طورت طريقة تحليلية سريعة و بسيطة لتعيين مادة هيوسين بوتيل برومايد في الشرابات الفموية السائلة باستخدام الكروماتوغرافيا السائلة عالية الأداء. حللت في هذه العمل العينات مباشرةً دون الحاجة للجوء إلى أي معالجات مسبقة، باستخدام عمود كروماتوغرافي من النوع Intersil ODS-3.
A simple and rapid analytical method for routine quantification of Hyoscine
butyl bromide (scopolamine butyl bromide) in liquid oral formulations by highperformance
liquid chromatography was developed and validated. The oral
solution samples can be directly analyzed by reversed-phase HPLC on Intersil
ODS-3.
References used
Tytgat GN., 2007. Hyoscine butylbromide: a review of its use in the treatment of abdominal cramping and pain; PubMed [Drugs], Volume 67, Issue 9 , pp 1343-1357
Ayman A. Gouda, 2010. Kinetic spectrophotometric determination of Hyoscine butylbromide in pure form and in pharmaceutical formulations; Arabian Journal of Chemistry, Volume 3, Issue 1, Pages 33-38
El-Saharty, Y. S., Metwaly F. H., Refaat M., El-Khateeb S. Z.; 2007. Development of membrane electrodes for the selective determination of hyoscine butylbromide, Talanta, Volume 72, Issue 2, Pages 675-681
A simple and accurate method was developed for the analysis of
carbinoxamine maleate, dextromethorphan hydrobromide and
pseudoephedrine hydrochloride content in pure form and pharmaceutical
preparations using HPLC. Analysis was conducted on a sili
spectrophotometric and chromatographic methods was used for
determination of five water-soluble vitamins, including : Thiamine
HCl (B1), Ascorbic acid (VC), Niacinamide (PP), Cyanocobalamin
(B12), Riboflavin (B2) in this research.
The conditions
The purpose of this article is how to determine simultaneously the content of
some Anti-Inflammatory (NSAIDS):, Ketoprofen, Flurbiprofen, Orphenadrine
Citrate (Muscle relaxant( and Clopidogrel Bisulfate (Anti-thrombocytopenia( in
pure and pharmace
The present study describes a simple stability-indicating reversed-phase HPLC assay
for pentoxifylline in its pharmaceutical dosage forms. Separation of the drug and the
degradation products، under stress conditions was successfully achieved on a C
The possibility to develop a High-Performance Liquid
Chromatographic method was studied for simultaneous
determination of: Cu(II), Ni(II), Co(II), Hg(II) by using DTC as
reagent. The diethyldithiocorbamate Reagent was studied by
spectrophotometric Method, Unique Ionisation Constant was
determined and its value.