Kidney Injury Molecule-1 (KIM-1) is a type 1 transmembrane
glycoprotein. KIM-1 is highly up regulated in proximal tubular
cells following kidney injury. It consists of an extracellular portion,
a novel 6-cysteine immunoglobulin-like domain, 2 N-gl
ycosylation
sites, also contains one transmembrane domain and a short
cytoplasmic domain with a conservative tyrosine phosphorylation
site.
