكور.


References used
Jakab A, Sakkas D, Delpiano E, Cayli S, Kovanci E, Ward D, Ravelli A, Huszar G, 2005. Intracytoplasmic sperminjection: a novel selection method for sperm with normal frequency of chromosomal aneuploidies. Fertility and Sterility. 84(6); 1665-1673
Parinaud J, Vieitez G, Moutaffian H, Richoilley G, Milhet P, 1996. Relationships between motility parameters, morphology and acrosomal status of human spermatozoa. Hum Reproduction 11(6); 1240-1243
Karpuz V, Gokturk A, Koyuturk M, 2007. The effects of spermmorphology and motiolity on the outcome of intracytoplasmic sperm injection. Medical Journal. 20(2);92-97
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