Subscribe to the gold package and get unlimited access to Shamra Academy
Register a new userStudy of the Long Term Stability of Butrylcholinesterase and its Dependence on Sex and Age
دراسة ثبوتية فعالية انزيم كولين استراز مصل الدم و تابعيتها للجنس و العمر
1290
0 1
0
(
0
)
Added by
Damascus University ورقة بحثية
Publication date
2001
fields
Chemistry
and research's language is
العربية
Created by
Shamra Editor
Ask ChatGPT about the research
درست فعالية أنزيم كولين أستراز مصل الدم في ١٦٨ عينة من الذكور ( ٨٠ ) و الإناث ( ٨٨ ) تتراوح أعمارهم بين ١٨-٧٨ عامًا . قيست فعالية الأنزيم في عينة المصل مباشرة و في الأجزاء التي حفظت في الدرجة ٤+ °C و في الدرجة -٢٠°C . أظهرت نتائج البحث تشابهًا في قيم الفعالية في كافة الشروط المدروسة. و تبين لدى دراسة تأثير الجنس على فعالية الأنزيم أنها لدى الذكور أعلى منها لدى الإناث. و قد بدا ذلك واضحًا لدى الذكور الذين تتراوح أعمارهم بين ١٨ و ٥٠ عامًا. كما ازدادت فعالية الأنزيم لدى الإناث اللواتي تزيد أعمارهن عن ال ٥٠ عامًا مقابل الإناث اللواتي أعمارهن أقل، كما لم يظهر أي تغير في فعالية الأنزيم المأخوذ من الذكور .
Specimens of serum from ١٦٨ healthy subjects (٨٠ men and ٨٨ women, ages ١٨ to ٧٨ years)were divided into three groups: fresh, storage at ٤°C, and freezing at-٢٠°C . Periodic essays for the activity of Butrylcholinesterase (BChE,EC. ٣٫١٫١٫٨) were made on each frozen and unfrozen specimen. Serum frozen at-٢٠°C and left at ٤°C gave results similar to those from fresh specimens. Comparison of samples from men and women revealed significantly higher activity in men than in women (P<٠٫٠٠١). Activity was greatest in men aged ١٨-٥٠ years and then declined to slightly lower values. In women the activity was less in those under ٥٠ years old than in those above ٥٠.
References used
Balasubramanian, A.S. and Bhanumathy, C.D. (١٩٩٣): Noncholinergic functions of cholinesterase. FASEB J, ٧, ١٣٥٤-٨
Vellom, D.C., Radic, Z., Li,Y., Pickring, N.A., Camp, S. and Tylor, P. (١٩٩٣): Amino acid residues controlling acetylcholinesterase and butrylcholinesterase specificity. Biochemistry, ٣٢, ١٢-١٧
Whittaker, V.P. (١٩٩٣): The cholinesterase: a discussion of some unanswered questions. Prg. Brain Res., ٣٢, ١٢-٧
rate research
Read More
The study concluded 156 patients having thyroid nodes. All the patients checked up
in Assad university hospital in Lattakia between 2008-2012. The majority of patients
having thyroid nodes were 133 females a 85,26% compared to 23 male patients a 14
,74%.
Most patients are young approximatelyin their forties'. 78,21% of patients complained
about having an enormity in the upper side of their necks. All clinical and Ultrasound
examinations were conducted on all patients. The clinical examination was the answer to
diagnosis. From the other hand the Ultrasound examination was more accurate and
reliable. Fine-Needle Aspiration (FNA) was done for 30 patients and it was directed to 18
patients, but the result was negative for the rest. All tissue samples, which were taken
while surgery, were studied and the result was , most nodes were not tumors, as tumors
were only discovered in 23 patients a 14,74% and the majority of those tumors were
papillary carcinoma.
The study concluded that thyroid node in male patients has a higher chance to be a
tumor by (2:1),after studying the tumors spread according to age and sex factors compared
to the spread of thyroid node according to the same factors. In addition,the study concluded
that the possibility of having thyroid nodesbecomes bigger as one gets older.Ther is no
relation between the size of thyroid node and it's malignancy.
The study aimed to identify the relationship between social
support and quality of life in a sample of teenagers with physical
disabilities in Damascus governorate level, and know of the
differences in their social support and quality of life, acc
ording to two
variables (sex and age). The study sample consisted of 112 students
from physical disabilities Adolescents were selected purposely from
government special education centers, and applied to them two Tools
social support and quality of life, and are prepared by the researcher
after verifying of validity and reliability.
Chronic periodontitis (CP) is an inflammatory disease, characterized by gingivitis,
and affecting tooth supporting tissues, forming periodontal pockets with associated
attachment loss, alveolar bone resorption. It is common in adults, but can also
occur at any
age. The rate of disease progression may be influenced by local, systemic conditions,
and/or environmental factors that alter the normal host response to bacterial plaque, and
affect the susceptibility to disease.It is suggested that periodontitis is partially associated
by genetic factors, that many genes are involved in inflammation susceptibility, mainly
include the vitamin D receptor (VDR) gene that is implicated in bone metabolism and the
host immune response.
80 Syrian subjects were recruited for vitamin D receptor gene polymorphism study,
and allocated in two groups: 50 diagnosed with CP and mean age was (64 ± 0.722) years,
30 matched controls. DNA was isolated from peripheral blood cells, and genotyping was
performed by polymerase chain reaction (PCR) method and restriction fragment length
polymorphism analysis (RFLP) by using FokI enzyme.
By using Chi square test, no significant differences were found between the study
groups in the frequencies of alleles and genotypes at FokI position of VDR gene, age and
sex. These findings suggest that the investigated factors are not associated with periodontal
disease in this studied sample of Syrian population.
This study was conducted to evaluate the effects of butyric acid alone or with
Vitamins in the feed on liver enzymes activity and some minerals in serum.
One hundred (100) 1-day old unsexed commercial Japanese quail chicks were
studied for 42 days
. The Japanese quail chicks were randomly divided into 4
groups as 25 chicks in each. The chicks were fed with starter mash which
contained crude protein24% and metabolizable energy 2850 Kcal / kg up to 42
day of age.
Fractures of the mandibular condyles are frequent in facial traumas and their treatment represents a highly controversial issue in maxillofacial traumatology, functional and surgical treatments being the two principal management modalities for such f
ractures.
The aim of this study is to evaluate the results of functional treatment of mandibular condylar fractures in patients which received this type of treatment.
Eighty-six patients between 6 and 66 years old who were previously treated fuctionally for a fracture of the mandible condyle were recalled for follow up examination with a mean postoperative observation time of 10.4 years. Mandibular function was assessed using the mandibular function impairment questionnaire and patient's complaints were assessed during physical examination. The results showed a significant increase of dysfunction index values with increasing age at the time of trauma. Radiologic abnormalities such as reduced ramus height, deviation of the mandibular midline, and irregular shape of the condyle were observed and seen frequently, but they were not correlated with the severity of dysfunction. Predictors of mandibular function impairment after closed treatment of fractures of the mandibular condyle were: great deviation, reduced mouth opening, women gender, and increased age. The results of this study support the opinion that functional treatment is sufficient in pediatric patients, whereas in older age groups the results of conservative treatment are less sufficient
Log in to be able to interact and post comments
comments
Fetching comments
Sign in to be able to follow your search criteria
