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سرطان الثدي
1049
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Added by
Tishreen University ورقة بحثية
Publication date
2018
fields
Medicine
and research's language is
العربية
Authors
ناظم ابراهيم رنجوس( باحث )
Created by
Shamra Editor
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- شملت الدراسة 143 مريضة لديهن إصابة بسرطان الثدي و اللواتي راجعن مستشفيي الأسد و تشرين الجامعين باللاذقية في الفترة الواقعة بين عامي 2014-2017 أي أربعة أعوام . - تم توزيع المرضى حسب حجم الكتلة المكتشفة إلى ثلاثة مجموعات و لاحظنا أن النسبة الأكبر هي للكتل أكبر من 2سم و حتى 5سم . - الفئة العمرية الأشيع في الدراسة كانت بين 50- 60 سنة من العمر بنسبة 54.54 % تليها 50-40سنة بنسبة23.77%. - كانت نسبة الاستئصال الجذري المعدل 57.34% من الطرق الجراحية أما الجراحة المحافظة كانت نسبتها %9.79. - السرطانة القنوية في الثدي أكثر شيوعاً من السرطانة الفصيصية بمعدل1/2. - المضاعفات كانت نسبتها %32.86وكانت بسيطة و تم تدبيرها بشكل جيد .
-The study covered 143 famale patients with Breast cancer that have visited AL ASSAD and Tishreen University Hospital of LATAKIA in 2014-2017 (Four years) . -The patients were divided into three groups depending on diameter of the Mass, we found out that the most masses were between (2-5cm) in diameter . -The largest age group in our study was (50-60)years,54.54% then (40-50) years,23.77% . -57.34% of procedures were modified radical mastectomy, while 9.79% were conservative surgeries . -It has been noted that the incidence rate of the invasive Ductal carcinoma to Lobular carcinoma was 2/1 . All complications were simple and properly managed and their rate were 32,86%.
Artificial intelligence review:
Research summary
تتناول الدراسة التي أجراها الدكتور ناظم إبراهيم رنجوس سرطان الثدي من خلال تحليل 143 حالة لمريضات زرن مستشفيي الأسد وتشرين الجامعيين في اللاذقية خلال الفترة من 2014 إلى 2017. تم تقسيم المرضى إلى ثلاث مجموعات بناءً على حجم الكتلة المكتشفة، حيث كانت النسبة الأكبر للكتل بين 2-5 سم. الفئة العمرية الأكثر شيوعاً كانت بين 50-60 سنة بنسبة 54.54%. من بين الإجراءات الجراحية، كانت نسبة الاستئصال الجذري المعدل 57.34%، بينما كانت نسبة الجراحة المحافظة 9.79%. لوحظ أن السرطانة القنوية أكثر شيوعاً من السرطانة الفصيصية بمعدل 2/1. كانت المضاعفات بسيطة وتم تدبيرها بشكل جيد بنسبة 32.86%. الدراسة أكدت على أهمية الكشف المبكر والعلاج المناسب لزيادة فرص الشفاء وتقليل المضاعفات.
Critical review
تعد الدراسة التي قدمها الدكتور ناظم إبراهيم رنجوس ذات قيمة كبيرة في فهم سرطان الثدي في سوريا، خاصةً في منطقة اللاذقية. ومع ذلك، هناك بعض النقاط التي يمكن تحسينها. أولاً، كان من الأفضل تضمين مقارنة أوسع مع دراسات أخرى من مناطق مختلفة لتعزيز النتائج. ثانياً، لم يتم التطرق بشكل كافٍ إلى العوامل البيئية والوراثية التي قد تؤثر على انتشار المرض. ثالثاً، كان من الممكن أن تكون الدراسة أكثر شمولية إذا تضمنت بيانات عن نوعية الحياة بعد العلاج. وأخيراً، كان من المفيد تقديم توصيات أكثر تفصيلاً حول كيفية تحسين الوعي الصحي والكشف المبكر في المجتمع السوري.
Questions related to the research
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ما هي الفئة العمرية الأكثر شيوعاً للإصابة بسرطان الثدي في هذه الدراسة؟
الفئة العمرية الأكثر شيوعاً كانت بين 50-60 سنة بنسبة 54.54%.
-
ما هي نسبة الاستئصال الجذري المعدل بين الإجراءات الجراحية؟
نسبة الاستئصال الجذري المعدل كانت 57.34%.
-
ما هو معدل الإصابة بالسرطانة القنوية مقارنةً بالسرطانة الفصيصية؟
معدل الإصابة بالسرطانة القنوية إلى السرطانة الفصيصية كان 2/1.
-
ما هي نسبة المضاعفات التي تم تسجيلها في الدراسة؟
نسبة المضاعفات كانت 32.86% وكانت بسيطة وتم تدبيرها بشكل جيد.
References used
Baily ₰ love's, Norman.Swillims.Short practice of surgery. 26th edition, 2013,p(1437),(798-822)
Schwartz's, F. Charles Brunicardi . Principles of Surgery . Ninth edition, Houston,Texas,2009, p(1866),(423-469)
Howlader n, noone am, Krapcho m, Miller d, bishop k, kosary cl , yu m,Ruhl J, Tatalovich , Mariotto A, Lewis dr, chen us, Feuer Ej, cornina ka
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A retrospective study included 25 cases with inflammatory breast cancer. The patients were admitted to AL-Assad University Hospital, Lattakia, Syria (average age 55, and range 49-61 years old). The most common clinical signs and symptoms were: erythe
ma 100%, edema 100%, enlarged axillary nodes 100%, Nipple flattened/inverted 96%, warm Breast 92%, Ridges/thickening of breast 84%, Peau d’orange 88%, painful/tender Breast 88%, and Mass 80%. Mammography findings were: an increase in skin thickness 100%, an increased tissue density in the involved breast 100%, and an asymmetric widening of the sub-cutaneous lymphatic vessels 33.33%. 80% of cases were diagnosed as stage IV. All patients received primary neoadjuvant chemotherapy for three cycles. After that a modified radical breast mastectomy and axillary lymph nodes dissection were performed for all patients. The wound edges were closed primarily after dissecting the skin in 76%, for 4 patients 16% a split-thickness skin grafts were performed, and for 2 patients 8% a Latissimus dorsi pedicled myocutaneous flap was performed.
Many studies have been conducted to investigate the relationship between breast cancer and thyroid disorders, and these studies have yielded conflicting results among themselves. Some of these studies have indicated a relationship between breast canc
er and hypothyroidism, while other studies have indicated a relationship between breast cancer and hyperthyroidism, and many studies have not found any relationship. Between breast cancer and thyroid disorders
Background: people with cancer experience great changes in their life as a result of disease, treatment and disease prognosis which affect their quality of life .with the goal of investigating breast cancer patient's quality of life during chemother
apy in Tishreen hospital in Latakia..
Methods: 60 patients were invited to complete the European organization of research and treatment quality of life questionnaire version 3 and breast cancer quality of life module during their early stage of chemotherapy.
Results : the results show that the (73.3%) were under the age of fifty and half of them reported total health status score under (50) which reflects low quality of life in addition to impaired psychological ,social, cognitive and role functioning. Also more than 67% of patient suffered from chemotherapy- related side effects as nausea and vomiting, dyspnea, loss of appetite, insomnia, and fatigue. In addition to variance in quality of life scores according to age, marital status, occupation and level of education without changing of it by educational level. In addition to that the majority of patient had impaired sexual function and upset of hair loss and arm symptoms but with positive and optimistic future.
perspective. No significant differences in quality of life scores were found between urban and rural patients. Conclusion. Health care provider should assess routinely cancer patient quality of life during treatment to ascertain of providing appropriate care with supportive services for all patients
Aim: to assess the expression ofcathepsin B(ctsB; an important protease) in human
breast cancer and correlate that with the tumor grade.
Materials and Methods:Serial sections were obtained from 23 formalin-fixed paraffin
embedded breast cancer tis
sue specimens which were collected from Alasad University
Hospital and a pathological laboratory in Lattakia - Syria. Tissues were stained for
cathepsin B using immunohistochemistry. Tonsil tissues were also included as a positive
control.
Results:Positive cytoplasmic staining of CtsB was observed in both follicular
macrophages and endothelial cells in tonsil sections. In breast cancer tissues, tumor cells,
endothelial cells and stroma stained positive for CtsB. The presence of CtsB in blood
endothelium significantly correlated with the tumor grade (p=0.049).
Conclusion: These results supported the important role of cathepsin B in tumor
progression, particularly in angiogenesis. Future studies should investigate the regulating
mechanisms of cathepsin activities within the tumor environment, and that can be
considered as new tagets for cancer treatment.
In spite of all the advances in health care and medical technology,
provision of quality health care to cancer patients remains one of the
major challenges that health care professionals have to face in the
next years.
this study was conducted to
assess the effect of nursing care on
breast cancer patients quality of life at homes.
by using quazi-experimental design 80 breast cancer patients were
selected (40 experimental group ,40 control group) receiving
chemotherapy recently. Experimental group patients received
supportive psycho-educational interventions consisted of education,
progressive muscle relaxation technique with four supportive range
of motion exercises in addition to emotional support for three
months. While control group patients received routine nursing care
in hospital. The results were assessed for both groups by using
European organization for cancer research and treatment quality of
life questionnaire (EOCRT-QLQ C30) and breast cancer module.
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