This study aims to provide GC-FID and GC-MS analyses of the essential oil of dried aerial parts of Ecballium elaterium L. grown in Jordan and examining its cytotoxicity capacity. Methods: Essential oil was obtained by hydrodistillation using Clevenge
r apparatus. MTT assay method was used to investigate the plant's in vitro antiproliferative activity against MCF-7, Caco-2 and Panc-1 cancer cell lines in addition to normal fibroblast cells. Results: E. elaterium hydrodistilled oil yielded thirty one components, accounting for 76.3% of the total oil content. High contents of nonterpenoidal compounds, sesquiterpenes, and monoterpene characterized the volatile fractions with hinesol (17.2%), the principal compound, benzaldehyde (12.3%) and E-β-ionone (7.8%) as the major constituents. E. elaterium ethanolic extract showed good activity against MCF-7 and Caco-2 cells (IC50 values=29.67 μg/mL and 17.64 μg/mL, respectively). Moreover, all extracts were safe on normal human cells. In conclusion: Evaluation of E. elaterium volatile oil has been conducted for the first time in Jordan; also various extracts were tested for the first time against Panc-1 cells. Furthermore, based on the obtained results, ethanol extract of E. elaterium may be advocated as candidate for breast and colorectal cancers management.
The aim of this experiment was to study the protective and
therapeutic effects of Ecballium elaterium juice against
experimental infection with Eimeria stiedae in rabbits. thirty- two
rabbits Divided into four groups (eight rabbits in each group)
:
healthy control group; challenged –Ecballium elaterium –protected
group, which received a daily dose of (45)μl\kg body weight
Ecballium elaterium juice intra-peritoneal for five days before
challenged with E. stiedae; challenged –Ecballium elaterium –
treated group which received a daily dose of (45)μl\kg body weight
Ecballium elaterium juice intra-peritoneal for five days after
challenged with of E .stiedae and infected group. The challenge
dose was 40000 sporulated E. stiedae oocyst per rabbit.
A study was conducted to investigate the protective and therapeutic
effects of Ecballium elaterium juice against experimental infection
with Eimeria stiedae in rabbits. Thirty- two rabbits were divided
into four groups (eight rabbits in each group
) : healthy control group
(HC); challenged – Ecballium elaterium –protected group (CEEP)
which received a daily dose of (45) μl\kg body weight Ecballium
elaterium juice intra-peritoneal for five days before challenged with
E. stiedae ; challenged – Ecballium elaterium –treated group
(CEET) which received a daily dose of (45)μl\kg body weight
Ecballium elaterium juice intra-peritoneal for five days after
challenged with of E .stiedae and infected group (IC).The challenge
dose was 40000 sporulated E. stiedae oocyst per rabbits.
Two species of the Cucurbitaceae were collected and studied during Fep.2013 and June 2014 in Lattakia. As a result of this study, Ecballium elaterium was recorded on the Syrian coast ,while the other was´t.
In this research where they were given an
accurate scientific description The research also included examining the pollens,the result of which was that the pollens were similar in shape of the elliptic, prolate and sometimes globular shape. Trilinear growth holes were proved to exist in both species ,the fact that had made proof the correspondence between them. this Paleonological study is considered to be the first to study such these two species. It involved an anatomical additional study acted upon the above-mentioned. Two species where we examind thin cross section of the root, stem ,leaf neckband and the leaf.
