يُعدّ اليود الحر (I2) في مطهر البوفيدون اليودي مسؤولاً بشكل مباشر عن فعاليته المطهرة, حيث تزداد هذه الفعالية بشكل يتناسب مع تركيز الشركات اليود الحر. تهدف هذه الدراسة إلى مقارنة بعض محاليل البوفيدون اليودي المسوقة محلياً مع محلول مصنّع من قبل إحدى الأجنبية Betadine® و الذي اعتبر كشكل مرجعي للمقارنة. تم الحصول على العينات التجارية (PVP-I 10%) من ثلاث شركات محلية (A, B, C) مع اختيار طبخة واحدة من كل شركة. شمل البحث مراقبة تركيز اليود الحر, درجة الحموضة بالإضافة إلى تقييم الفعالية المضادة للجراثيم بطريقة الانتشار بالأقراص و سرعة تأثير المطهر على كل من Staphylococcus aureus و Escherichia coli. أبدت محاليل الشركات المحلية قيم pH منخفضة بالمقارنة مع محلول البيتادين الأجنبي, من جهة أخرى أبدت المحاليل التجارية لدى استخلاص اليود الحر منها بالهيبتان احتواءها على تراكيز كافية من اليود الحر مع ظهور أفضلية لإحدى الشركات. ترافق ارتفاع مستوى اليود الحر مع ازدياد في قطر التثبيط و السرعة في الفعل القاتل للجراثيم.
The free iodine (I2) in povidone-iodine (PVP-I) solutions is responsible for its
bactericidal activity, the bactericidal effect is steadily increased with the free iodine
concentration. This study aims to compare some of povidone-iodine solutions common at
the local market with one solution produced by Mundipharma company (Betadine®) which
used as a reference. Commercial samples (PVP-I 10%) were obtained from three local
companies (A, B, C), with one batch from each company. The research included
controlling free iodine concentration, pH and evaluation of bactericidal activity by using
disc diffusion method and rapidity of the bactericidal activity on both Staphylococcus
aureus and Escherichia coli. The local samples solutions showed low pH values compared
with Betadine®, furthermore, all the solutions extracted by heptane showed high levels of
free iodine with a preference for one local company. The high level of free iodine was
accompanied with an increase of inhibition diameter and rapidity of bactericidal effect.
References used
ATEMNKENG, M. A; PLAIZIER-VERCAMMEN, J; SCHUERMANS, A. Comparison of free and bound iodine and iodide species as a function of the dilution of three commercial povidone–iodine formulations and their microbicidal activity. International Journal of Pharmaceutics. 317, 2006, 161–166
BERKELMAN, R. L; HOLLAND, B. W; ANDERSON, R. L. Increased Bactericidal Activity of Dilute Preparations of Povidone-Iodine Solutions. Journal of Clinical Microbiology. 15, 1982, 635-639
BODRUMLU, E; ALACAM, T. Evaluation of Antimicrobial and Antifungal Effects of Iodoform-Integrating Gutta-Percha. Journal of the Canadian Dental Association. 72, 2006, 733-737
The aim of this clinical study compared the use of normal
saline versus (PVP-I) as Irrigating solution during bone
removal on the following edema of The surgical extraction of
the lower third molar impacted.
The concentrations of copper (Cu) and zinc (Zn) in samples of some cereals available at
local markets in Syria weredetermined, after nitric digestion, using Atomic Absorption
Spectrometry. The study showed that the heavy metals were present in all
The concentrations of Copper (Cu) and Zinc (Zn) in samples of some spices
available at some local markets in Syria were determined, after nitric digestion, using
Atomic Absorption Spectrometry. The study showed differences in metal concentrations
Benzoic acid is extensively used in the preservation of food products for maintaining
quality and extending shelf life by inhibiting mould and bacteria growth.
Some previous studies have demonstrated that consumption of excessive amounts of
benzoi
The aim of this study was to control the content of some commercial products containing amino acid (Arginine) available in the local market in addition to other products containing creatine and protein. Three methods were used for quantitative determ