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Studying the Relationship between Atrial Fibrillation and Left Atrial Enlargement

دراسة العلاقة بين الرجفان الأذيني و توسع الأذينة اليسرى

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 Publication date 2013
  fields Medicine
and research's language is العربية
 Created by Shamra Editor




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A study was conducted in Al-Assad University Hospital in Lattakia during the period February 2012 and February 2013 the study included a random sample of 97 patients (males and females) divided into three groups: the first group consisted of 16 patients with left atrial enlargement with no atrial fibrillation, the second group included 70 patients who had left atrial enlargement with atrial fibrillation, and the third group of 11 patients had atrial fibrillation with no left atrial enlargement. In the study the ECHO Doppler was used for measuring left atrial volume index (LAVI) through the Simpson method, this is in order to assess the role and relationship with the occurrence of atrial fibrillation. It was found out that three patients out of (16) from the first group about 18.75% developed an atrial fibrillation after one year of follow-up, which means that the left atrial enlargement gave a predication of the occurrence of atrial fibrillation. The continuation of atrial fibrillation was also noticed together with its lifetime with an increase in the size of left atrial after one year of following-up the patients of the second group. 3 out of (11) patients from the third group had an increase in the left atrial volume index at the end of the study 45.45% (P<0.001), Accordingly the atrial fibrillation could cause left atrial enlargement.Even though the left atrial enlargement may cause atrial fibrillation and vice versa according to thisstudy, the study shows the possibilities of existence of other variable factors related to atrial fibrillation whichplay a role in the occurrence.


Artificial intelligence review:
Research summary
تُعنى هذه الدراسة التي أُجريت في مشفى الأسد الجامعي باللاذقية بين فبراير 2012 وفبراير 2013 بفحص العلاقة بين الرجفان الأذيني وتوسع الأذينة اليسرى. شملت الدراسة 97 مريضًا تم تقسيمهم إلى ثلاث مجموعات: الأولى تضم 16 مريضًا لديهم توسع أذينة يسرى بدون رجفان أذيني، الثانية تضم 70 مريضًا لديهم توسع أذينة يسرى مع رجفان أذيني، والثالثة تضم 11 مريضًا لديهم رجفان أذيني بدون توسع أذينة يسرى. تم قياس حجم الأذينة اليسرى باستخدام الايكو دوبلر القلبي بطريقة سيمبسون لتحديد العلاقة بين توسع الأذينة وحدوث الرجفان الأذيني. أظهرت النتائج أن توسع الأذينة اليسرى يمكن أن يكون مؤشرًا لحدوث الرجفان الأذيني، وأن الرجفان الأذيني يمكن أن يؤدي إلى زيادة حجم الأذينة اليسرى. كما أظهرت الدراسة احتمالية وجود عوامل أخرى مؤهبة تلعب دورًا في حدوث الرجفان الأذيني.
Critical review
دراسة نقدية: تُعد هذه الدراسة خطوة مهمة في فهم العلاقة بين الرجفان الأذيني وتوسع الأذينة اليسرى، إلا أنها لم تتناول بعض العوامل المؤثرة الأخرى بشكل كافٍ، مثل تأثير العوامل الوراثية والبيئية. كما أن استخدام عينة صغيرة نسبيًا قد يؤثر على تعميم النتائج. بالإضافة إلى ذلك، كان من الممكن تحسين الدراسة من خلال متابعة المرضى لفترة أطول واستخدام تقنيات تصوير أكثر تطورًا مثل التصوير بالرنين المغناطيسي (MRI) للحصول على نتائج أكثر دقة.
Questions related to the research
  1. ما هي العلاقة بين توسع الأذينة اليسرى والرجفان الأذيني؟

    توسع الأذينة اليسرى يمكن أن يكون مؤشرًا لحدوث الرجفان الأذيني، والعكس بالعكس، حيث يمكن أن يؤدي الرجفان الأذيني إلى زيادة حجم الأذينة اليسرى.

  2. ما هي الطريقة المستخدمة لقياس حجم الأذينة اليسرى في هذه الدراسة؟

    تم استخدام الايكو دوبلر القلبي بطريقة سيمبسون لقياس حجم الأذينة اليسرى.

  3. ما هي نسبة المرضى الذين تطور لديهم رجفان أذيني بعد سنة من المتابعة في المجموعة الأولى؟

    حوالي 18.75% من المرضى في المجموعة الأولى تطور لديهم رجفان أذيني بعد سنة من المتابعة.

  4. هل هناك عوامل أخرى مؤهبة لحدوث الرجفان الأذيني غير توسع الأذينة اليسرى؟

    نعم، أظهرت الدراسة احتمالية وجود عوامل أخرى مؤهبة تلعب دورًا في حدوث الرجفان الأذيني.


References used
Abhayaratna et al. Left Atrial Size. JACC.2006,Vol.47, No.12 , 34-42
Casaclaug- Verzosa et al. Structural and Functional Remodeling of the Left Atrial Size . 2008JACC, Vol.51 , No.7, 230-241
David Couen et al. Alcohol Consumption and Risk of AF. JACC. 2011 Vol.57 ,No.25, 63-72
Emad.F.Aziz et al. Right Ventricular Dysfunctions is a Strong Predictor of Devoloping AF in Acutely Decompensated Heart Failure Patients. Journal of Cardiac Failure. 2010 , Vol.16 ,No.10, 58-67
Gatia et al. Different Patterns of Atrial Activation in Idiopathic AF Simultaneous Multisite. Atrial Mapping in Patients with Paroxysmal and Chronic AF. JACC. 2001Vol.17, No.2, 157-178
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