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Termination of the missed abortion in the second trimester by vaginal misoprostol (Cytotec)

انهاء موت محصول الحمل في الثلث المتوسط باستخدام الميسوبروستول ( سايتوتيك ) مهبليا

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 Publication date 2000
and research's language is العربية
 Created by Shamra Editor




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In this study , 103 pregnant women with the diagnosis of missed abortion in the second trimester of pregnancy had been accepted to terminate the pregnancy, by one of two methods : In the first group (53 patients ) we used vaginal Misoprostol (cytotec ) ; in the second group (50 patients) we used the classic method by insertion of Foley catheter followed by induction of uterine contractions by oxytocine . (intravenous infusion ) .

References used
Abramovici D, Goldwasser S, Mabie BC, Mercer BM, Goldwasser R, Sibai BM. A randomized comparison of oral misoprostol versus Foley catheter for induction of labor at term. Am J Obstet Gynecol . 1999 Nov. 181(5 Pt 1): 1108-12
Apgar BS. Current trends in cervical ripening and labor induction Am Fam Physician. 1999 Aug,60(2):418-20
Blanchette HA, Nayak S, Erasmus S. Comparison of the safety and efficacy of intravaginal misoprostol (prosta E1) with those of dinoprostone (prostaglandin E2) for cervical ripening and induction of labor in a community hospital. Am J Obstet Gynecol. 1999 Jun, 180 (6Pt 1) 1551-9
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Objective: To compare the effectiveness of Misoprostol administered intravaginally every 12 versus 6 hours for termination of pregnancy in the first and second trimesters. Methods: Fifty six pregnant patients at 7 – 22 weeks of gestation were ran domized to receive 800 μg (first trimester) and 200 μg either every 12 or every 6 hours for 48 hours. Results: The incidence of abortion within 48 hours after initial dose, in the first trimester was 100% in the two groups, in the second trimester the incidences were 95.5 and 100%. The incidences of abortion by a single dose in the first trimester were 85 and 10% in the 12 and 6 hours groups respectively (P <0.001) The mean abortion intervals 8.3 , 20.2 and 12.4 hours in the 12 and 6 hour group respectively. Side effects were similar in both groups. Conclusion: Misoprostol administered vaginally is effective for termination of first and second trimester pregnancies in non scared uterus. Giving the medication at a shorter interval from 12 to 6 hours appeared to have no significant benefit.
Abortion is the most common complication of early pregnancy, so that should be effectively managed with safe and appropriate procedures. Surgical evacuation of the uterus for management of first trimester abortions usually involves vacuum aspiration or sharp curettage. Objective:To compare the complications of electric vacuum aspiration (EVA) and sharp curettage (D&C) for first trimester abortions, and detect the method that ensure more safety and efficacy. Subjects and methods: The study included one hundred women with incomplete abortion, missed abortion or blighted ovum, gestational age less than 12 weeks whom come to the department of obstetrics and gynecology at Al-Assad university hospital in Lattakia , Syria between 1 July 2013 and 1 July 2014. They were allocated into two groups, group A (n = 50) underwent EVA and group B (n=50) underwent D&C. The procedures were performed using the general anesthesia. We excluded: febrile state, clotting disorders, sever medical and surgical complications, unstable hemodynamic state. Results: Clinical characteristics were similar in the two groups. There were no reports of maternal deaths, cervical laceration, uterine perforation or blood transfusion recorded in the two groups. Blood loss was greater with D&C group than with EVA group (0.001). need an analgesic was greater with D&C group than with EVA group (0.002). Duration of operation and hospitalization was significantly shorter with EVA group than with D&C group. The two groups were similar in success procedure. Conclusion: The efficacy of EVA was the same as that of D&C in successful the procedure, but pain and blood loss were experienced more in the D&C group.
Objectives: Syria is considered to have the highest fertility rate in the world, some of the reasons are due to women themselves and some are due to the health system and its providers. Methods: Our study is a cross sectional study. It included wome n at fertility age between (15-49 years) they were selected using cluster samples at the six Syrian regions. Results: The study showed that about (24%) of sampled women did not use any form of contraception. Husband refusal was the main reason, followed by health issues and fear of side effects, while religious believes and less frequent intercourse were only responsible for a small percentage. The study also showed that about half of the women who underwent induced abortion was because of social reasons and couples wishing not to keep the pregnancy, followed by failure of contraceptive methods mainly oral contraceptive pills. The majority of induced abortions (96%) were done surgically by dilatation and evacuation while medication was only used in a small percentage. Conclusion: Although (95%) of the induced abortions were done by specialists and (96%) of women were satisfied with the service provided, however this procedure was not devoid of major complications although it was in a small percentage but it was serious enough to affect the woman's life and her future fertility.
A study was done about bleeding in first trimester of pregnancy including 816 patients from 3104 pregnant women(26.28 %) . The causes was abortion ( %96.07), ectopic pregnancy (%2.69) and hyditidiform mole (%1.22). In patients with abortion 486 p atients suffered from pain with bleeding(%61.09) and when happeded together the rate of complete abortion elevated . (%78.18) had early abortion whereas(%21.81) had late abortion.The most common high risk factors in patients with abortion were poor and low level of life also the age -35 40 years old(%47.44). The tubal ectopic pregnancy was the most common and the privious pelvic operation is one of the most important high risk factors for ectopic pregnancy. All patients with ectopic pregnancy had amenorrhea with low or no changes in β- HCG levels and (%86.36) had abdominal pain with changes and pain in the cervixs. 16 patients (%72.72) needed surgical therapy.
This study aimed at investigating the effect of a computerized programme on changing alternative concepts in science among second intermediate grade students in the Kingdom of Saudi Arabia in “motion and sound units”. A puroseful sample of (90) st udents was selected and students were randomly assigned to two groups: the experimental group which was taught “motion and sound” by the computerized programme, and the control group which was taught the same two units by the traditional method.
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