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Study of Histological changes in kidneys mice injected by E.coli caused to urinary tract infection

دراسة التغيرات النسيجية في كلى الفئران المحقونة بجراثيم الإيشريكية القولونية المسببة لأخماج المجاري البولية

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 Publication date 2017
and research's language is العربية
 Created by Shamra Editor




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Ninety urin samples were taken from patients suffering from urinary tract infection .the purpose was to isolate and identify Ecoli. After cultural and biochemical diagnosis,[47] isolates had been obtained with [63.5%] for E-coli out of [74] samples that had bacterial growth.

References used
ANDERSON, G,2014 Intracellular bacterial biofilm-like pods , urinary tract infections. Science ,301 ,105–107
ARISOY, M, 2006 Detection of virulence factor of E.coli from children by multiplex polymerase chian reaction, Int. J. Clin. Pract ,60 , 170-173
ASAHRA, T, 2001 Antimicrobiol activity of intravrethrally adminisged robiotic Lactobacillus case in amurine model of E.coil UTI, Antimicrobia. Agents chemother, 45 , 1715-60
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Bacterial pathogens associated with urinary tract infection were studied. The study examined 120 urine samples taken from the middle of the urinary flow of patients with symptoms of urinary tract infection.
The aim of this experiment was to study Histological changes associated with different stages of infection with hepatic coccidiosis induced by Eimeria stiedae in rabbits.
Objective: Evaluate sensitivity and specificity of nitrite test to urine culture(gold standard) for diagnosing urinary tract infection in patients with sickle cell anemia with urinary symptoms and signs. Methods: The study sample included 79 chi ldren aged 2 to 14 years with SCA presenting with fever (temperature >38°C),abdominal pain, urgency, dysuria or increased urinary frequency who referral to the general pediatric clinic and the children's ambulance department in Tishreen University Hospital in Lattakia during( 2016-2017). Midstream urine specimen was collected from children. Samples were subjected to nitrite test, culture and sensitivity. Results : There was significant bacteriuria in 17 (21.5%) children with SCA. A positive test for nitrite was obtained in 12 of the 17(70.5%) children. The nitrite test has a specificity of 95.2% in detecting bacteriuria, a sensitivity of 70.6%, a positive predictive value of 80% and a negative predictive value of 92%. A positive nitrite test was significantly associated with bacteriuria, while a negative test was also significantly associated with an absence of bacteriuria.
Introduction: Urinary tract infections are very common in childhood (especially under the age of 5 years) and because of the large number of complications resulting from it (renal failure – hypertension- kidney scarring) had to be diagnosed and early treatment, although that urine culture is the standard Golden diagnosis, but its results are late to appear, Many studies have indicated an accompanying increase in platelet counts in urinary tract infections, so that platelet counts may be a vital indicator directed to it without asylum to the costly analyzes in its diagnosis. Objective: the objective of the following study is to assess the sensitivity and specificity of the plate count (PLT) in UTI. Methods: The study included 65 Patients (14 males, 51females) They were between (3-6) year with upper urine tract infections were diagnosed through symptoms, urological test, Serum tests, and radiology, who were admitted to the pediatric department at Tishreen University Hospital in Lattakia City. PLT was obtained through a complete CBC blood count (sensitivity and sensitization), and comparison of the ratio Percentage of Thrombocytosis between urine culture with Gram-positive germs and Gram-negative germs. Results: The study showed a good sensitivity=80.39% [75–84] to platelet counts compared to urine culture. it also showed statistically significant paper p-value=0.003 between platelet count and type of pathogen (positive or negative Gram) and the increase was more favorable to positive urine culture. Also showed that the average value of platelets is higher in culture a positive gram 521.9±90.9 x103 platelet/mcl than in gram negative 432.3±73.5 x103 platelet/mcl. Conclusion: higher Platelet numbers are a good analysis or sensitivity for the diagnosis of upper urinary tract infection in children with reliable urinary symptoms to start treatment. So that we get the results of culture urine .and the higher platelet count must be taken gram positive bacteria into account.
تعد الحصيات الكلوية مشكلة صحية شائعة إذ أن حوالي 5% من النساء و15% من الرجال على الأقل يعانون منها خلال مراحل حياتهم , تستعمل أدوية عشبية ومستحضرات دوائية كثيرة في بلدنا لعلاج هذه الحصيات
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