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Epidemiology and causes of chronin kidney disease and risk factors

دراسة وبائية لأسباب الداء الكلوي المزمن و عوامل الخطورة

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 Publication date 2016
  fields Medicine
and research's language is العربية
 Created by Shamra Editor




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This study was conducted to determine the prevalence and stages of chronic kidney disease and to identify common causes of chronic kidney disease in patients as well as the study of risk factors for the disease. The study included 1314 patients have been admitted to the Department of Internal Medicine at al-Assad University Hospital in Lattakia where they were diagnosed with chronic renal disease patients at 120 of them by 9.1%. The causes of chronic kidney disease were: diabetes 41.7%; hypertension 30%; Glomerulonephritis 11.7%; obstructive uropathy 5%; and Glomerugenetic disease 3.3%; mm3.3%; polycystic kidney d isease3.3% ; idiopathic 1.7%. Chronic kidney disease stages 1; 2; 3; 4; 5; were: 10%; 21.7%; 33.3% 20%; 15% respectively. Risk factors were: advanced age (over 50) 75%; high blood sugar 53.3%; lack of blood albumin 65%; hypertension 38.3%; family history of chronic kidney disease 25%; high triglycerides and cholesterol 11.7% .


Artificial intelligence review:
Research summary
أجريت هذه الدراسة لتحديد معدلات انتشار ومراحل الداء الكلوي المزمن وتحديد الأسباب الشائعة للداء الكلوي المزمن عند المرضى بالإضافة إلى دراسة عوامل الخطورة المتعلقة بالمرض. تضمنت الدراسة 1314 مريضًا تم قبولهم في قسم الأمراض الباطنة في مشفى الأسد الجامعي باللاذقية، حيث تم تشخيص داء كلوي مزمن عند 120 مريضًا منهم بنسبة 9.1%. كانت أسباب الداء الكلوي المزمن متنوعة، حيث كان الداء السكري هو السبب الأكثر شيوعًا بنسبة 41.7%، يليه ارتفاع التوتر الشرياني بنسبة 30%، ثم التهابات الكبب والكلية بنسبة 11.7%. كما تضمنت الأسباب الأخرى اعتلالات بولية انسدادية، أمراض كلوية وراثية، ورم النقي المتعدد، والداء الكلوي عديد الكيسات. أما عوامل الخطورة فكانت تشمل العمر المتقدم (فوق الـ 50) بنسبة 75%، ارتفاع سكر الدم بنسبة 53.3%، نقص ألبومين الدم بنسبة 65%، وارتفاع التوتر الشرياني بنسبة 38.3%. تم تصنيف المرضى إلى خمس مراحل حسب معدل الرشح الكبي، حيث كانت النسب كالتالي: المرحلة الأولى 10%، المرحلة الثانية 21.7%، المرحلة الثالثة 33.3%، المرحلة الرابعة 20%، والمرحلة الخامسة 15%. خلصت الدراسة إلى أن الداء السكري وارتفاع التوتر الشرياني هما الأسباب الأكثر شيوعًا للداء الكلوي المزمن، وأن المرضى كبار السن والذين يعانون من ارتفاع سكر الدم وارتفاع التوتر الشرياني هم الأكثر عرضة لتفاقم المرض. وأوصت الدراسة بضرورة ضبط قيم سكر الدم ومراقبة الضغط الشرياني بشكل مستمر، بالإضافة إلى زيادة الوعي حول الداء الكلوي المزمن وأسبابه وعوامل الخطورة المتعلقة به.
Critical review
دراسة نقدية: على الرغم من أهمية هذه الدراسة في تحديد أسباب وعوامل الخطورة المرتبطة بالداء الكلوي المزمن، إلا أن هناك بعض النقاط التي يمكن تحسينها. أولاً، حجم العينة المدروسة صغير نسبيًا مقارنة بالدراسات العالمية، مما قد يؤثر على دقة النتائج وإمكانية تعميمها. ثانياً، لم تتناول الدراسة بشكل كافٍ العوامل البيئية والاجتماعية التي قد تؤثر على انتشار المرض. ثالثاً، كان من الممكن أن تكون الدراسة أكثر شمولية إذا تضمنت تحليلًا مقارنًا بين مختلف الفئات العمرية والجنسية. وأخيرًا، كان من الأفضل أن تتضمن الدراسة توصيات أكثر تفصيلًا حول استراتيجيات الوقاية والعلاج.
Questions related to the research
  1. ما هي الأسباب الأكثر شيوعًا للداء الكلوي المزمن وفقًا للدراسة؟

    الأسباب الأكثر شيوعًا هي الداء السكري بنسبة 41.7% وارتفاع التوتر الشرياني بنسبة 30%.

  2. ما هي عوامل الخطورة الرئيسية المرتبطة بالداء الكلوي المزمن؟

    عوامل الخطورة الرئيسية تشمل العمر المتقدم (فوق الـ 50) بنسبة 75%، ارتفاع سكر الدم بنسبة 53.3%، نقص ألبومين الدم بنسبة 65%، وارتفاع التوتر الشرياني بنسبة 38.3%.

  3. كيف تم تصنيف مراحل الداء الكلوي المزمن في الدراسة؟

    تم تصنيف مراحل الداء الكلوي المزمن إلى خمس مراحل حسب معدل الرشح الكبي: المرحلة الأولى 10%، المرحلة الثانية 21.7%، المرحلة الثالثة 33.3%، المرحلة الرابعة 20%، والمرحلة الخامسة 15%.

  4. ما هي التوصيات التي قدمتها الدراسة للوقاية من الداء الكلوي المزمن؟

    أوصت الدراسة بضرورة ضبط قيم سكر الدم، مراقبة الضغط الشرياني بشكل مستمر، التقيد بالحمية الغذائية المطلوبة، وتجنب استخدام الأدوية ذات السمية الكلوية أو المواد الظليلة في التصوير الشعاعي.


References used
Terry F ; Epidemiology and causes of chronic renal failure . Medicine 2007 35-8
LINGYU X ; YANXIA L ; XIAOQING F; CHUAIHAI W; ZHANGSHEN R. and XUEBIN Z . Prevalence of chronic kidney disease and associated factors among the Chinese population in Taian,China. Xue et al. BMC Nephrology .2014, 15-205
LARRY J ; JOSEOH L .HARRISON'S Nephrology and Acid-Base Disorders. 17th Edition,McGraw-Hill Medicine ,USA ,2010, 321
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