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Register a new userStudy the Effect of Jews Stone (Fossil Encrinite) on Kidney Stones Treatment in Test Animals
دراسة تأثير حجر اليهود في علاج الحصيات الكلوية عند حيوانات التجربة
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Damascus University ورقة بحثية
Publication date
2012
fields
Pharmacy
and research's language is
العربية
Authors
عبد الناصر عمرين( باحث )
Created by
Shamra Editor
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تقصي إمكانية الإفادة من بعض العوامل المستعملة في الطب الشعبي. استخدمت الأرانب النيوزيلاندية البيضاء حيوانات تجربة، و حجر اليهود علاجاً. و جرى إحداث المرض بحقن 120 ميلي غرام صوديوم غلايوكسيلات صفاقياً . تعد الحصيات الكلوية مشكلة صحية شائعة. يعاني نحو 5% من النساء و 12 % من الرجال على الأقل من الحصيات الكلوية خلال مراحل حياتهم .
The possibility of using some agents used in traditional medicin . Neoziland rabbits was used as experimental animals ; Fossil encrinites was used as a treatment drug ; the disease was induced by injecting 120 mg of sodium glyoxylate intraperitoneally . kidney calculi disease is a common health problem. At least 5% of women and 12% of men during their lives suffer from kidney stones. Lots of herbal drugs and medicinal preparations are used in our country in the treatment of kidney stones.
References used
John R. Asplin, Fredric L. Coe & Murray J. Favus, Nephrolithiasis, In : HARRISON’S Principles of Internal Medicine, 16th ed, Hauser,Longo & Jameson; Pub. McGraw Hill, USA: 1710-1714, 2005
Lyons Ryall R., The Possible Roles of Inhibitors, Promoters, and Macromolecules in the Formation of Calcium Kidney Stones in “Urinary Tract Stones Disease”, Preminger G., Kavanagh J. & Nagaraja Rao P.; Springer-Verlag London Limited , 2011 : 31-60
Roginski , E.E., and Mertz , W. Development and reversibility of urolithiasis in rat by mineral mixtures , J.Nutr., 1974 , 104 : 599-604
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تعد الحصيات الكلوية مشكلة صحية شائعة إذ أن حوالي 5% من النساء و15% من الرجال على الأقل يعانون منها خلال مراحل حياتهم , تستعمل أدوية عشبية ومستحضرات دوائية كثيرة في بلدنا لعلاج هذه الحصيات
This research tends to study clinical manifestation and kinds of kidney illnesses on 50 children visited Al-Assad university hospital in Lattakia from January 1st,2007 to January 1st, 2012 aged between one year to 14 years. The study showed that Heno
ch Schonlein purpura attack both males and females but attack males more (58% males)
(42% females)
This illness increases in spring and winter (40% in spring) ( 36% in winter) .
The study also showed that the illness is systemic disease , mostly attacking skin, joints, gastro intrudes and kidney in which the illness has taken place at 30% in the acute stage and De relapsed stage and the symptoms appeared as varying intensity proteinurea and hematurea
Extra-corporeal shock wave lithotripsy (ESWL) has failed to manage renal
stones > 2cm in diameter. Percutaneous nephrolothotomy lithotripsy (PCNL) has proved to be a very
effective alternative. This study is the first study in Syria about PCNL, ref
lecting our own experience.
To review and to evaluate the results of percutaneous lithotripsy (PCNL) for kidney stones, especially in
regard of indications, steps of the procedures and possible complications.
Purpose: We evaluated the safety of ESWL (Extracorporeal Shockwave Lithotripsy).
Materials and Methods: A total of 300 patients with stones located in the kidney or
the upper ureter were randomly divided into 3 groups, group A—100 who received ESWL
and they do not use anticoagulation drugs and thy do not have problems with kidneys, liver
or pancreas B—100 who received ESWL and they use anticoagulation drugs C—100 who
received ESWL and they have one kidney. Radiologic and laboratory follow up were
performed in the first week by:US –UREA-CR-ALT-AST-AMILAS. Statistical analysis
was performed using the chi square test and Anova test.
Results: The hematomas rate was 10.5%.Rates elevation of urea and cr was
(27%, 5%). Rate elevation of alt–ast was 12%, and for amylase was 6%, without clear
pathology.
Conclusions: ESWL is an easy, noninvasive, safe and active management of the
urinary stones, and we should be care full with some factors, which can increase its
complications and decrease its activity.
Kidney Injury Molecule-1 (KIM-1) is a type 1 transmembrane
glycoprotein. KIM-1 is highly up regulated in proximal tubular
cells following kidney injury. It consists of an extracellular portion,
a novel 6-cysteine immunoglobulin-like domain, 2 N-gl
ycosylation
sites, also contains one transmembrane domain and a short
cytoplasmic domain with a conservative tyrosine phosphorylation
site.
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