Uric acid (UA) has a role in pathogenesis of several metabolic abnormalities including insulin resistance (IR) and their related disorders. The aim of this report is to review the available evidences that reveal the association between UA, IR and rel
ated disorders via both noninsulin and insulin-based IR indices.
METHODS: The published literature was surveyed using Google Scholar and PubMed entering the terms Obesity, UA, IR, Metabolic Syndrome (MetS), Gestational Diabetes (GDM), Polycystic Ovarian Syndrome (PCOS).
RESULTS: UA had substantial positive relationships with IR, as well as obesity, MetS, DM, GDM, and PCOS. Evidently UA with a role in oxidative stress, endothelial dysfunction and induction of inflammation may cause IR in totality, the major factor in development of MetS and related diseases. Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), insulin based IR index, correlated positively with UA. Moreover, specifically triglyceride to high density lipoprotein cholesterol ratio (TG/HDL-C), visceral adiposity index (VAI), lipid accumulation product (LAP), triglyceride to fasting glucose (TyG) index are noninsulin-based IR indices of positive correlations with UA. MetS score for IR (MetS-IR), a non-insulin based IR index, had significantly proportional correlations with MetS components as well as UA level. UA to HDL-cholesterol ratio (UHR) was a pronounced statistical predictor of MetS and diabetes control. UA positively associated with hyperinsulinemia and IR in prediabetes.
CONCLUSION: Succinctly UA can be an emerging biochemistry marker of predictive role in IR, MetS and related anomalies. More hyperuricemia related studies are warranted to be oriented from being correlational to mechanistic
Ploycystic ovary syndrome is one of the most common endocrine disorders in women, affecting 6-10% of reproductive-aged women.
The dermatological manifestations of hyperparathyroidism, hirsutism, acne vulgaris, androgenic alopecia and acanthosis nigricans are among the cardinal manifestations of PCOS
Introduction: Liver surgery is a relatively recent and relatively major complex surgery, due
to the anatomical and histological specialty of the liver.
Objective of the research: To evaluate the results of the cases of non traumatic liver
resectio
n from November 2010 until the end of June 2017
The study included 23 patients with 61% of females and average age of 46.8 years. 30.43%
of the cases were benign lesions, while malignant lesions constituted 65.12% of all
patients. The highest percentage of lesions was of colorectal tumors with 66.66% of all
metastatic patients and 43.47% of all patients. Whereas hepatocellular carcinoma HCC
were only in 4.35% of all patients
The most common surgical procedure was segment resection. The left or right hemi
hepatectomy was in two cases, 8.7%
None of the patients had any complications which requiring a reoperation. Biliary fistula
occurred in two cases, one of which was administered conservatively, the other requiring
ERCP.
The effect of adding two organic acids(formic acid, acetic acid). with broiler drink
water was tested to evaluate their efficacy on the their performance and health Groups
treatment consumed amounts of feed that are greater than the control but for
The results in
the six trials showed superiority of the feed conversion ratio and the final weight of broiler
in the two groups that was added complex to its drink water, compared to the control with
significant differences at 0.05.
There was no significant difference between the replicates of each trial on its own
while the results of laboratory parasite testing of samples litter showed that the number of
oocysts in the litter was the lowest in the treatment groups with significant differences
compared to the control. It was noted that the number of oocysts in litter increased until a
certain age and then began to decline.
The results also showed reduced mortality in all trials with treatment and there were
no significant differences in treatment groups compared to the control.
The research was conducted on 60 patients, checking in the Department of Obstetrics
and Gynecology at the Assad University Hospital in Latakia, complaining of infertility(an
initial or secondary) between2011-2013
A satisfactory detailed story of t
he couple was taken with extra focus on the clinical
symptoms of polycysticovary of the wife (obesity, hirsutism, irregular menstruation,
infertility) and overlooking other feminine or masculine causes of infertility. In addition to
the calibration of Fsh, Lh, free testosterone, and ultrasound imaging of the uterus and
ovaries,
a perforation was performed on the ovaries by laparoscopic surgery. Patients were
checked for a year. This check up showed healthy pregnancy in 27 patients by 45%, but
this didn't work for 31 patients by 51.66%. In addition, 2 cases of abortion3.33% were
reported. . The study showed that age, duration of infertility and the rate of LH had an
effect on the success of the laparoscopic ovarian drilling process with patients of
Polycystic ovary.
The aim of this study is to determine the prevalence of
pulmonary hydatid cysts, determine the best approach of surgical
treatment, and determine the outcomes of hydatid disease in, isolated or
coexisting pulmonary or extrapulmonary hydatidosis.
The study was conducted at the Department of
Thoracic Surgery at Damascus University, between January 1993 and
December 2002, on 206 patients
This study was performed in children’s hospital of Damascus University which
included all cases of hydatid cysts admitted to the hospital between 1/1/1994 and
1/9/1996.
The number of cases totaled 47 which accounted for 1.4 to 2.4 per 1000
admission in different years.
