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Thyroid node The relation between (size _ sex _ age ) and malignancy

العقدة الدرقيَّة العلاقة بين ( الجنس _ العمر _ الحجم ) و الخباثة

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 Publication date 2015
and research's language is العربية
 Created by Shamra Editor




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The study concluded 156 patients having thyroid nodes. All the patients checked up in Assad university hospital in Lattakia between 2008-2012. The majority of patients having thyroid nodes were 133 females a 85,26% compared to 23 male patients a 14,74%. Most patients are young approximatelyin their forties'. 78,21% of patients complained about having an enormity in the upper side of their necks. All clinical and Ultrasound examinations were conducted on all patients. The clinical examination was the answer to diagnosis. From the other hand the Ultrasound examination was more accurate and reliable. Fine-Needle Aspiration (FNA) was done for 30 patients and it was directed to 18 patients, but the result was negative for the rest. All tissue samples, which were taken while surgery, were studied and the result was , most nodes were not tumors, as tumors were only discovered in 23 patients a 14,74% and the majority of those tumors were papillary carcinoma. The study concluded that thyroid node in male patients has a higher chance to be a tumor by (2:1),after studying the tumors spread according to age and sex factors compared to the spread of thyroid node according to the same factors. In addition,the study concluded that the possibility of having thyroid nodesbecomes bigger as one gets older.Ther is no relation between the size of thyroid node and it's malignancy.


Artificial intelligence review:
Research summary
تتناول هذه الدراسة العلاقة بين حجم العقدة الدرقية، جنس المريض، وعمره، وخطر تحول العقدة إلى خباثة. شملت الدراسة 156 مريضًا راجعوا قسم الجراحة في مشفى الأسد الجامعي باللاذقية بين عامي 2008 و2012. كانت غالبية المرضى من النساء بنسبة 85.26%، ومعظمهم في العقد الرابع من العمر. كانت الشكوى الرئيسية هي الضخامة في مقدمة العنق بنسبة 78.21%. أظهرت الفحوصات السريرية والإيكوغرافية أن الفحص السريري كان مفتاح التشخيص، لكن الإيكوغرافي كان أكثر دقة. أجريت خزعة بالإبرة الرفيعة لـ 30 مريضًا، وكانت النتيجة إيجابية في 18 حالة فقط. أظهرت الدراسة النسيجية أن معظم العقد كانت حميدة، حيث شخصت الخباثة في 23 مريضًا فقط بنسبة 14.74%. تبين أن العقدة الدرقية لدى الذكور تحمل خطورة أكبر لأن تكون خبيثة بنسبة 2:1، وتزداد نسبة الخباثة مع تقدم العمر، ولم توجد علاقة بين حجم العقدة وخباثتها.
Critical review
دراسة نقدية: تعتبر هذه الدراسة مهمة نظرًا لأنها تسلط الضوء على عوامل الخطر المرتبطة بالخباثة الدرقية. ومع ذلك، هناك بعض النقاط التي يمكن تحسينها. أولاً، كان من الممكن أن تكون الدراسة أكثر شمولية إذا شملت عينة أكبر من المرضى. ثانيًا، لم يتم استخدام تقنيات حديثة مثل الإيكوغرافي الموجه بالإبرة الرفيعة بشكل كافٍ، مما قد يؤثر على دقة النتائج. وأخيرًا، كان من الممكن أن تكون هناك متابعة أطول للمرضى بعد الجراحة لتقييم النتائج على المدى الطويل.
Questions related to the research
  1. ما هي النسبة المئوية للمرضى الذين كانت لديهم عقد درقية خبيثة في هذه الدراسة؟

    كانت نسبة المرضى الذين كانت لديهم عقد درقية خبيثة 14.74%.

  2. ما هو الجنس الأكثر عرضة لتحول العقدة الدرقية إلى خباثة؟

    الذكور كانوا أكثر عرضة لتحول العقدة الدرقية إلى خباثة بنسبة 2:1 مقارنة بالإناث.

  3. هل هناك علاقة بين حجم العقدة الدرقية وخباثتها؟

    لم توجد أي علاقة بين حجم العقدة الدرقية وخباثتها.

  4. ما هي الشكوى الرئيسية لمعظم المرضى في هذه الدراسة؟

    الشكوى الرئيسية لمعظم المرضى كانت الضخامة في مقدمة العنق بنسبة 78.21%.


References used
Nasser M., Kasem F.,Butross M., Ali M., Alloush A., surgical disease for fourth year medical student– 2011-2012
Franklyn , J , E .Diagnosis and management of thyroid nodules. Ann J Surgery 2002, 184 :15-28
Gharib, H et al. AACE/AME medical guidelines for clinical prac-tice for the diagnosis and management of thyroid nodules.Endocr pract 2006;12(1):63-102
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