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Erysipelas: Epidemiology and role of lincomycin in the management

الحمرة: وبائيات و دور العلاج باللينكومايسين

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 Publication date 2012
and research's language is العربية
 Created by Shamra Editor




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The aim of this research is to study statistically erysipelas cases and its precipitating factors and also to determine the possibility of considering intramuscular injection of lincomycin as an effective treatment of uncomplicated erysipelas instead of intravenous penicillin G. 60 cases of erysipelas were studied and evaluated. There was no significant relation to age, sex and site of infection. The most affected sites were lower limbs, then face, and upper limbs. The most important risk factors were fungal intertrigo, vascular impairment and finally diabetes mellitus. The response to lincomycin treatment was excellent in 71.71%, intermediate in 23.91% of patients, while there was no response in only 4.34% of cases.


Artificial intelligence review:
Research summary
تستهدف هذه الدراسة التي أجرتها الدكتورة رولا بدور تحليل حالات الحمرة والعوامل المؤهبة لحدوثها، بالإضافة إلى تقييم فعالية العلاج باللينكومايسين كبديل للعلاج الوريدي بالبنسلين في حالات الحمرة غير المختلطة. شملت الدراسة 60 حالة حمرة، ولم تجد علاقة هامة بين الجنس والعمر أو مكان الإصابة. كانت الساق هي الموقع الأكثر إصابة، بينما كانت اليد والوجه الأقل. العوامل المؤهبة الرئيسية كانت المذح الفطري، الاضطراب الوعائي، الرض الموضعي، والسكري. أظهرت النتائج أن العلاج باللينكومايسين كان فعالاً جداً في 71.71% من الحالات، وفعالاً بشكل متوسط في 23.91%، بينما لم يستجب 4.34% من المرضى للعلاج. توصي الدراسة بتبني العلاج باللينكومايسين حقناً عضلياً كبديل للبنسلين الوريدي في حالات الحمرة غير المختلطة، وإجراء دراسات متممة لمتابعة الحالات غير المستجيبة للعلاج.
Critical review
دراسة نقدية: على الرغم من أن الدراسة تقدم بيانات قيمة حول فعالية اللينكومايسين في علاج الحمرة، إلا أنها تفتقر إلى مجموعة مقارنة واضحة مع العلاج التقليدي بالبنسلين. كما أن العينة المدروسة صغيرة نسبياً (60 حالة فقط)، مما قد يؤثر على تعميم النتائج. كان من الأفضل تضمين مجموعة أكبر من المرضى وإجراء دراسة مزدوجة التعمية لضمان دقة النتائج. بالإضافة إلى ذلك، لم يتم التطرق إلى الآثار الجانبية المحتملة للعلاج باللينكومايسين، وهو جانب مهم يجب مراعاته عند تقييم فعالية وسلامة أي علاج جديد.
Questions related to the research
  1. ما هي العوامل المؤهبة الرئيسية لحدوث الحمرة حسب الدراسة؟

    العوامل المؤهبة الرئيسية هي المذح الفطري، الاضطراب الوعائي، الرض الموضعي، والسكري.

  2. ما هي نسبة الاستجابة الممتازة للعلاج باللينكومايسين في الدراسة؟

    كانت نسبة الاستجابة الممتازة للعلاج باللينكومايسين 71.71%.

  3. هل وجدت الدراسة علاقة هامة بين الجنس والعمر أو مكان الإصابة؟

    لم تجد الدراسة علاقة هامة بين الجنس والعمر أو مكان الإصابة.

  4. ما هي التوصيات التي قدمتها الدراسة بناءً على النتائج؟

    توصي الدراسة بتبني العلاج باللينكومايسين حقناً عضلياً كبديل للبنسلين الوريدي في حالات الحمرة غير المختلطة، وإجراء دراسات متممة لمتابعة الحالات غير المستجيبة للعلاج.


References used
BOLOGNIA, J;JORRIZZO,J;RAPINI,R. Dermatology.2 °.ed, Mosby,Elsevier, Spain,2008:2391
DUBERTRET,L.;.ARACTANGI,S.; BACHELEZ,H.; BODEMER,C.;CHOSIDOW,O.; CRIBIER,B.; JOLY,P. Therapeutique dermatologique.2 .ed, Medecine-sciences, Flammarion, Paris, 2001:128
DUPUY,A;BENCHIKHI,H;ROUJEAU,JC .Risk factors for erysipelas of the leg(cellulitis):case control study.Br Med J,1999,318:1591-1594
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