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Acute Kidney injury, after coronary angiography incidence , complication Al- Assad University Hospital Population-Based Study

الأذية الكلوية الحادة التالية للقثطرة القلبية : الحدوث و الإختلاطات دراسة عينة من مرضى مشفى الأسد الجامعي

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 Publication date 2016
  fields Medicine
and research's language is العربية
 Created by Shamra Editor




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Radiocontrast-induced nephropathy, is becoming increasingly common cause of Acute kidney injury (AKI).The aim of the present prospective study was to find out the incidence and outcome of CIN in patients undergoing coronary angiography. Over a one year period [2014]. At al-Assad university Hospital-Syria. 54 patients , satisfied the criteria for entering into the study.Median age was 56 yr All were followed for development of acute renal failure. The incidence was found to be 22.2 % .12 developed some evidence of acute renal failure .4 required dialysis acutely. There were 2 deaths. and pre existing renal impairment is one of the risk factors for developing contrast induced nephropathy. Serum Creatinine should be measured routinely in all patients who are scheduled form coronary angiography.


Artificial intelligence review:
Research summary
تتناول هذه الدراسة التي أجراها د. عنان لايقة في مشفى الأسد الجامعي في سوريا خلال عام 2014، موضوع الأذية الكلوية الحادة الناتجة عن استخدام المادة الظليلة بعد إجراء القسطرة القلبية. هدفت الدراسة إلى تحديد نسبة حدوث هذه الأذية واختلاطاتها بين المرضى الذين خضعوا للقسطرة القلبية. شملت الدراسة 54 مريضاً بمتوسط أعمار 56 سنة، وتم قياس مستويات كرياتينين المصل قبل وبعد القسطرة. أظهرت النتائج أن نسبة حدوث الأذية الكلوية بلغت 22.2%، حيث طور 12 مريضاً شكلاً من القصور الكلوي، واحتاج 4 مرضى للتحال الدموي، وتوفي مريضان. يعتبر القصور الكلوي السابق عامل خطورة رئيسي لتطور الأذية الكلوية بعد استخدام المادة الظليلة. توصي الدراسة بضرورة معايرة كرياتينين المصل بشكل روتيني قبل وبعد القسطرة القلبية لتقليل مخاطر الأذية الكلوية.
Critical review
تعتبر هذه الدراسة مهمة لأنها تسلط الضوء على مشكلة صحية خطيرة تتعلق باستخدام المواد الظليلة في الإجراءات القلبية. ومع ذلك، هناك بعض النقاط التي يمكن تحسينها. أولاً، حجم العينة الصغيرة (54 مريضاً) قد لا يكون كافياً لتعميم النتائج على جميع المرضى. ثانياً، لم تتناول الدراسة بشكل كافٍ العوامل الأخرى التي قد تؤثر على حدوث الأذية الكلوية مثل الأدوية الأخرى المستخدمة أو الحالات المرضية المصاحبة. ثالثاً، كان من الأفضل تضمين فترة متابعة أطول لتحديد التأثيرات الطويلة الأمد للأذية الكلوية. وأخيراً، يمكن أن تكون هناك حاجة لمزيد من الدراسات التي تتناول استراتيجيات الوقاية والعلاج بشكل أكثر تفصيلاً.
Questions related to the research
  1. ما هي نسبة حدوث الأذية الكلوية الحادة بعد القسطرة القلبية وفقاً للدراسة؟

    بلغت نسبة حدوث الأذية الكلوية الحادة بعد القسطرة القلبية 22.2% من مجموع المرضى المشاركين في الدراسة.

  2. ما هي العوامل الرئيسية التي تزيد من خطر حدوث الأذية الكلوية الحادة بعد استخدام المادة الظليلة؟

    العوامل الرئيسية تشمل القصور الكلوي السابق، التقدم في العمر، والداء السكري.

  3. ما هي التوصيات التي قدمتها الدراسة لتقليل مخاطر الأذية الكلوية الحادة؟

    توصي الدراسة بضرورة معايرة كرياتينين المصل بشكل روتيني قبل وبعد القسطرة القلبية، وتحديد عوامل الخطورة لكل مريض وتطبيق الإجراءات الوقائية اللازمة.

  4. كم عدد المرضى الذين احتاجوا للتحال الدموي نتيجة الأذية الكلوية الحادة؟

    احتاج 4 مرضى للتحال الدموي نتيجة الأذية الكلوية الحادة.


References used
K, Hafeez A, Hou S. Hospital-acquired renal insufficiency. American Nash Journal of Kidney Diseases 2002, 39,930-936
McCullough PA. Contrast-Induced Acute Kidney Injury. Journal of the American College of Cardiology 2008, 51,1419-1428
Riley RF, Don CW, Powell W, Maynard C, Dean LS. Trends in Coronary Revascularization in the United States From 2001 to 2009. Circulation: Cardiovascular Quality and Outcomes 2011, 4,193-197
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