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Register a new userMeasuring Adiponect in Levels for Nominated Cardiac Catheterization Patients
قياس مستويات الأديبونكتين عند المرضى المرشحين للقثطره القلبية
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أجريت هذه الدراسة لإثبات دور الأديبونكتين المضاد للتصلب العصيدي، تناولت الدراسة 54 مريض من مراجعي مشفى الأسد والمرشحين لإجراء القثطرة القلبية, 02 شخصاً اعتبروا عينة شاهد. تم قياس تركيز الأديبونكتين وتركيز hs-CRP عند المرضى والشاهد و مقارنتها مع تركيز الأديبونكتين. كما أجريت لهؤلاء المرضى قثطره قلبيه, وصنفت نتيجة القثطرة إلى خفيفة, متوسطة وشديدة وفق مشعر SYNTAX SCORE. كانت النتيجة أن تركيز الأديبونكتين كان أعلى عند المرضى ذوي الإصابة الخفيفة (23.86 مكغ/مل) منه عند ذوي الإصابة المتوسطة والشديدة (13.62مكغ/مل) , (P=0.001<0.05)، وكان متوسط تركيزه المصلي عند الشاهد (16.7مكغ/مل). كما لم يلاحظ وجود أهميه إحصائية للعلاقة بين تركيز hs-CRP وتركيز الأديبونكتين, لكن كان هناك أهميه إحصائية للفرق بين متوسط تركيزhs-CRP عند عينة المرضى (7.1 مغ/ل ) وعينة الشاهد (2.7 مغ/ل). (P=0.003 <0.05).
This study tries to assess the potential anti-atherosclerotic role of adiponectin. It includes 54 patients at Al-Assad University Hospital in Lattakia, who are candidates for catheterization, and control group of 25 individuals. Serum adiponectin levels have been measured in both groups, and levels of hs-CRP have been also measured in both groups and compared with adiponectin levels. Catheterization has been done to the patients group and the results of angiography are categorized to mild, moderate, and severe coronary artery disease (CAD) according to the SYNTAX SCORE The study concludes that serum adiponectin levels are higher in patients with mild CAD(23.86 μg/ml) compared to patients with moderate to severe CAD (13.62 μg/ml);(p=0.001<0.05). The average serum adiponectin levels in control group was (17.1μg/ml). There was no statistically significant of the relation between the concentration of hs-CRP and the concentration of adiponectin .However, there was a statistically significant difference between the average concentration of hs-CRP in the patients group (7.1 mg/l) and the control group (2.7 mg/l); (P=0.003<0.05).
References used
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Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K,et al. The fatderived hormone adiponectin reverses insulinresistance associated with both lipoatrophy and obesity. Nat Med2001;7:941-6
Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med2001;7:947-53
Yamauchi T, Kamon J, Minokoshi Y, Ito Y, Waki H, Uchida S, et al.Adiponectin stimulates glucose utilization and fatty-acid oxidation byactivating AMPactivated protein kinase. Nat Med 2002;8:1288- 95
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mechanisms for the development of cancer are still unknown.
The main aim of the study was to determine the frequency of coronary angiography
complications with or without percutaneous coronary intervention (PCI) by the TR access
compared with the TF access of patients undergoing coronary angiography (CAG).
The
study included 640 patients undergoing CAG with or without (PCI) in AL-ASSAD
university Hospital in Lattakiabetween 1 December 2013 and 31 December 2014 .A total
of 106 CAG (22.8% of all CAG) and 12 CAP (6.7% of all coronary angioplasties) were
performed via a TR approach , 357 CAG (77.2% of all CAG) and 165 CAP (93.3% of all
coronary angioplasties) were performed via a TF approach ,Vascular access site
complications were significantly lower in the TR group than in the TF group.
Background: primary percutaneous coronary intervention PCI is the treatment of
choice in civilized countries for acute myocardial infarction, the aim of the treatment here
is the revascularization as soon as possible. Patients and methods: it is re
trospective study
of 133 patients of acute MI have been divided into two subgroups. The first subgroup has
been treated with streptokinase infusion, and the other subgroup has beet treated by PCI.
We monitored the patients within hospitalization , reinfarction, mortality, cardiogenic
shock, heart failure, also we recorded the time needed to apply the method of treatment and
Timi score by diagnostic cardiac catheterization after applying the treatment.
Aim of study: to compare between streptokinase and PCI in our hospitals to know
which way is better in which we can give the best medical care for this critical patients.
Results: 63 patients undergo to pci and 70 patients undergo to streptokinase therapy.
Streptokinase group had higher rates in mortality for noncardiac reasons 100%,
cardiogenic shock 60% , reinfarction 81%, mortality for cardiac reasons 80%, while it was
faster in applying the treatment and equal to pci in timi score. While pci group has higher
rated in hospitalization for cardiac reasons 70% and in cases that has new congestive heart
failure 63%, and nearly equal to streptokinase group in timi score.
Conclusion: pci was better in mortality and cardiogenic shock and reinfarction than
streptokinase but it was worse in hospitalization for cardiac reasons and congestive heart
failure cases . pci was too late than streptokinase in applying the treatment . we notice that
the two methods of treatment was nearly equal in timi score.
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source and target language in terms of a neural language model's perplexity over Part of Speech (PoS) sequences. Our primary focus is on register diversification vs. convergence, reflected in the use of constructions eliciting a higher vs. lower perplexity score. Our results show that, against our expectations, professional translations elicit higher perplexity scores from a target language model than students' translations. An analysis of the distribution of PoS patterns across registers shows that this apparent paradox is the effect of higher stylistic diversification and register sensitivity in professional translations. Our results contribute to the understanding of human translationese and shed light on the variation in texts generated by different translators, which is valuable for translation studies, multilingual language processing, and machine translation.
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therapeutic concentrations in target tissues of the cardiac muscle. Anti-arrhythmic drugs concentrations
should be high enough to reach the steady- sta
te for the chronic arrhythmia patients, this could be fatal
due to drug accumulation in the cardiac and body tissues. The most important side effect of all kind of
anti-arrhythmic drugs is the capability to initiate different types of cardiac arrhythmia formations in the
treated individuals. The aim of this study is to prove the effectiveness of delivering an anti-arrhythmic
drug, directly to target tissues of the cardiac muscle by using the Iontophoresis concept, in order to
minimize the side effects in cardiac and body tissues and optimize the benefits of anti-arrhythmic drugs
in target tissues. The results from series of experimental procedures proved that very-low iontophoretic
current's values ranges allow feasible and effective passage of anti-arrhythmic drug's ionized particles
into cardiac tissues, and in the same time they were safe on the innervation of autonomic nervous system
fibers in the cardiac muscle. This study focused on relationships among the different parameters which
control the Iontophoresis procedures.
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