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The role of Interleukin-1 genes in the association between chronic periodontitis and atherosclerosis has been under debate. The purpose of this study is to compare the existence of interleukin1 genes polymorphism in the chronic periodontitis subjects with and without atherosclerosis.
Many methods are used to treat Periodontitis such as scaling and root planing (SRP) with hand instruments, Sonic and Ultrasonic instruments. Recently, lasers are used in periodontal. The aim of the study is to compare the Efficiency of Er:YAG Laser Combined with Scaling and Root Planing in Chronic Periodontitis Treatment.
The study aimed to Compare the effect of combination Platelet Rich Plasma with bovine derived xenograft and bovine derived xenograft alone in treatment of human class II furcation defects in mandibular molars. Twenty systemically healthy patients, aged 32 to 58 years with chronic periodontitis participated in the study . Each patient had 2 buccal mandibular class II furcation defects (first or second molars) were randomizely treated either with : bovine – derived xenograft with Platelet – Rich plasma, or with bovine - derived xenograft alone.
Chronic periodontitis (CP) is an inflammatory disease, characterized by gingivitis, and affecting tooth supporting tissues, forming periodontal pockets with associated attachment loss, alveolar bone resorption. It is common in adults, but can also occur at any age. The rate of disease progression may be influenced by local, systemic conditions, and/or environmental factors that alter the normal host response to bacterial plaque, and affect the susceptibility to disease.It is suggested that periodontitis is partially associated by genetic factors, that many genes are involved in inflammation susceptibility, mainly include the vitamin D receptor (VDR) gene that is implicated in bone metabolism and the host immune response. 80 Syrian subjects were recruited for vitamin D receptor gene polymorphism study, and allocated in two groups: 50 diagnosed with CP and mean age was (64 ± 0.722) years, 30 matched controls. DNA was isolated from peripheral blood cells, and genotyping was performed by polymerase chain reaction (PCR) method and restriction fragment length polymorphism analysis (RFLP) by using FokI enzyme. By using Chi square test, no significant differences were found between the study groups in the frequencies of alleles and genotypes at FokI position of VDR gene, age and sex. These findings suggest that the investigated factors are not associated with periodontal disease in this studied sample of Syrian population.
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