This study aimed to define the levels of vitamin D3 in postmenopausal women and
their relation with bone mineral density (BMD). The study included 83 women (48-81 year)
who visited the Department of radiology of Al Asad hospital in Lattakia. Bone m
ineral density of
the lumbar spine (L1–L4) and total hip was measured by dual-energy X-ray absorptiometry (DXA).
Blood samples were collected to assay 25(OH)D3 and Ca.
The mean level of 25(OH)D3 was 18.87 ng/ml (6.96 SD) and the prevalence of
vitamin D3 difficiency { 25(OH)D3<20 ng/ml} was 64%. No correlation was found
between BMD and 25(OH)D3 levels [P value>0.05], and no correlation was found between
25(OH)D3 and age or body mass index (IMD). We found a strong correlation between
25(OH)D3 and duration of sun exposure (P value = 0.01). Conclusion: Hypovitaminosis D3
is very common among postmenopausal women. Vitamin D33 status may not be an
important determinant of bone health.
Systemic mastocytosis (SM) is a rare malignant neoplasia,
which can create bone complications. The most frequent of those
is secondary osteoporosis, sometimes responsible for fractures,
especially of the rachis. We report the case of a 53 year-old
woman with 3 non-traumatic lombar fractures, leading to the
diagnosis of SM, after bone marrow trephine biopsy. We describe
the different types of bone involvement in MS, their
physiopathology, their diagnosis and treatment, with help of a
bibliographic review.