This research tries to the rate of arrhythmia manifested during the first (48) hours of heart infarction and define its nature as well as its relationship with heart infarction in regard to patients subjected to anti-coagulation (streptokinase) ther
apy and patients who were not subjected to it. Moreover, it also aims to detect the relationship between arrhythmia and the death rates of the patients during their stay in the Heart Intensive Care Unit.
The study started in October 2012 and lasted twelve months, up to October 2013.
The sample of study here consisted of (187) patients hospitalized in the Heart Intensive Care Unit having acute myocardial infarction. The sample included (142) males (76 % of the sample) and (45) females (24%). The research reached the following findings:
A hundred and seven of the patients monitored in the study were smokers; and smoking was the most important risk factor causing myocardial infarction.
Ventricular extra systole were the most common symptoms of acute myocardiac infarction arrhythmia during the first (48) hours of hospitalization reaching (79%). The second was increased auto ventricular rhythms rating (43 %).
High rates of dangerous arrhythmia like (VT) and (VF) rating (9%) in patients who were not subjected to streptokinase (anti-coagulation) compared with those subjected to it (4. 5%), and (3.8) respectively.
Decreased (EF) increased the possibility of life-threatening ventricular arrhythmia like (VT).
Diabetes did not increase the dangers of arrhythmia monitored in this research
The efficiency of anti-arrhythmic drugs could be weak if they were administrated in insufficient
therapeutic concentrations in target tissues of the cardiac muscle. Anti-arrhythmic drugs concentrations
should be high enough to reach the steady- sta
te for the chronic arrhythmia patients, this could be fatal
due to drug accumulation in the cardiac and body tissues. The most important side effect of all kind of
anti-arrhythmic drugs is the capability to initiate different types of cardiac arrhythmia formations in the
treated individuals. The aim of this study is to prove the effectiveness of delivering an anti-arrhythmic
drug, directly to target tissues of the cardiac muscle by using the Iontophoresis concept, in order to
minimize the side effects in cardiac and body tissues and optimize the benefits of anti-arrhythmic drugs
in target tissues. The results from series of experimental procedures proved that very-low iontophoretic
current's values ranges allow feasible and effective passage of anti-arrhythmic drug's ionized particles
into cardiac tissues, and in the same time they were safe on the innervation of autonomic nervous system
fibers in the cardiac muscle. This study focused on relationships among the different parameters which
control the Iontophoresis procedures.
