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This study aimed to define the levels of vitamin D3 in postmenopausal women and their relation with bone mineral density (BMD). The study included 83 women (48-81 year) who visited the Department of radiology of Al Asad hospital in Lattakia. Bone m ineral density of the lumbar spine (L1–L4) and total hip was measured by dual-energy X-ray absorptiometry (DXA). Blood samples were collected to assay 25(OH)D3 and Ca. The mean level of 25(OH)D3 was 18.87 ng/ml (6.96 SD) and the prevalence of vitamin D3 difficiency { 25(OH)D3<20 ng/ml} was 64%. No correlation was found between BMD and 25(OH)D3 levels [P value>0.05], and no correlation was found between 25(OH)D3 and age or body mass index (IMD). We found a strong correlation between 25(OH)D3 and duration of sun exposure (P value = 0.01). Conclusion: Hypovitaminosis D3 is very common among postmenopausal women. Vitamin D33 status may not be an important determinant of bone health.
Systemic mastocytosis (SM) is a rare malignant neoplasia, which can create bone complications. The most frequent of those is secondary osteoporosis, sometimes responsible for fractures, especially of the rachis. We report the case of a 53 year-old woman with 3 non-traumatic lombar fractures, leading to the diagnosis of SM, after bone marrow trephine biopsy. We describe the different types of bone involvement in MS, their physiopathology, their diagnosis and treatment, with help of a bibliographic review.
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