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Treatment of acute myocardial infarction by cardiac catheterization and comparing it with fibrinolytic therapy with streptokinase

علاج احتشاء العضلة القلبية الحاد عبر القثطرة القلبية و مقارنتها بحال الخثرة الستربتوكيناز

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 Publication date 2017
and research's language is العربية
 Created by Shamra Editor




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Background: primary percutaneous coronary intervention PCI is the treatment of choice in civilized countries for acute myocardial infarction, the aim of the treatment here is the revascularization as soon as possible. Patients and methods: it is retrospective study of 133 patients of acute MI have been divided into two subgroups. The first subgroup has been treated with streptokinase infusion, and the other subgroup has beet treated by PCI. We monitored the patients within hospitalization , reinfarction, mortality, cardiogenic shock, heart failure, also we recorded the time needed to apply the method of treatment and Timi score by diagnostic cardiac catheterization after applying the treatment. Aim of study: to compare between streptokinase and PCI in our hospitals to know which way is better in which we can give the best medical care for this critical patients. Results: 63 patients undergo to pci and 70 patients undergo to streptokinase therapy. Streptokinase group had higher rates in mortality for noncardiac reasons 100%, cardiogenic shock 60% , reinfarction 81%, mortality for cardiac reasons 80%, while it was faster in applying the treatment and equal to pci in timi score. While pci group has higher rated in hospitalization for cardiac reasons 70% and in cases that has new congestive heart failure 63%, and nearly equal to streptokinase group in timi score. Conclusion: pci was better in mortality and cardiogenic shock and reinfarction than streptokinase but it was worse in hospitalization for cardiac reasons and congestive heart failure cases . pci was too late than streptokinase in applying the treatment . we notice that the two methods of treatment was nearly equal in timi score.

References used
LEONARD S. LILLY, MD. Pathophysiology of Heart Disease. s.l. : Lippincott Williams & Wilkins, a Wolters Kluwer business, 2011, pp. 8-9-10-11-12
PATHOPHISOLOGY OF HEART DISEASE. S.L. : Lippincott Williams & Wilkins, a Wolters Kluwer business, 2011, pp. 162-163-164-165-166-167-168-169-170- 171-172-173-174-174-175-176
HYPERLINK "file:///C:\\Users\\ghazwan\\Desktop\\UpToDate-1\\contents\\ mobipreview. htm?36/31/37369/abstract/4" ANDERSON JL, KARAGOUNIS LA, CALIFF RM. Metaanalysis of five reported studies on the relation of early coronary patency grades with mortality and outcomes after acute myocardial infarction. Am J Cardiol 1996; 78:1
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Introduction: The cardiogenic chock is the most cause of death following to acute myocardial infarction (IMA) ,it occurs( 10%) in patients who are hospitalized in soins intensive for acute myocardial infarction Lot of patient with acute myocardial infarction develops cardiogenic shock after arriver to hospital The cardiogenic chock with STEMI (7.5%) is more than its with NSTEMI (2.5%) The cardiogenic chock occurs in diabetic patients two field more than non diabetic patient may the prognosis is the same Study methods: our study is retrospective has been done in soins intensive in University Alassad hospital in Lattaquie It includes all patients admitted for acute myocardial infarction pendant the period from January 2014 to January 2016 Results :The percentage of cardiogenic shock in our study is( 12%) .(29.4%)of them are arrived to hospital with cardiogenic shock while( 70.6%) developed cardiogenic shock pendant their hospitalization The responsible pathologies of cardiogenic shock were as following: left ventricular dysfunction (58%) isolated right ventricular shock( 24% ) acute mitral valve insufficiency (11%),septa l interventricular rupture(5%)
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